Clinical trials: High Risk Non-cardiac Surgery
Surgery, Fluid Responsiveness
Superior Vena Cava Collapsibility Index for Predicting Fluid Responsiveness During High-risk Non-cardiac Surgery
The goal of this prospective study is to validate the superior vena cava collapsibility index (SVC-CI) as a predictor of fluid responsiveness during laparotomy and open aortic surgery.
- Conditions
- Surgery, Fluid Responsiveness, Transesophageal Echocardiography
- Trial name
- PRESCIENCE (NCT06188039)
- Testing
- Superior vena cava collapsibility index, PEEP elevation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Uniwersytecki Szpital Kliniczny w Opolu
Perioperative Myocardial Injury, Blood Pressure
NORepinephrine-Maintaining-individuaALIZEd Blood Pressure
This study compares the effect of individualized vs standard blood pressure management on postoperative myocardial injury in high-risk patients undergoing non-cardiac surgery by measuring the hs-cTnT levels.
- Conditions
- Perioperative Myocardial Injury, Blood Pressure, Non-cardiac Surgery
- Trial name
- NCT03715712
- Testing
- standardized blood pressure management, Individualized blood pressure management
- Where
- South Korea
- Volunteers
- 420 people
- Sponsor
- Seoul National University Hospital
High Sensitive Troponin T Release
Cardioprotection by Sevoflurane Preconditioning in Noncardiac Thoracic Surgery
It has been shown that the use of volatile anaesthetics, that are usually used to perform a general anesthesia, have cardioprotective properties.
- Trial name
- NCT02217319
- Testing
- Sevoflurane, TIVA
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Cardiac Surgical Procedures, High-risk Surgical Patient
A New Non-invasive Marker to Detect Silent Hypoxia in Patients Undergoing Cardiac Surgery
In patients undergoing cardiac surgery under cardiopulmonary bypass, some organs like brain and heart are preserved while others (skin, gut and skeletal muscle) are being underperfused.
- Conditions
- Cardiac Surgical Procedures, High-risk Surgical Patient, Anaerobic Threshold
- Trial name
- NCT01560611
- Testing
- Near infrared spectroscopy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Heart Diseases
Sternal Plating High Risk
Participants are being invited to participate in a research study at University Hospitals because they have heart disease and are scheduled for open heart surgery.
- Trial name
- NCT06660186
- Testing
- Rigid Sternal Fixation, Wire Cerclage
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University Hospitals Cleveland Medical Center
Hemodynamic Instability During Anesthesia, High Risk Surgery
Focused TTE for Hemodynamic Instable High Risk Patients
Focused transthoracic echocardiography (TTE) is a technique, which allows quick and non-invasive diagnosis and monitoring in hemodynamic instable patients.
- Trial name
- NCT01811914
- Testing
- intraoperative TTE
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Philipps University Marburg
Abdomen, Acute, Myocardial Injury After Non-cardiac Surgery
The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery
Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury…
- Conditions
- Abdomen, Acute, Myocardial Injury After Non-cardiac Surgery, Troponin I, Myocardial Injury
- Trial name
- NCT05992961
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 558 people
- Sponsor
- Nordsjaellands Hospital