Clinical trials: Herpes Labialis
Cold Sores
Post-marketing Study for the Evaluation of Profilm Cold Sores
Experimental clinical study with a post-marketing, prospective, intra-subject controlled design to evaluate the efficacy and safety of the use of a medical device for the treatment of cold sores, over a maximum period of two…
- Trial name
- NCT06734728
- Testing
- Profilm Cold Sores
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- i+Med S.Coop.
Herpes Labialis
Study of a Cold Sore Patch for the Treatment of Herpes Labialis
If a person qualifies to participate in this study, they will have an equal chance of being assigned to either of two groups. One group will receive a patch that they will need to carry with them, because as soon as a cold sore…
- Trial name
- NCT01484067
- Testing
- Patch ( Compeed© Total CareTM Cold Sore Patch)
- Where
- United Kingdom
- Volunteers
- 472 people
- Sponsor
- Johnson & Johnson Consumer Products Company Division of Johnson & Johnson Consumer Companies, Inc.
Herpes Labialis
Bioequivalence Study of Aciclovir 5% Cream in Japanese Healthy Volunteers
This study is designed to show bioequivalence between Current and New formulation of Aciclovir cream 5% in keratin layer of the epidermis in Japanese Subjects
- Trial name
- NCT00711776
- Testing
- New formulation, Current formulation
- Where
- Japan
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Herpes Labialis
Comparative Safety and Efficacy of Two Antiviral Treatments in the Treatment of Recurrent Herpes Simplex Labialis
To compare safety and efficacy of Perrigo's antiviral drug product compared to an FDA approved antiviral drug product in the treatment of cold sores.
- Trial name
- NCT02265913
- Testing
- Acyclovir 5 percent (Perrigo), Acyclovir 5 percent (Reference)
- Where
- United States
- Volunteers
- 4,076 people
- Sponsor
- Padagis LLC
Recurrent Herpes Labialis
A Study to Evaluate the Safety and Efficacy of Single Day or Single Dose Famciclovir for the Treatment of Recurrent Herpes Labialis
The study is designed to assess the efficacy and safety of patient-initiated therapy with famciclovir 1500 mg o.d. or 750 mg b.i.d. for one day treatment in adult men and women with recurrent herpes labialis
- Trial name
- NCT00248144
- Testing
- Famciclovir
- Sponsor
- Novartis
HSV, Herpes Labialis
Immune Response and General Immune Health in Subjects Infected With Herpes Simplex Virus Type 1 (HSV-1)
Subjects were recruited who were positive for antibody against herpes simplex virus type 1 (HSV-1) and self-reported having in the previous 12 months 6 or more herpes labialis outbreaks (group A), 1 or 2 outbreaks (group B), or…
- Trial name
- NCT03661541
- Testing
- Squaric Acid Dibutyl Ester
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Squarex, LLC
Cold Sores
An Investigation Into the Efficacy of Herpecin L at Reducing the Frequency and Severity of Cold Sores
Focus Consumer Healthcare has developed Herpecin L. Herpecin L combines many different ingredients hypothesized to promote quick healing and symptom reduction from cold sores.
- Trial name
- NCT05796635
- Testing
- Herpecin L
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Focus Consumer Healthcare
Herpes Labialis
NB-001 Treatment of Recurrent Herpes Labialis
This is a study to test the hypothesis that time to healing of a cold sore will be lower in the active treatment arm of the study when compared to the vehicle (placebo).
- Trial name
- NCT01695187
- Testing
- NB-001 (0.3%)
- Where
- 12 sites in United States
- Volunteers
- 362 people
- Sponsor
- NanoBio Corporation
Recurrent Herpes Labialis
A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis (SHaRCS)
The purpose of this study is to demonstrate the safety and efficacy of NB-001 in subjects with recurrent herpes labialis (RHL).
- Trial name
- SHaRCS (NCT01324466)
- Testing
- NB-001, Vehicle
- Where
- 35 sites in United States
- Volunteers
- 847 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
Oral Herpes Simplex
Evaluation of Cold Sore Treatments on Ultra Violet (UV) Induced Cold Sores
The purpose of this study is to determine if a new drug treatment is effective to block the development of a cold sore lesion following Ultra Violet (UV) exposure.
