Clinical trials: High Myopia, open to volunteers
High Myopia, Cataract
Shanghai High Myopia Study
The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of high myopic cataract and age-related cataract patients.
- Conditions
- High Myopia, Cataract, Visual Outcome, Genetic Anticipation
- Trial name
- NCT03062085
- Testing
- Cataract
- Where
- China
- Volunteers
- 60,000 people
- Sponsor
- Shanghai High Myopia Study Group
High Myopia, Pathologic Myopia
Shanghai Child and Adolescent Large-scale Eye Study -High Myopia Registration
1.1 Research objectives A．To observe the fundus changes in the posterior pole (morphology, thickness, asymmetry, blood flow density, etc) with the myopia progression.
- Trial name
- SCALE-HM (NCT03666052)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging
Shanghai Eye Study for Adults
Blindness and visual impairment severely impact the visual health and life quality of people, particularly the 2.566 million senior citizens aged at 65 and above in Shanghai.
- Trial name
- SESA (NCT03455478)
- Testing
- spectacles
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE
This prospective observational cohort study will investigate corneal biomechanical characteristics and their relationships with corneal stromal tissue features in adult patients undergoing clinically indicated small-incision…
- Trial name
- SMILE (NCT07906327)
- Testing
- SMILE
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji University
High Myopia
Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.
In this cross-sectionnal study the aim is to increase the understanding of posterior staphyloma through a unique European consortium.
- Trial name
- MYOFORTE (NCT06949579)
- Testing
- blood sampling for DNA
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Conventional LASIK, Femto-LASIK and PRK in Low and Moderate Myopia
Changes of Higher-Order Aberrations After Different Types of LASIK in Myopia
This prospective comparative interventional study will enroll patients with low and moderate myopia who seek laser vision correction at Sohag Center for LASIK and Corneal Surgeries, Sohag, Egypt.
- Trial name
- NCT06860061
- Testing
- Laser refractive surgery
- Volunteers
- 60 people
- Sponsor
- Sohag University
Myopia, Moderate, Myopic Astigmatism
A Prospective, Randomized Clinical Study of Two Phakic Toric Implantable Lenses
Primary Objective: To compare the efficacy and the residual refractive error of EYECRYLTM Phakic toric versus Visian® Toric ICL in moderate to high myopic patient with co-existing astigmatism.
- Conditions
- Myopia, Moderate, Myopic Astigmatism, Myopia, Degenerative
- Trial name
- NCT06839898
- Testing
- EYECRYLTM Phakic Toric Intraocular Lens Treatment Arm, Visian® Toric ICL Treatment Arm
- Where
- 4 sites in Germany, India
- Volunteers
- 172 people
- Sponsor
- Biotech Healthcare Holding Gmbh
High Myopia
Wuhan High Myopia Study
The study aims to observe the long-term changes of ocular（especially fundus） structure and visual function in patients with high myopia, so as to provide evidence for the prevention, diagnosis and prognosis of high myopia.
- Trial name
- LOVE-WH (NCT06162234)
- Testing
- observational
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Cataract
Comparing Monofocal IOLs in Highly Myopic Cataract Patients
Comparison of Postoperative Outcomes in Patients with High Myopia Undergoing Cataract Surgery Implanted with Extended Depth of Focus Intraocular Lens (ICB00) and Monofocal Intraocular Lens (ZCB00)
- Trial name
- NCT06905938
- Testing
- no intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
High Myopia
100 High Myopia Patient-reported Outcomes (PRO) and Performance Outcomes (PERFO)
Prospective, longitudinal, interventional, exploratory, non-randomized, single-center study including patients with pathological myopia .
- Trial name
- PPO100 (NCT07101146)
- Testing
- Quality of life questionnaire, Performance Outcomes (PerfO), Semi-structured interviews
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Myopia
Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye Drops
A multicenter, prospective, intervention study on the control of myopia in young children using high-order phase element array microstructure lenses (H.O.P.E.) in combination with low-concentration atropine eye drops (0.02%)
- Trial name
- NCT07846787
- Testing
- High-order Phase Element Array Microstructure Design Lens (H.O.P.E.), 0.02% Atropine Sulfate Eye Drops
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Ruihua Wei
Myopia, Refractive Ametropia
Comparison of Low- Versus High-Level Angle Kappa Compensation Strategies in SMILE Using the VisuMax 800: A Randomized Clinical Trial
The goal of this clinical trial is to compare two intraoperative kappa-angle compensation strategies during small incision lenticule extraction (SMILE) using the VisuMax 800 platform in patients with relatively large kappa-angle…
- Trial name
- NCT07512102
- Testing
- Apply high compensation to the Kappa angle., Apply low compensation to the Kappa angle.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
High Myopia
Comparison of Retinal Damage in ICL Implantation Using 3D Visualization System vs. Microscope
Implantable collamer lens (ICL) implantation is considered one of the most effective surgical treatments for high myopia. The procedure primarily involves adjusting the position of the ICL within the eye.
- Trial name
- NCT06966622
- Testing
- 3D visualization system with coaxial illumination, microscope with standard illumination
- Volunteers
- 40 people
- Sponsor
- Fuzhou Eye Hospital
High Myopia
SmoothCore Orthokeratology Plus M.O.V.E. Lenses vs. M.O.V.E. Lenses Alone for Myopia Control in Children With High Myopia
This clinical trial aims to determine whether a combination of overnight orthokeratology lenses and daytime myopia-control spectacles is more effective than myopia-control spectacles alone in slowing myopia progression and…
- Trial name
- NCT07854366
- Testing
- SmoothCore Technology Orthokeratology Combined with M.O.V.E. Lenses, M.O.V.E. Lenses Alone
- Volunteers
- 100 people
- Sponsor
- Beijing Tongren Hospital