Clinical trials: High Risk Drinking
Pain, Healthy
To Investigate Safety, Tolerability, and Pharmacokinetics of Treatment With BI 660848 Rising Single Doses (From 2 mg to 600 mg) Administered as Oral Drinking Solution (Powder in Bottle).
As a transition from preclinical investigations to clinical development in this first-in-human trial, safety, tolerability, and pharmacokinetics of BI 660848 will be assessed in human male volunteers using single rising oral…
- Trial name
- NCT01145014
- Testing
- BI 660848
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Alcohol Use, Unspecified
Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School
The purpose of the proposed research is to evaluate (1) whether a future possible self task (FPST) can lead to changes drinking identity (DI; how much one associates one's self with drinking) and (2) whether the FPST and changes…
- Trial name
- NCT06191861
- Testing
- Most hoped for future self, Most feared future self, Control (trip to zoo)
- Where
- United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections
The proposed study involves conducting a larger-scale study exploring Game Plan's effects among MSM in the real-world, alongside innovative approaches for expanding HIV testing.
- Trial name
- NCT04552171
- Testing
- Access to Game Plan app and 24-hour helpline
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Brown University
Sedation
The Impact of Long-term High-risk Drinking on the Effective Dose of Osselidin
this study aims to investigate the effect of chronic high-risk alcohol consumption on the effective dose of oliceridine combined with propofol for painless gastroscopy, so as to provide a reference for rational clinical…
- Trial name
- NCT07880899
- Testing
- long-term high-risk drinking, non-drinking
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol Drinking in College
Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention for High-risk Drinking University Students
The aims of this pilot study are: 1. To examine the factors associated with alcohol drinking and alcohol use disorder 2. To examine the effect of face-to-face alcohol brief intervention on drinking reduction 3.
- Trial name
- NCT03675373
- Testing
- Mobile chat-based instant messages, Alcohol brief intervention
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
HIV/AIDS
The Outreach and Prevention at ALcohol Venues in East Africa Study (OPAL-East Africa- Aim 2) (OPAL-Aim 2)
This study will evaluate the effect of a brief alcohol counseling intervention on PrEP and PEP adherence among adults with heavy alcohol use at high risk for HIV, while gaining insights into the facilitators, barriers, and…
- Trial name
- OPAL-Aim 2 (NCT06036238)
- Testing
- Healthy Living Intervention (HLI), Standard of Care
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Drinking
High Schools- High on Life: an Intervention to Reduce Excessive Drinking in Danish High Schools
High schools High on life' intervention is a high school-based, multi-component intervention guided by theory, evidence, and empirical findings to reduce excessive drinking among Danish high school students.
- Trial name
- NCT03906500
- Testing
- High schools High on Life
- Where
- Denmark
- Volunteers
- 3,682 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Alcohol Drinking, High-Risk Drinking Patterns
Clinical Effectiveness of a Motivational Interviewing-Based Conversational Mobile Application for High-Risk Drinkers
This study aims to evaluate and compare the degree of alcohol reduction between high-risk drinkers who use a motivational interviewing-based conversational agent (chatbot) application for four weeks and those in the control group…
- Trial name
- NCT07238998
- Testing
- Motivational Interviewing-Based Conversational Agent (Mobile Chatbot), No Intervention (Waitlist Control)
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Yonsei University
Heavy Drinking
Brief Mobile Intervention for Prepartying
The primary objective of the research study is to develop and test a prepartying (aka "pregaming") specific brief mobile app intervention that is intended to help college students reduce their prepartying drinking behavior.
- Trial name
- NCT04016766
- Testing
- Mobile app prepartying intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Drinking, Heavy Drinking
Reset Challenge: Reducing High-risk Drinking for Cancer Prevention
This is a single-arm, non-randomized, prospective study to evaluate the feasibility and preliminary efficacy of a 30-day mobile Health (mHealth) Reset Challenge for reducing high-risk drinking.
- Conditions
- Alcohol Drinking, Heavy Drinking, Binge Drinking
- Trial name
- NCT07591428
- Testing
- 30-Day Alcohol Abstinence Challenge
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Oklahoma
Alcohol Use Disorder, Family Members
Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19
This R01 project titled "Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19" is a Hybrid II RCT/implementation study to modify and test two of our alcohol smartphone…
- Conditions
- Alcohol Use Disorder, Family Members, Behavior, Addictive
- Trial name
- NCT05419128
- Testing
- PartnerCHESS, ACHESS
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of Wisconsin, Madison
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Game Plan for PrEP
This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their…
- Trial name
- NCT04973267
- Testing
- Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Brown University
Contraceptive Usage, Alcohol Use Complicating Childbirth
Native-Changing High-risk Alcohol Use and Increasing Contraception Effectiveness Study
Native CHOICES is a randomized controlled trial of an adapted intervention to reduce the risk of alcohol exposed pregnancies in American Indians and Alaska Natives (AI/ANs).
- Conditions
- Contraceptive Usage, Alcohol Use Complicating Childbirth, Alcohol Drinking
- Trial name
- Native-CHOICES (NCT03930342)
- Testing
- Native-CHOICES
- Where
- 2 sites in United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Washington State University
Alcohol Misuse
Mobile Alcohol Use Intervention
This study aims to examine the feasibility and acceptability of a mobile health intervention to reduce alcohol use and related consequences among young adults.
- Trial name
- NCT07126613
- Testing
- Mobile Health Intervention to Reduce Alcohol Use Among Young Adults
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Policy, Binge Drinking
Effect of High School Alcohol Policies on Students' Binge Drinking- a Natural Experiment
The aim of the project is to evaluate the effects of the introduction of new mutual alcohol policies in 30 high schools in 2017 on students binge drinking.
- Trial name
- NCT03704402
- Testing
- Alcohol policy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Aging, Alcohol Drinking
The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers
The goal of this pilot study is to explore a combination of two interventions: (1) a behavioral alcohol-reduction intervention using motivational interviewing, and (2) a blinded probiotic microbiome or placebo intervention.
- Trial name
- NCT07415707
- Testing
- Visbiome, Motivational Interviewing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Oxidative Stress
Drinking Effect of Electrolyzed Alkaline Reduced Water on Oxidative Stress and Fatigue After Intense Exercise
The goal of this clinical trial is to test the drinking effect of electolyzed alkaline reduced water (ARW) generated from alkaline ionizer (CGM MWPI-2101) on oxidative stress and fatigue after high-intensity exercise in healthy…
- Trial name
- NCT05673395
- Testing
- Electrolyzed alkaline reduced water generator
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kyu Jae Lee
Alcohol Drinking, Pregnancy
Alcohol Self-reporting During Pregnancy. AUTOQUEST Study.
The effects of alcohol consumption during pregnancy have been known for decades. However, alcohol consumption in pregnant women remains today a public health problem and its identification is primordial.
- Trial name
- AUTOQUEST (NCT04786587)
- Testing
- blood test, self-administered questionnaire
- Where
- France
- Volunteers
- 2,425 people
- Sponsor
- University Hospital, Lille
Drinking Behavior
A Social Media Intervention for Risky Drinking
This study is being completed to pilot prevention methods to promote wellness and reduce risky behaviors, including the use of substances such as alcohol and other drugs.
- Trial name
- NCT04721925
- Testing
- Social media messaging
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Michigan