Clinical trials: Hiatus Hernia
Gastroesophageal Reflux Disease, Hiatal Hernia
Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)
Laparoscopic Nissen Fundoplication has established itself as the procedure of choice in the surgical management of the majority of patients suffering from gastroesophageal reflux disease (GERD).
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Barrett's Esophagus, Esophagitis
- Trial name
- NCT00872755
- Testing
- Nissen, Gastropexy
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- G. Hatzikosta General Hospital
Hernia, Hiatal
Laparoscopic Repair of Giant Hiatal Hernias With Nitinol-framed Lightweight Polytetrafluoroethylene Mesh
This study is prospective randomized trial enrolling at least 50 participants which compares efficacy and safety of two alternative methods of laparoscopic hiatal repair for giant (i.e.
- Trial name
- GIANT (NCT01780285)
- Testing
- Nitinol-framed lightweight PTFE mesh for hiatal repair, Partially absorbable lightweight mesh for hiatal repair
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Odessa National Medical University
Esophagogastric Junction Distensibility, Hiatal Hernia
Esophagogastric Junction Distensibility During Hiatal Hernia Repair
The investigators aim to ascertain the effects of hiatal hernia repair and fundoplication on the distensibility of the esophagogastric junction (EGJ) as measured by FLIP topography/impedance planimetry.
- Trial name
- NCT04450628
- Testing
- EndoFLIP
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Gastroesophageal Reflux Disease, Hiatal Hernia
Registry of Outcomes From AntiReflux Surgery
Prospective registry comparing outcomes after laparoscopic treatment of gastroesophageal reflux disease and hiatal hernia.
- Trial name
- ROARS (NCT02923362)
- Testing
- Laparoscopic Fundoplication, LINX Antireflux
- Where
- 19 sites in United States
- Volunteers
- 1,941 people
- Sponsor
- The Heartburn Foundation
Predictive Validity of VLaHHS
Development and Validation of Virtual Laparoscopic Hiatal Hernia Simulator
Part 3 Phase III of this protocol is the interventional portion and is the reason why only this Part is registered and reported within this record.
- Trial name
- (VLaHHS) (NCT06974383)
- Testing
- Training with Virtual Laparoscopic Hiatal Hernia Simulator (VLaHHS)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hiatal Hernia, Paraesophageal, Hiatal Hernia Large
Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia.
This randomized controlled trial compares laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in patients undergoing surgical treatment for hiatal hernia associated with gastroesophageal reflux disease.
- Conditions
- Hiatal Hernia, Paraesophageal, Hiatal Hernia Large, Hiatal Hernia With Gastroesophageal Reflux Disease
- Trial name
- NCT07718828
- Testing
- Laparoscopic Nissen Fundoplication, Laparoscopic Toupet Fundoplication
- Where
- Bulgaria
- Volunteers
- 200 people
- Sponsor
- Sofia Med Hospital
Hiatal Hernia, GERD
Laparoscopic Total Left-sided Surgical Approach Versus Traditional Bilateral Surgical Approach for Hiatal Hernia
Background: In China, guidelines for the treatment of hiatal hernia (HH) are lacking. Furthermore, efficacy and safety assessments of surgical approaches for HH and for the protection of the vagus nerve and organ function are…
- Trial name
- NCT06828627
- Testing
- TLSA, TBSA
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Beijing Friendship Hospital
Oesphageal Cancer, Para-conduit Hernia
The PHARO Trial: The Incidence of Para-conduit Hernia With Closure of Hiatus Versus the Standard Approach in Robotic Oesophagectomy - A Randomised Controlled Pilot Trial
Para-conduit hernia is a recognised complication following minimally invasive and robotic oesophagectomy. It may present as an incidental radiological finding or as a symptomatic hernia requiring urgent surgical intervention.
- Trial name
- PHARO (NCT07426835)
- Testing
- Standard Hiatal Management, Hiatal Closure With Omentopexy and Left Crus Fixation
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Royal College of Surgeons, Ireland
Paraesophageal Hernia, Large Hiatal Hernia
Ovitex in Paraesophageal and Large Hiatal Hernia Repair
The purpose of the study is to evaluate the success of hiatal hernia repairs in patients with large (>5cm) or paraesophageal hernias when Ovitex LPR mesh used during the repair.
