Clinical trials: Hernia Abdominal Wall
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Transplant;Failure,Kidney, Transplant; Failure, Liver
Abdominal Wall Transplant
The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects.
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Transplant; Failure, Bowel, Abdominal Wall Defect
- Trial name
- NCT03310905
- Testing
- Abdominal Wall Transplant with another solid organ transplant, Abdominal Wall Transplant alone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Recurrent Hernia
Review of Complex Recurrent Hernia Repair
Abdominal wall incisional hernia is a common finding in patients who have undergone previous intra-abdominal surgeries. Common methods of abdominal fascial closure include primary closure, mesh inlay versus onlay, with or without…
- Trial name
- BARS (NCT01644695)
- Testing
- Bony Anchoring Reinforcement System
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Institute For Advanced Reconstruction
Inguinal Hernia
Mastery Learning Inguinal Hernia Repair
Abstract: Minimally invasive techniques are now ubiquitous in the management of surgical disease. Competence in laparoscopy requires specialized training and practice.
- Trial name
- NCT01085500
- Testing
- Mastery Learning TEP Curriculum, Current Practice
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hernia, Umbilical
Intraperitoneal Mesh With 3cm Overlap Versus a Rives-Stoppa Repair With a 6cm Overlap in Hernia Umbilicalis
To study the advantages and disadvantages of a Ventralex prothesis versus Light Weight Vypro II prothesis in patients with a hernia umbilicalis.
- Trial name
- NCT00323141
- Testing
- Ventralex versus Leight Weight Vypro II prothesis
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Inguinal Hernia
Laparoscopic Totally Extraperitoneal Inguinal Hernia Repair With Fibrin Glue Versus Tack Mesh Fixation
The quality of life after hernia surgery like chronic pain and discomfort has frequently been reported with a frequency varying from 0 to 53%. As many as 10% of the patients report increased pain following surgery.
- Trial name
- NCT06679504
- Testing
- Fibrin glue fixation, Tack fixation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Suez Canal University
Inguinal Hernia, Convalescence
Pain and Convalescence After Laparoscopic Groin Hernia Repair
The investigators want to identify limiting factors for short convalescence after laparoscopic groin hernia repair. Before the operation patients are given intensive structured information about one day´s convalescence.
- Trial name
- Lap-Lyske (NCT00962338)
- Testing
- Information
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Zealand University Hospital
Large Midline Ventral Hernia
Anterior Component Separation Versus Posterior Component Separation for Repair of Large Ventral Hernias
This study evaluates effect of anterior component separation and posterior component separation and transversus abdominis muscle release methods for treatment of midline ventral hernias.
- Trial name
- NCT03793738
- Testing
- Anterior component separation, Posterior component separation
- Where
- Georgia
- Volunteers
- 40 people
- Sponsor
- Zaza Demetrashvili
Ventral Hernia
Ventral Mesh Hernioplasty : Laparoscopic Versus Open Sublay
To compare between laparoscopic ventral hernia repair and open sublay technique (recurrence ,operative time ,bleeding ,rate of complication and injury , seroma, post operative pain)
- Trial name
- NCT06149858
- Testing
- hernioplasty
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inguinal Hernia, Inguinal Hernia Repair
TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair
Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic…
- Trial name
- NCT07618884
- Testing
- trans rectus sheath extra-peritoneal procedure (TREPP)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Hernia, Inguinal, Hernia
3D HD Versus 2D HD in Laparoscopic Inguinal Hernia Repair: a Randomized Controlled Trial
The aim of this study is to compare 3D-laparoscopy versus 2D-laparoscopy with the use of HD resolution in inguinal hernia repair in terms of error rating, performance time and subjective assessment.
- Trial name
- NCT02396940
- Testing
- 3D HD laparoscopy, 2D HD laparoscopy
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Inguinal Hernia, Postoperative Pain
Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain
The study carry out is to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy, opiod sparing, adverse effect and clinical value in post-operative pain management.
- Trial name
- NCT01450345
- Testing
- Pregabalin
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- University of Malaya
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Inguinal Hernia,Laparoscopy,Extra-peritoneal
A Comparative Study on Trans-umbilical Single-port Laparoscopic Extra-peritoneal Approach Versus Conventional Repair for Inguinal Hernia in Children
Inguinal hernia is a common disease in children. Treatment of this disease by laparoscopic high ligation of the hernia sac has been accepted by domestic and foreign scholars.
- Trial name
- NCT02960529
- Testing
- extra-peritoneal high ligation of hernia, intraabdominal high ligation of hernia
- Where
- China
- Volunteers
- 300 people
- Sponsor
- zebing Zheng
Ventral Hernia
Surgical Approaches for Medium-to-Large Ventral Hernias: Open, Laparoscopic, and Robotic-Assisted Techniques
The purpose of this project is to investigate whether the use of the new robot-assisted technique in surgery for large and medium-sized ventral midline hernias has brought tangible benefits to patients in terms of Textbook…
- Trial name
- NCT07275346
- Where
- Sweden
- Volunteers
- 750 people
- Sponsor
- Andreas Älgå
Ventral Hernia, Postoperative Pain
Evaluation of Ultrasound-guided Erector Spinae Block for Postoperative Analgesia in Laprascopic Ventral Hernia Repair.
Ventral hernia repair is associated with significant postoperative pain, and regional anesthetic techniques are of potential benefit.
- Conditions
- Ventral Hernia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT04438369
- Testing
- Erector Spinae Plane Block
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold Hospital Trust
Hernia, Inguinal
Impacts of Stoppa and Total Extraperitoneal Inguinal Hernia Repair on the Lower Extremity Muscular Functions
Comparison of physical activity parameters of the lower extremity muscles in patients who received total extraperitoneal repair (TEP) and STOPPA repair.
- Trial name
- NCT02813057
- Testing
- Stoppa inguinal hernia repair, Total extraperitoneal inguinal hernia repair
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Akdeniz University
Unilateral Inguinal Hernia
Evaluation of Mesh Integration and Mesh Contraction After Open Preperitoneal Inguinal Hernia Repair Using a Memory Ring Containing Device
The aim of this study is to evaluate whether preperitoneal mesh placement using a nitinol containing large pore polypropylene mesh (REBOUND HRD™) offers a satisfying patient recovery, quick reconvalescence and adequate tissue…
- Trial name
- REBOUND (NCT01622712)
- Testing
- Rebound HRD Mesh
- Where
- 2 sites in Belgium
- Volunteers
- 235 people
- Sponsor
- University Hospital, Ghent
Inguinal Hernia, Postoperative Pain
Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal hernia repair is one of the most frequently performed operations in young men. Persistent pain after inguinal surgery represents a significant cause of disability, occurring in between 15%-35% of cases.
- Trial name
- NCT00825344
- Testing
- Etanercept, Saline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Incisional Hernia
ACute Treatment of Incisional Ventral Hernia
This observational, retrospective study aims to examine surgical outcomes in non-elective surgery for incisional hernia. The main questions it aims to answer are: 30-day morbidity short- and long-term surgical outcomes Data will…
- Trial name
- ACTIVE (NCT05620121)
- Testing
- Surgery for Incisional hernias
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ospedale San Camillo