Clinical trials: Herniorrhaphy, active
Abdominal Disorder
Evaluation of Laparoscopic Cholecystectomy and Concomitant Paraumbilical Hernia Repair
Umbilical hernia frequently accompanies cholelithiasis. It is possible to repair these hernias after completing cholecystectomy.
- Trial name
- NCT06317779
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Paraesophageal Hernia
Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair
This study will be a prospective observation study of the use of PoRSHA for repair in patients with challenging paraesophageal hernias.
- Trial name
- NCT06551077
- Testing
- POSTERIOR RECTUS SHEATH HIATAL AUGMENTATION (PORSHA)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Chronic Post-surgical Pain
Duloxetine to Prevent Chronic Postsurgical Pain After Inguinal Hernia Repair in Patients at High Risk
The clinical trial will be conducted in 14 Spanish hospitals. It is estimated, based on our previous studies, that 2855 patients scheduled for elective inguinal hernia surgery will have to be assessed to detect patients with ≥…
- Trial name
- GENDOLCAT3 (NCT06606067)
- Testing
- Duloxetine
- Where
- Spain
- Volunteers
- 294 people
- Sponsor
- Parc de Salut Mar
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Hernia Incisional Ventral
LIQUIBAND FIX8® for Ventral Incisional Hernia
This study is designed to evaluate the safety and performance of device LiquiBand FIX8 Open hernia mesh fixation device. The use of this device is not experimental, as it is already approved for use in the EU (CE-marked).
- Trial name
- LBF8-03 (NCT07295379)
- Testing
- LIQUIBAND FIX8
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Advanced Medical Solutions Ltd.
Patients Undergoing Laparoscopic Inguinal Hernia Repair
The Effect of Cold Vapor on Dyspnea, Thirst, Nausea, and Physiological Parameters in the PACU After Laparoscopic Inguinal Hernia Surgery
Cold vapor application is considered a promising intervention with the potential to alleviate side effects associated with anesthesia and surgery in the postoperative period.
- Trial name
- NCT07273162
- Testing
- Cold Vapor
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- TC Erciyes University
Hernia, Ventral, Hernia, Inguinal
Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh
This study is designed to evaluate the post-operative complications and hernia recurrence following the use of OviTex in subjects with ventral or inguinal hernias.
- Trial name
- BRAVOII (NCT04779918)
- Testing
- OviTex Reinforced Tissue Matrix
- Where
- 10 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tela Bio Inc
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Emergence Delirium, Anesthesia
Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children
This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will…
- Trial name
- NCT07799311
- Testing
- propofol 1mg/kg, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Ventral Hernia Repair
Cost-Effectiveness of Retromuscular Hernia Repair
This prospective observational study aims to evaluate the clinical outcomes and cost-effectiveness of retromuscular midline ventral hernia repair using open, laparoscopic and robotic approaches.
- Trial name
- ECOHERNIA-3 (NCT07530159)
- Testing
- Retromuscular ventral hernia repair, Polypropylene mesh, Standard perioperative care
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fátima Hinojosa Ramírez
Lumbar Hernia
On-lay Versus Pre-peritoneal Hernioplasty in Incisional Lumbar Hernia
To compare between the outcome of on-lay and pre-peritoneal techniques of hernioplasty in incisional lumbar hernia repair.
- Trial name
- NCT06757998
- Testing
- Mesh
- Volunteers
- 30 people
- Sponsor
- Assiut University
Abdominal Wall Hernia
Hernia Repair Using Rectus Fascia Allograft
Abdominal wall closure in highly complex patients is one of the most difficult tasks in abdominal surgery. Repeated laparotomies, enterocutaneous fistulas, loss of the fascial layer and contaminated operative fields may prevent…
- Trial name
- NCT07326826
- Testing
- Allogeneic non-vascularized rectus abdominis fascial graft (NVRF)
- Volunteers
- 20 people
- Sponsor
- Institute for Clinical and Experimental Medicine
We Are Studying the Effects of Caudal Dexamethasone in Neonates Undergoing Inguinal Hernia Repair
Caudal Dexamethasone - Bupivacaine in Neonates
Randomied controlled study Evaluate the effects of caudal Dexamethasone in neonates
- Trial name
- NCT07609836
- Testing
- We add Dexamethasone to Bupivacaine as adjuvant to Bupivacaine in neonsates undergoing inguinal hernia repair in Dexamethasone - Bupivacaine group
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Ventral Hernia Midline, Hernia Lumbar
Prospective Study of Minimally Invasive (Laparoscopic and Robotic) Hernia Repair (Incisional and Primary, Midline and Lateral, Not Inguinal)
The participating researchers register all adult patients (who have given informed written consent) scheduled for elective repair of an abdominal wall hernia (NOT inguinal hernias) via minimally invasive operation technique…
- Conditions
- Ventral Hernia Midline, Hernia Lumbar, Incisional Hernia Repair
- Trial name
- PROMISER (NCT07544238)
- Testing
- Minimally invasive hernioplastia
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Hernia, Ventral, Hernia Incisional
Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application
The SYN 20-01 Study is a non-interventional, prospective, multicenter, multicohort, international, post-market clinical investigation looking into the assessment of GORE® SYNECOR Biomaterial in focused patient populations and in…
- Conditions
- Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
- Trial name
- SYN 20-01 (NCT05094089)
- Testing
- Hernia repair with mesh
- Where
- 15 sites in United States, Italy and 2 more
- Volunteers
- 320 people
- Sponsor
- W.L.Gore & Associates
Inguinal Hernia, Ventral Hernia
Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs
While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is…
- Trial name
- NCT05177991
- Testing
- Liposomal Bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Leslie Son
Hernia, Inguinal, Robotic Surgical Procedures
Robotic vs. Conventional Minimal-invasive Inguinal Hernia Repair
Minimal invasive techniques have become a well established approach for inguinal hernia repair over the last decade in developed countries.
- Trial name
- ROGER-RCT (NCT05216276)
- Testing
- TEP, rTAPP
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Basel, Switzerland
Inguinal Hernia, Femoral Hernia
Laparoscopic Inguinal and Femoral heRniA rePaIr Using Pre-shapeD 4DMESH® (4DLap)
The purpose of this study is to evaluate the safety and performance of the 4DMESH® used in (robot-assisted) laparoscopic inguinal and femoral hernia repair.
- Trial name
- NCT05306496
- Testing
- Pre-shaped 4DMESH®
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 196 people
- Sponsor
- Cousin Biotech
Laparoscopic Surgery, Laparoscopic Appendectomy
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Laparoscopic Surgery
Incisional infiltration is the simplest, safest, and most effective anesthesia method for preventing incision pain after laparoscopic surgery, but even using long-acting local anesthetics, the effectiveness of postoperative…
- Conditions
- Laparoscopic Surgery, Laparoscopic Appendectomy, Laparoscopic Cholecystectomy, Laparoscopic Hernia Repair Surgery
- Trial name
- NCT07626463
- Testing
- Pre-incisional infiltration with ropivacaine and diprospan, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Inguinal Hernias
Urinary Catheterization Versus No Catheterization in Laparoscopic Total Extraperitoneal Inguinal Hernia Repair
The goal of this randomized controlled clinical trial is to determine whether avoiding routine urinary catheterization reduces postoperative urinary symptoms in patients undergoing laparoscopic totally extraperitoneal (TEP)…
- Trial name
- TEP-CAT (NCT07886814)
- Testing
- Routine Urinary Catheterization, No Routine Urinary Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ugur Duman