- Trial name
- OviPHeR (NCT06193551)
- Testing
- Ovitex LPR
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Foregut Research Foundation
Hiatal Hernia Large, Gastro Esophageal Reflux
LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm
The cohort registry is both retrospective and prospective, multicenter surveillance of subjects who underwent a prior hiatal hernia repair and Magnetic Sphincter Augmentation or fundoplication construction more than 2 years prior…
- Conditions
- Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal
- Trial name
- NCT04695171
- Testing
- LINX Reflux Management System, Fundoplication
- Where
- 6 sites in United States
- Volunteers
- 336 people
- Sponsor
- Foregut Research Foundation
Hernia, Hiatal, GERD (Gastroesophageal Reflux Disease)
TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD), characterized by pathological reflux of gastric contents, affects 10%-20% of the global population with Western predominance and escalating incidence over recent decades.
- Trial name
- NCT07252115
- Testing
- Laparoscopic total left-sided surgical approach, Laparoscopic traditional bilateral approach
- Where
- 2 sites in China
- Volunteers
- 143 people
- Sponsor
- Beijing Friendship Hospital
Shoulder Pain, Hiatal Hernia
Pain Relief After Hiatal Hernia Repair Surgery
Referred shoulder pain (pain felt when the problem is actually in a different location) is very common after laparoscopic (small, narrow cut) hernia surgery.
- Trial name
- NCT04936711
- Testing
- Resteck Shiatsu Neck and Back Massager, Marcaine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Norton Thoracic Institute
GERD, Hiatal Hernia
Can EndoFLIP Improve Quality of Life Before and After Fundoplication?
Patients with reflux disease (heart burn), or a hiatal hernia, who do not get better with medication, may have surgery to help with their symptoms. Unfortunately, there is no agreed upon way to perform the surgery.
- Trial name
- NCT06159972
- Testing
- EndoFLIP
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Dr. Wiley Chung
Hernia, Hiatal, Pneumoperitoneum
Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair
The goal of this clinical trial is to evaluate the incidence and severity of post-operative shoulder pain following elective robot-assisted hiatal hernia repair in hopes of reducing pain and associated costs as well as clinic and…
- Conditions
- Hernia, Hiatal, Pneumoperitoneum, Postoperative Pain, Shoulder Pain
- Trial name
- NCT06737068
- Testing
- Low pressure pneumoperitoneum (8-10mmHg) with AirSeal device, Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Riverside University Health System Medical Center
Hiatal Hernia, Paraesophageal Hernia
Nissen Versus Dor Hiatal Hernia Repair
Hiatal hernia can present with a wide range of symptoms. An usual surgical repair technique usually includes Nissen fundoplication, while other procedures are less frequently employed.
- Conditions
- Hiatal Hernia, Paraesophageal Hernia, Recurrence
- Trial name
- NiDor (NCT06725433)
- Testing
- Nissen fundoplication, Dor fundoplication
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- Kuopio University Hospital
Morbid Obesity, Hiatal Hernia
Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients
Background: Obesity and hiatal hernia are both risk factors of gastroesophageal reflux disease (GERD), and the incidence of hiatal hernia is much higher in morbidly obese patients.
- Conditions
- Morbid Obesity, Hiatal Hernia, Gastroesophageal Reflux Disease, Sleeve Gastrectomy
- Trial name
- NCT03776669
- Testing
- Laparoscopic sleeve gastrectomy + Hiatal hernia repair, Laparoscopic sleeve gastrectomy alone
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Hiatal Hernia, Gastroesophageal Reflux Disease
Approach to Hiatal Hernia Repair Based on Collagen Study
Groups of patients who underwent laparoscopic repair of large hiatal hernias by primary posterior crural repair and crural repair with ProGrip™ mesh techniques were examined for recurrence rate of hiatal hernias, quality of life…
- Trial name
- NCT04152798
- Testing
- Laparoscopic hiatal hernia repair with ProGrip™ mesh, Laparoscopic primary posterior crural repair
- Volunteers
- 140 people
- Sponsor
- Grubnik Volodymyr