- Trial name
- NCT01902303
- Testing
- BTL-TML-HSV
- Where
- 3 sites in United States
- Volunteers
- 303 people
- Sponsor
- Beech Tree Labs, Inc.
Herpes Labialis
Efficacy of Acyclovir in Combination With a Glucocorticosteroid on UV-Induced Herpes Labialis
The primary objective was to compare the efficacy of ME-609 cream vs placebo cream on the time to healing (loss of hard crust) of delayed classical herpes labialis (HSV) lesions experimentally induced after ultra violet radiation…
- Trial name
- NCT00736437
- Testing
- ME-609, Vehicle
- Volunteers
- 417 people
- Sponsor
- Medivir
Herpes Labialis
Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial Herpes
Randomized, double-blind, multi-center, three arm parallel group, comparative trial to assess pritelivir ointment safety and efficacy, ie, proportion of subjects with non-ulcerative lesions, in adult subjects with recurrent…
- Trial name
- LipP1 (NCT02871492)
- Testing
- Pritelivir 5% w/w ointment, Zovirax® cream
- Where
- 10 sites in United States
- Volunteers
- 362 people
- Sponsor
- AiCuris Anti-infective Cures AG
Herpes Labialis
Safety, Pharmacokinetics, and Efficacy Study of NB-001 to Treat Recurrent Herpes Labialis
Purpose of this study is to determine the safety and efficacy of topical applications of NB-001 as compared to placebo for the treatment of recurrent herpes labialis.
- Trial name
- NCT00453401
- Testing
- NB-001
- Where
- 28 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
Herpes Labialis
Study to Evaluate Using a Cold Sore Patch to Treat Herpes Labialis
The primary objective of this study was to evaluate the safety and performance of a cold sore patch for the treatment of herpes labialis.
- Trial name
- NCT01208298
- Testing
- Cold Sore Patch
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Herpes Simplex
Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex Infection
This study will evaluate the safety and blood levels of a new pediatric formulation of Famvir in children 1-12 years of age. In Part A, patients will receive a single dose of famciclovir (12.5 mg/kg) to assess pharmacokinetics…
- Trial name
- NCT00098059
- Testing
- Famciclovir
- Where
- 13 sites in United States, Panama
- Volunteers
- 74 people
- Sponsor
- Novartis Pharmaceuticals
Recurrent Herpes Labialis
An Open Label Study to Evaluate the Safety and Efficacy of BOR15001L7 for the Treatment of Cold Sores in Patients With Recurrent Herpes Labialis
BOR15001L7 is a natural product. The primary objective of this study is to demonstrate its non-inferiority to docosanol 10% based on the healing time of cold sores in patients with recurrent herpes labialis.
- Trial name
- NCT03977792
- Testing
- BOR15001L7, Docosanol Cream 10%
- Volunteers
- 164 people
- Sponsor
- Laboratoire Boreaderme Inc.
Herpes Labialis
A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex Labialis
Recurrent herpes labialis are usually a minor malady of limited duration, although they are often painful and are uniformly discomforting for patients.
- Trial name
- NCT02207881
- Testing
- VDO gel
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Herpes Labialis
Study of a New Topical Natural Health Product for the Treatment of Herpes Labialis
The aim of this study is to determine the safety and efficacy of a topical natural health product in comparison to placebo for the treatment of herpes labialis.
- Trial name
- NCT02582086
- Testing
- BOR15001L7
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laboratoire Boreaderme Inc.
Herpes Labialis
Iontophoretic Application of Acyclovir Gel to Treat Cold Sores
Currently approved drugs for the treatment of herpes labialis (cold sores) exhibit low levels of efficacy due to the limited ability of the drugs to penetrate the skin to the sites where the herpes virus is replicating.
- Trial name
- NCT00469300
- Testing
- Iontophoretic delivery of acyclovir
- Where
- 13 sites in United States
- Volunteers
- 810 people
- Sponsor
- Transport Pharmaceuticals
Herpes Labialis
VALTREX(Valacyclovir) Once Daily for Viral Shedding In Subjects Newly Diagnosed With HSV-2
Eligible subjects will be randomized to receive VALTREX 1g or placebo once daily for 60 days in a two-way crossover study with a washout period of 7 days in between.
- Trial name
- NCT00306293
- Testing
- valacyclovir
- Where
- 18 sites in United States
- Volunteers
- 70 people
- Sponsor
- GlaxoSmithKline