Clinical trials: High Blood Pressure
Hypertension
A Comparative Study Between Amlodipine 10mg And 5mg With Hypertension For Whom 5mg Is Insufficient
The changes in the trough systolic blood pressure from the baseline were assessed after 8 weeks of double-blind treatment with amlodipine 10 mg or amlodipine 5 mg
- Trial name
- NCT00415623
- Testing
- Amlodipine
- Where
- 14 sites in Japan
- Volunteers
- 305 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypertension, Insulin Resistance
Treatment of Insulin Resistance in Hypertensive, Obese Adolescents
In this study, we propose using telmisartan, an angiotensin II receptor antagonist with PPAR-gamma modulating activity, for a 12-week period to decrease blood pressure and insulin levels in obese, hypertensive children.
- Conditions
- Hypertension, Insulin Resistance, Dyslipidemia
- Trial name
- NCT00185705
- Testing
- Telmisartan
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
High Blood Pressure
COMPLIANCE An Observational Study of Treatment Compliance and Quality of Life in Patients on Antihypertensive Medication
The aim of this multi-centre survey is to assess treatment adherence and quality of life in a Jordanian and Lebanese population newly diagnosed with hypertension or with uncontrolled essential hypertension being on…
- Trial name
- NCT01274494
- Volunteers
- 1,501 people
- Sponsor
- AstraZeneca
Pulmonary Hypertension
Persistent Pulmonary Hypertension After Percutaneous Mitral Commissurotomy
To identify clinical, echocardiographic, and hemodynamic parameters which can predict persistent PH after PMC, and also to determine the impact of persistent PH on the clinical outcomes.
- Trial name
- NCT04083729
- Testing
- Percutaneous Mitral Commissurotomy
- Volunteers
- 62 people
- Sponsor
- Assiut University
Hypertension
Pharmacists Intervention to Improve Hypertension Management in Primary Care
Arterial hypertension is the single largest contributor to mortality world-wide, and only 30-50% of diagnosed and treated patients achieve their blood pressure goal.
- Trial name
- APOTHECARE (NCT03274531)
- Testing
- Referral of hypertensive patients to the attending physician
- Where
- 54 sites in Austria
- Volunteers
- 497 people
- Sponsor
- Wilhelminenspital Vienna
Improving Blood Pressure Control
Taxi METERS: Measuring Effectiveness of Technology, Education, Referrals and Support
In our past work it was found that many drivers had high blood pressure, and lifestyles that led to being overweight and not having cancer screenings performed.
- Trial name
- NCT02701829
- Testing
- CONTROL- Usual & Customary Health Fair Follow-up, Health Fair + TECH [Text Messaging + Home Blood Pressure Monitoring], Heal th Fair + TECH [Text Messaging + Home Blood Pressure Monitoring] + Social Network Support (SNS)
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hypertension, Diabetes Mellitus
Diabetes Risk Evaluation and Microalbuminuria in Saskatchewan First Nations Peoples
This randomized controlled trial was designed to assess whether a community-based treatment strategy implemented by home care nurses would be effective in controlling hypertension in First Nations people with existing…
- Trial name
- DREAM3 (NCT00741702)
- Testing
- Nurse administered treatment algorithm
- Volunteers
- 95 people
- Sponsor
- Sunnybrook Health Sciences Centre
Blood Pressure
Magnesium Supplementation and Blood Pressure Reduction
This double-blind, placebo-controlled randomized clinical trial will test whether a magnesium glycinate supplement (480 mg/day) taken for 12 weeks lowers blood pressure.
- Trial name
- NCT03688503
- Testing
- magnesium glycinate supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pulmonary Hypertension
A Dose Response Study of UT-15C SR in Patients With Exercise-Induced Pulmonary Hypertension
This is a prospective, randomized, parallel group study to assess the hemodynamic effect of three different dose regimens of a sustained release (SR) tablet of UT-15C in patients with exercise-induced pulmonary hypertension (PH)…
- Trial name
- NCT01104870
- Testing
- UT-15C
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- United Therapeutics
Essential Hypertension
Effects of Remote Ischemic Conditioning on Blood Pressure in Older Patients With Hypertension
The purpose of this study is to learn about effects of remote ischemic conditioning on blood pressure in older patients with essential hypertension.
