Clinical trials: Hernia Abdominal Wall
Pain, Postoperative, Hernia, Ventral
An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
This is a multicenter, Phase 3, open-label, safety, tolerability, and characterization of pharmacokinetics study of the INL 001 (bupivacaine HCl) implant, at 300 mg, in patients following various soft-tissue surgeries: open…
- Conditions
- Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy
- Trial name
- NCT04785638
- Testing
- INL-001 (bupivacaine hydrochloride) implant
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Innocoll
Hernia, Inguinal
Use of Human Fibrin Glue Versus Staples for Mesh Fixation in Laparoscopic Transabdominal Preperitoneal Hernioplasty
Inguinal hernia repairs belong to the most common surgical procedures worldwide. Increasingly they are performed using endoscopical techniques (laparoscopy).
- Trial name
- TISTA (NCT01641718)
- Testing
- Tissue glue, Staples
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- Sascha Müller
Hernia, Ventral
Transverse Abdominal Plane Anesthesia for Abdominal Wall Reconstruction
The aim of this study is to evaluate the short-term postoperative outcomes in the abdominal wall reconstruction population using an intraoperative local anesthetic infusion.
- Trial name
- NCT02274077
- Testing
- EXPAREL, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chester Mays
Inguinal Hernias
Inguinal Hernia Management: Watchful Waiting vs. Tension-Free Open Repair
Purpose: To determine if observation (watchful waiting is a safe alternative to routine repair of asymptomatic inguinal hernias in adult males.
- Trial name
- NCT01922674
- Testing
- Standard open tension-free inguinal hernia repair with mesh
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Creighton University
Ventral Hernia
The Influence of Closing the Gap on Postoperative Seroma and Recurrences in Laparoscopic Ventral Hernia Repair
A multicenter prospective randomized controlled trial comparing closure versus non-closure of the hernia defect between 2 and 5 cm in width using a tissue separating mesh (Physiomesh™) in laparoscopic ventral hernia repair.
- Trial name
- CLOSURE (NCT01719718)
- Testing
- Closure of hernia defect., No closure of the hernia defect.
- Where
- 6 sites in Belgium
- Volunteers
- 93 people
- Sponsor
- University Hospital, Ghent
Inguinal Hernia
Sutured Versus Cyanoacrylate Glue Mesh Fixation for Inguinal Hernia Repair
Because it avoids direct nerve irritation or entrapment, mesh fixation with tissue adhesive glue seems an optimal option to reduce postoperative pain.
- Trial name
- NCT04203940
- Testing
- Cyanoacryale, Suture
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Delirium in Old Age, Hernia, Inguinal
Effect of Bilateral RSB on Postoperative Delirium in Elderly Patients Undergoing Laparoendoscopic Single-site Surgery
Postoperative delirium is a common complication in clinical surgery. It has been reported that it can increase postoperative morbidity and mortality and lead to decreased functional and cognitive abilities.
- Conditions
- Delirium in Old Age, Hernia, Inguinal, Cholecystolithiasis
- Trial name
- NCT05280860
- Testing
- ultrasound-guided bilateral rectus sheath block
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Affiliated Hospital of Nantong University
Inguinal Hernia, Abdominal Wall Muscles
Transversus Abdominis Plane Block and Inguinal Hernia Repair
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients…
- Conditions
- Inguinal Hernia, Abdominal Wall Muscles, Regional Anesthesia, Postoperative Pain
- Trial name
- NCT02030223
- Testing
- Transversus abdominis plane block
- Where
- Greece
- Volunteers
- 59 people
- Sponsor
- Papacharalampous Panagiota
Hernia, Ventral, Pain Management
Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair
The purpose of this study is to determine whether using a QL block is better than placebo (a look-alike substance that contains no drug) in lowering the amount of opioids you need for pain relief in the first 24 hours and if it…
- Trial name
- VHR (NCT06953635)
- Testing
- Quadratus Lumborum (QL) Block
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Inguinal Hernia, Direct, Child, Only
Analysis of Risk Factors for Children With Heterochronous Indirect Hernia
Laparoscopic contralateral patent processus vaginalis (CPPV) repair in infancy and childhood is still debatable, due to the high CPPV rate but low contralateral metachronous hernia (MCIH) rate.
