Clinical trials: Hiatal Hernia
Hiatal Hernia
Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair
The aim of this study is to find out if using a certain kind of mesh can reduce the chances of hiatal hernias coming back after anti-reflux surgery.
- Trial name
- NCT06444347
- Testing
- Biosynthetic Mesh, Hiatal Hernia Repair
- Where
- 6 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Gastroesophageal Reflux
Antireflux Efficacy of Hiatal Hernia Repairs in Sleeve Gastrectomy Patients
Gastroesophageal reflux (GR) occurrence or persistence following a sleeve gastrectomy (SG) can be correlated to several factors but it is clear that one of the key factors is a persistent hiatal hernia or laxity of the esophageal…
- Trial name
- NCT04433507
- Testing
- Sleeve gastrectomy, Hiatal Hernia repair
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Paraesophageal Hernia
Effect of Hernia Sac Excision on Crural Tension in Paraesophageal Hernia Repair
Paraesophageal hernia can cause significant clinical symptoms, including reflux, chest pain, nausea, regurgitation, and even life threatening conditions such as bowel obstruction, and gastric volvulus.
- Trial name
- NCT07197619
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Corewell Health West
Paraesophageal Hernia
Short Esophagus in Type II-IV Hiatus Hernia
Background: The existence, diagnosis and treatment of short esophagus is one of the controversies of the past which has recently re-emerged.
- Trial name
- SEHH (NCT01587859)
- Testing
- laparoscopic surgery
- Where
- 2 sites in Italy
- Volunteers
- 34 people
- Sponsor
- University of Bologna
Paraesophageal Hernia, Hiatal Hernia
Sutures Versus Polyglactin Mesh in Hiatal Hernia Repair
Paraesophageal hernia causes pain, heartburn, regurgitation, anemia and in extreme, life-threatening strangulation. For symptomatic patients, laparoscopic surgery is offered which includes hiatal defect closure and antireflux…
- Conditions
- Paraesophageal Hernia, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Recurrence
- Trial name
- NCT05201508
- Testing
- Polyglactin mesh, Sutures only
- Where
- Finland
- Volunteers
- 110 people
- Sponsor
- Oulu University Hospital
Laparoscopic Toupet Fundoplication, Radiological Negative
Laparoscopic Toupet's Fundoplication: Is it Proper Solution of Radiological Negative, Endoscopically Positive Hiatal Hernia Patients
This study aims to assess the feasibility and effectiveness of laparoscopic toupet fundoplication (LTF) for treating gastroesophageal reflux disease (GERD) symptoms and disease-specific Quality of Life (QoL).
- Conditions
- Laparoscopic Toupet Fundoplication, Radiological Negative, Endoscope, Hiatal Hernia
- Trial name
- NCT06884800
- Testing
- Laparoscopic toupet fundoplication
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Gastroesophageal Reflux Disease, Hiatal Hernia
Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)
The study objective is to evaluate the relative merits, safety and effectiveness of transoral incisionless fundoplication (TIF) in proton pump inhibitor (PPI) dependent GERD patients compared with sham procedure.
- Trial name
- NCT01110811
- Testing
- Transoral Incisionless Fundoplication (TIF)
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 60 people
- Sponsor
- EndoGastric Solutions
Predictive Validity of VLaHHS
Development and Validation of Virtual Laparoscopic Hiatal Hernia Simulator
Part 3 Phase III of this protocol is the interventional portion and is the reason why only this Part is registered and reported within this record.
- Trial name
- (VLaHHS) (NCT06974383)
- Testing
- Training with Virtual Laparoscopic Hiatal Hernia Simulator (VLaHHS)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Body Weight, Post-Op Complication
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)
This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score).