- Trial name
- NCT05845905
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Yi Yang
Glaucoma
Greek Physicians Perceptions Regarding Generics Prescribing in Glaucoma
This attempts to investigate the perceptions of Greek Ophthalmologists regarding generics prescription in glaucoma by means of a structured questionnaire.
- Trial name
- NCT01855802
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Democritus University of Thrace
Pulmonary Arterial Hypertension
A Study of Sotatercept in Japanese Pulmonary Arterial Hypertension (PAH) Participants (MK-7962-020)
This local Phase 3 study is planned to confirm the efficacy and safety in Japanese PAH participants. The primary population of this study is Japanese PAH participants with World Health Organization Functional Class (WHO FC) II or…
- Trial name
- NCT05818137
- Testing
- Sotatercept
- Where
- 17 sites in Japan
- Volunteers
- 46 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension
Mobilizing Community Hypertension Access Pilot
The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted…
- Trial name
- NCT07547345
- Testing
- Community-Based Multidisciplinary Hypertension Management Program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Arterial Hypertension
The Role of Genetic Factors in the Development of Arterial Hypertension in the Kazakh Population
This is a GWAS study that aims to identify possible candidate genes associate to arterial hypertension by exploring single nucleotide polymorphism (SNP) in a group of arterial hypertension, in the Kazakh population.
- Trial name
- NCT05088486
- Testing
- DNA analysis
- Where
- Kazakhstan
- Volunteers
- 1,200 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Heart Failure, Pulmonary Hypertension
Sildenafil in US Heart Failure Patients (SilHF-US)
This protocol describes a 2-arm randomized controlled pilot study assessing the tolerance, safety and efficacy of sildenafil compared to control.
- Trial name
- SilHF-US (NCT03460470)
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Hartford Hospital
Systemic Arterial Hypertension, Hypertension Resistant to Conventional Therapy
Renin-angiotensin-aldosterone System Polymorphisms in Resistant Hypertension and Adverse Cardiovascular Events
Renin-angiotensin-aldosterone system (RAAS) polymorphisms influence 24h arterial pressure fluctuation. Resistant systemic arterial hypertension (RSAH) has an increased risk of end organ damage and unfavourable prognosis, whereas…
- Conditions
- Systemic Arterial Hypertension, Hypertension Resistant to Conventional Therapy, Myocardial Infarction, Stroke
- Trial name
- GENHART (NCT01173029)
- Testing
- Anti-hypertensive drug treatment
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- Universidade Gama Filho
Hypertension, Diabete Type 2
Pharmacists Interventions on Patients Diabetic, and Obese Patients in the UAE: Randomized Controlled Trials.
Hypertension, diabetes, and obesity are considered major risk factors for cardiovascular diseases and premature mortality worldwide. Furthermore, they have severe consequences on quality of life among patients.
- Conditions
- Hypertension, Diabete Type 2, Obesity, Pharmacist-Patient Relations
- Trial name
- NCT05488002
- Testing
- Pharmaceutical intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Primary Open Angle Glaucoma, Healthy Subjects
Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor
The objectives of this study are to assess the safety and effectiveness of the SENSIMED Triggerfish® (TF) device in continuous recording of relative fluctuation in intraocular pressure (IOP).
- Trial name
- NCT01390779
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Diabetes Mellitus, Hypertension
Community-based E-Health Program for Older Adults Living With Chronic Diseases
With increased aging population, there is a higher rate of having chronic diseases and cognitive impairment. In order to achieve successful aging, it is important for community-dwelling older adults to perform better…
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemias
- Trial name
- CeHP (NCT04560296)
- Testing
- Community-based E-Health Program, usual self-management and follow up with doctors/nurse
- Where
- 9 sites in Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Cognitive Function, Mediterranean Diet
Dietary Adherence and Cognitive Function in Older Adults
This study aimed to evaluate the relationship between adherence to the Mediterranean, DASH, and MIND diets and cognitive function in elderly individuals.
- Conditions
- Cognitive Function, Mediterranean Diet, Dietary Approaches to Stop Hypertension, Elderly Population
- Trial name
- NCT06631027
- Where
- Turkey (Türkiye)
- Volunteers
- 1,027 people
- Sponsor
- Ankara Yildirim Beyazıt University