- Conditions
- Inguinal Hernia, Direct, Child, Only, Laparoscopic Surgery
- Trial name
- NCT05092425
- Testing
- no intervention
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Shanghai Children's Hospital
Inguinal Hernia
M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Inguinal hernia repair is the most common of abdominal surgical procedures and is usually performed laparoscopically. Many factors play a role in the pain that develops after surgery and is generally considered to be visceral…
- Trial name
- NCT05476510
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Hernia, Inguinal
Mesh Fixation and Closure of Peritoneum Following Laparoscopic Hernia Repair Using N-butyl Cyanoacrylate
Fixation of mesh and peritoneal closure during TAPP repair using n-butyl cyanoacrylate.
- Trial name
- NCT02457728
- Testing
- LiquiBandFix8
- Where
- Austria
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna
Ventral and Ventral Insicional Hernia
LVHR Multicenter Study
The study aims to prove differences or equalities in outcome for patients operated with laparoscopic ventral hernia repair with different methods of fixation of mesh and with or without approximation of defect prior to…
- Trial name
- NCT00455299
- Testing
- Laparoscopic ventral hernia repair
- Where
- 2 sites in Norway
- Volunteers
- 156 people
- Sponsor
- Oslo University Hospital
Hernia, Inguinal
Comparative Study of Safety and Efficacy of Heavyweight and Partially Absorbable Mesh in Inguinal Hernia Repair
Proflex® Mesh (partially absorbable mesh, Korea) and Marlex® Mesh (heavyweight mesh) will be used for inguinal hernia repair to compare the safety and efficacy (pain score, quality of life)of two devices at 3 months follow-up.
- Trial name
- NCT01877122
- Testing
- Proflex® Mesh Mesh implantation, Marlex® Mesh Implant
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Ventral Hernia
Conservative Treatment For Ventral Hernia
The aim of this study is to evaluate on which indication patients are offered operative treatment for their ventral hernia, and to investigate the natural course of ventral hernia in the population of patients not offered…
- Trial name
- NCT02263599
- Where
- Denmark
- Volunteers
- 2,089 people
- Sponsor
- Zealand University Hospital
Ventral Hernia
Anovo Surgical System in Ventral Hernia
The study is aimed to clinically assess the AnovoTM Surgical System in ventral hernia procedures. Extensive preclinical testing of the system's integrity and safety has been performed to assure adequate safety for this trial.
- Trial name
- CLEVER (NCT06457971)
- Testing
- Robotic Ventral Hernia Repair
- Where
- 2 sites in Belgium, Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Momentis Surgical
Inguinal Hernia
An Efficiency/Safety Study of Surgical Tissue Glue to Treat Inguinal Hernias
Prospective, multicenter, observational registry to collect data of laparoscopic inguinal hernia repair using surgical tissue glue fixation. The objective is to determine the prevalence of chronic pain at 1 year.
- Trial name
- NCT01669837
- Testing
- Mesh fixation with surgical tissue glue
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- Duomed
Ventral Hernia
The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients
This study evaluates the outcomes of patients who have been treated with Strattice or Gore Bio-A mesh for the repair of complicated abdominal wall hernias.
- Trial name
- NCT01794338
- Testing
- Strattice Arm, Bio-A Arm
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Recurrent Inguinal Hernia
Feasibility of Re-TREPP in Patients With a Recurrent Inguinal Hernia After Previous TREPP Repair
The Trans REctussheath PrePeritoneal (TREPP) mesh repair was introduced in 2006 to decrease the risk of postoperative inguinal pain in hernia surgery.
- Trial name
- re-TREPP (NCT03411226)
- Testing
- re-TREPP
- Volunteers
- 19 people
- Sponsor
- Alexandra Persoon