- Conditions
- Body Weight, Post-Op Complication, Anastomosis, Leaking, Hiatal Hernia
- Trial name
- NCT05710913
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
Hiatal Hernia
A Prospective Randomised Multi - Center Trial on the Repair of Large Hiatal Hernias: Absorbable Mesh vs. Pledgeted Sutures vs. Sutures Only
A prospective randomised multi - center trial on the repair of large hiatal hernias with sutures versus pledgeted sutures versus absorbable mesh The primary objective of the present trial is to compare the hiatal hernia…
- Trial name
- NCT04591860
- Testing
- Laparoscopic or robot-assisted hiatal closure (sutures only vs. absorbable mesh vs. pledgeted sutures) and fundoplication according to Toupet
- Volunteers
- 165 people
- Sponsor
- Paracelsus Medical University
Hernia, Hiatal, Pneumoperitoneum
Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair
The goal of this clinical trial is to evaluate the incidence and severity of post-operative shoulder pain following elective robot-assisted hiatal hernia repair in hopes of reducing pain and associated costs as well as clinic and…
- Conditions
- Hernia, Hiatal, Pneumoperitoneum, Postoperative Pain, Shoulder Pain
- Trial name
- NCT06737068
- Testing
- Low pressure pneumoperitoneum (8-10mmHg) with AirSeal device, Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Riverside University Health System Medical Center
Hiatus Hernia
Prevalence of Hiatus Hernia in Gastro-Esophageal Reflux Disease Patients Underwent Upper Endoscopy
To study the prevalence of hiatus hernia in GERD patients underwent upper endoscopy To study the effect of hiatus hernia on the severity of GERD symptoms.
- Trial name
- NCT06155851
- Testing
- Upper Endoscopy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Hiatus Hernia
Hiatus Hernia in Old
hiatus hernia in frail patient is common and requires suregry
- Trial name
- NCT06935617
- Testing
- nissein
- Volunteers
- 266 people
- Sponsor
- Zagazig University
Hiatal Hernia Large, Reflux, Gastroesophageal
Platelet Rich Plasma in Hiatal Hernia Repair
Rationale: Gastroesophageal reflux disease (GERD) is a common disease caused by a dysfunctional lower esophageal sphincter and an abnormal esophageal hiatus or hiatal hernia.
- Trial name
- PPR-HHR (NCT05023174)
- Testing
- Hiatal Hernia Repair with Platelet Rich Plasma, Hiatal Hernia Repair without Platelet Rich Plasma
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Southern California
Hiatal Hernia
Usage of Biological Patch Versus Plastic in the Laparoscopic Repair of Hiatal Hernias
The purpose of this study is to observe the effective and safety in the laparoscopic repair of hiatal hernia using biological patch versus plastic.
- Trial name
- NCT02328248
- Testing
- Biological patch
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastroesophageal Reflux
Manual Therapy and Gastroesophageal Reflux Disease in Patients With Hiatal Hernia
Introduction: Gastroesophageal reflux disease (GERD) is highly prevalent in our society. The association between GERD and hiatal hernia has been shown to be etiologically critical in the onset or worsening of these patients'…
- Trial name
- NCT05283447
- Testing
- Osteopathic Medicine, Control
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Escoles Universitaries Gimbernat
Hernia, Hiatal, GERD (Gastroesophageal Reflux Disease)
TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD), characterized by pathological reflux of gastric contents, affects 10%-20% of the global population with Western predominance and escalating incidence over recent decades.
- Trial name
- NCT07252115
- Testing
- Laparoscopic total left-sided surgical approach, Laparoscopic traditional bilateral approach
- Where
- 2 sites in China
- Volunteers
- 143 people
- Sponsor
- Beijing Friendship Hospital
Achalasia, Paraesophageal Hernia
Minimally Invasive Surgery of the Gastro-esophageal Junction
This study will assess short and long term outcomes of individuals undergoing minimally invasive surgery of the gastro-esophageal junction (MISGEJ).
- Conditions
- Achalasia, Paraesophageal Hernia, GERD, Epiphrenic Diverticula
- Trial name
- MISGEJ (NCT01799967)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Hiatal Hernia Large
Recurrence Rate After Laparoscopic Repair of Large Hiatal Hernia
Patients who underwent laparoscopic repair of large hiatal hernias and anterior fundoplication with mesh are examined for their recurrence rate one year after surgery.
- Trial name
- NCT03025932
- Testing
- repair of giant hiatal hernia with mesh and anterior fundoplication
- Volunteers
- 200 people
- Sponsor
- Prof Urs Zingg
Hiatal Hernia, GERD
Laparoscopic Total Left-sided Surgical Approach Versus Traditional Bilateral Surgical Approach for Hiatal Hernia
Background: In China, guidelines for the treatment of hiatal hernia (HH) are lacking. Furthermore, efficacy and safety assessments of surgical approaches for HH and for the protection of the vagus nerve and organ function are…
- Trial name
- NCT06828627
- Testing
- TLSA, TBSA
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Beijing Friendship Hospital