Clinical trials: Hip Fracture Surgery
Hip Fractures
Surgical Treatment of Hip Fractures Under Peripheral Regional Anesthesia
The study investigates whether treatment of proximal femoral fractures is possible using a peripheral regional anesthesia technique.
- Trial name
- NCT04005404
- Testing
- Ropivacaine (sciatic nerve block), Ropivacaine (lumbar plexus block L2-L4), Ropivacaine (lumbar plexus block Th12-L1)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Helios Research Center
Femur Neck Fracture, Hip Fractures
Lumbar Erector Spinae Plane Block Versus PENG Block for Hip Fracture Surgery
The purpose of this clinical trial is to compare two different nerve block techniques-the Pericapsular Nerve Group (PENG) block and the Lumbar Erector Spinae Plane Block (L-ESPB)-for managing pain after hip fracture surgery in…
- Conditions
- Femur Neck Fracture, Hip Fractures, Postoperative Pain
- Trial name
- NCT07910487
- Testing
- Pericapsular Nerve Group Block, Lumbar Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Beni-Suef University
Delirium, Cognitive Dysfunction
Post-operative Delirium (POD) in Patients Undergoing Hip Fracture Surgery
The primary endpoint of the study is the appearance of Post Operative Delirium within the first 3 months. The secondary endpoints are the development of POCD, dementia of any type of new onset at 12 months, mortality at 30 days…
- Trial name
- NCT05105906
- Testing
- cognitive tests performed
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Femoral Fractures, Hip Fractures
Influence of Bone Strength Measured by DensiProbe on Bone Related Fixation Failure
Hip fractures mostly occur in elderly people with low bone strength. Bone strength is determined by bone mineral density (BMD), bone turnover, microarchitectural and geometrical properties of the bone.
- Conditions
- Femoral Fractures, Hip Fractures, Osteoporosis, Bone Density
- Trial name
- Densiprobe (NCT00822159)
- Testing
- DensiProbe Hip
- Where
- 8 sites in Austria, Germany and 2 more
- Volunteers
- 198 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Hip Fractures, Hip Disease
Safety Study of Dexmedetomidine in Elderly Under General Anesthesia
The purpose of this study is to find out appropriate dose range of dexmedetomidine to provide the elderly patients satisfactory sedation and analgesia with stable hemodynamics during perioperative period of hip replacement under…
- Trial name
- NCT05567523
- Testing
- Dexmedetomidine, Normal saline, Midazolam
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhenjiang First People's Hospital
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Alcohol Skin Solutions in Fractured Extremities
The prevention of infection is an important goal influencing peri-operative care of extremity fracture patients. Standard practice in the operative management of extremity fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture
- Trial name
- PREPARE (NCT03523962)
- Testing
- DuraPrep, ChloraPrep
- Where
- 27 sites in United States, Canada
- Volunteers
- 8,485 people
- Sponsor
- University of Maryland, Baltimore
Hip Fractures
Exercise Program and Follow-up in the Elderly After Hip Fracture Surgery Using a Digital Application.
Background In recent years, Western populations have experienced an increase in life expectancy and therefore an ageing population.
- Trial name
- NCT04919083
- Testing
- Program of Therapeutic Exercise and Functional Recovery, Standardised nursing care plan
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Zamar Fisioterapia
Hip Fractures
Nutritional Optimization and Bone Health Management for Older Adults Undergoing Hip Fracture Surgery
The overall objective of this pilot study is to test a comprehensive nutritional intervention in elderly patients diagnosed with hip fracture, which the study team believe will reduce functional decline, morbidity and mortality.
- Trial name
- NCT05971173
- Testing
- Juven, Centrum Silver 50+
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hip Fracture , Postoperative Mortality
Clinical Data-Driven AI Model for Mortality Prediction After Hip Fracture
Hip fractures are a major cause of morbidity and mortality, particularly in elderly patients. Accurate prediction of postoperative mortality is critical for risk stratification and clinical decision-making.
- Trial name
- NCT07495527
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Hip Arthroplasty, Hip Fracture Surgeries
Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia
Sacral erector spinae plane block(S-ESPB) has been recently described. Case reports are showing that it is useful in various types of surgery.
- Conditions
- Hip Arthroplasty, Hip Fracture Surgeries, Femoral Neck Fractures, Postoperative Pain
- Trial name
- NCT07442721
- Testing
- Sacral erector spinae plane block, PENG block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University Hospital
Chronic Renal Failure, Hip Fracture
Effects of Dexmedetomidine Premedication on Geriatric Patients With Chronic Renal Failure Undergoing Hip Surgery
Geriatric patients (age ≥ 65 years) undergo surgery for hip fractures that develops due to osteoporosis and falls. Dialysis-dependent chronic kidney disease is associated with an increased risk of cardiovascular comorbidity.
- Trial name
- NCT01837290
- Testing
- dexmedetomidine infusion for premedication, Midazolam, saline infusion
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Baskent University
Anaemia, Myocardial Ischaemia, Fractured Neck of Femur
Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur: An Observational Study Study Protocol: Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur
Blood transfusion is an expensive and finite resource and optimum transfusion threshold in surgical patients is yet to be defined.
- Trial name
- NCT02969811
- Volunteers
- 47 people
- Sponsor
- NHS Lothian
Hip Fractures
Audit of Hip Fractures Surgically Managed
Investigators are reviewing the the charts and medical records of participants who were operated at our institute from 2010 onward for hip fractures.
- Trial name
- NCT04187261
- Testing
- hip fracture surgeries
- Where
- Pakistan
- Volunteers
- 2,000 people
- Sponsor
- Aga Khan University
Postoperative Delirium
Study of Postoperative Delirium in Elderly People After Orthopedic Surgery
The purpose of this study is to investigate the possible relationship of microRNA and postoperative delirium.
- Trial name
- NCT02817386
- Testing
- interview
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Postoperative Delirium
The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Elderly Patients Undergoing Hip Fracture Surgery
To explore the effects of bupivacaine liposomes in preemptive analgesia for iliofascial block on postoperative pain and postoperative delirium in elderly patients with hip fractures, to optimize perioperative analgesia…
- Trial name
- NCT07066111
- Testing
- Tramadol, bupivacaine liposome (ultrasound-guided high iliofascial space block)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hip Fracture
Comparison of Three Analgesic Strategies for Hip Fracture Surgery
Hip fracture surgery is associated with significant postoperative pain and increased opioid requirements. Regional anesthesia techniques may improve analgesia and reduce opioid consumption.
- Trial name
- HIP-3B (NCT07676734)
- Testing
- Quadro-Iliac Plane Block, Suprainguinal Fascia Iliaca Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Elective Hip Fracture Surgery
Whey Intake Blood Glucose, Fasting, Thirst, Nausea and Vomiting Levels of Patients Undergoing Elective Hip Fracture Surgery
Whey Intake Blood Glucose, Fasting, Thirst, Nausea, Vomiting Elective Hip Fracture Surgery
- Trial name
- NCT06316648
- Testing
- whey intake group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Nutrition, Postoperative Pain
Relationship Between Fracture Type and Preoperative Nutritional Status with Postoperative Pain
The geriatric patient group is a population that should be considered differently than other age groups due to physiological characteristics that change with age.
- Conditions
- Nutrition, Postoperative Pain, Hip Fracture, Geriatric
- Trial name
- NCT06784089
- Testing
- Geriatric Nutrition Risk Index, visual analog scale
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Venous Thromboembolism, Embolism and Thrombosis
Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)
The purpose of this study is to determine whether TTP889 prevents venous thromboembolism following surgery to repair hip fracture.
- Conditions
- Venous Thromboembolism, Embolism and Thrombosis, Hip Fractures
- Trial name
- NCT00119457
- Testing
- TTP889
- Where
- 21 sites in Czechia, Denmark and 2 more
- Volunteers
- 300 people
- Sponsor
- vTv Therapeutics
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York