Clinical trials: Hip Osteoarthritis
Hip Osteoarthritis, Total Hip Arthroplasty
Clinical Phenotypes in Persons With Hip Osteoarthritis and Prognostic Factors for Outcome After Total Hip Arthroplasty
This prospective longitudinal cohort study aims (1) to identify clinical phenotypes in persons with hip osteoarthritis and after total hip arthroplasty, and (2) to identify prognostic factors for outcomes after total hip…
- Trial name
- HIPPROCLIPS (NCT05265858)
- Testing
- Total Hip Arthroplasty
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Osteoarthritis, Knee, Osteoarthritis, Hip
Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis
This is a phase 2 open-label, 6 arms (1 study group and 1 control group for each joint category), randomized control group clinical study with 300 subjects diagnosed with osteoarthritis of knees (n=100), hips (n=100) and…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Shoulder
- Trial name
- AdMSCs (NCT04448106)
- Testing
- Celltex- AdMSCs
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Celltex Therapeutics Corporation
Degenerative Joint Disease
Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty
To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain.
- Trial name
- DA THA pain (NCT02904993)
- Testing
- L2 paravertebral block, periarticular injection group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoarthritis, Arthroplasty
Mobility Assessment of Patients With Total Hip Arthroplasty
The purpose of this study is to describe the 3D joint biomechanics of the lower extremities of patients having had a total hip replacement or hip resurfacing surgery as compared to a healthy age and weight matched control group…
- Conditions
- Osteoarthritis, Arthroplasty, Hip Replacement
- Trial name
- NCT00664508
- Testing
- Motion analysis
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Primary Elective Hip Arthroplasty (THA), Primary Elective Total Knee Arthroplasty (TKA)
Digital Patient Journey Solution for Patients Undergoing Elective Hip and Knee Arthroplasty Dueto Primary Osteoarthritis
This is an interventional study which aims at assessing the effects of a digital patient journey solution in patients undergoing elective hip and knee arthroplasty due to primary osteoarthritis.
- Trial name
- NCT04083326
- Testing
- Digital Patient Journey Solution
- Where
- Finland
- Volunteers
- 69 people
- Sponsor
- VTT Technical Research Centre of Finland
Osteoarthritis, Hip
Effect of Anti-gravity Treadmill Training After Total Hip Arthroplasty
Background/Objectives: Total hip arthroplasty is one of the most common orthopedic procedures. When the surgery is successful and followed by high-quality physiotherapy, patients' quality of life usually improves and they return…
- Trial name
- NCT07170215
- Testing
- antigravity treadmill (ALTERG VIA, Lifeward CA, Inc., Milmont Drive, Fremont, CA, U-SA)
- Where
- Croatia
- Volunteers
- 34 people
- Sponsor
- University of Rijeka
Osteoarthritis Secondary, Osteoarthritis Primary
Transforming Rehabilitation: Personalised Care for a Better Quality of Life
General aim of the project: building and validating an Artificial Intelligence (AI)-based prediction model on rehabilitation outcomes (total joint replacement - TJR - of the hip and knee for primary and secondary osteoarthritis)…
- Conditions
- Osteoarthritis Secondary, Osteoarthritis Primary, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- PREPARE (NCT06249958)
- Testing
- Rehabilitation, Verticalisation
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Arthritis, Osteoarthritis, Knee
Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee Replacement
The study will describe the short-term effects the study drug, rivaroxaban, has on the body when a patient is switched from enoxaparin injection (by needle) to oral rivaroxaban (by mouth) for the prevention of blood clotting in…
- Conditions
- Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
- Trial name
- NCT01094886
- Testing
- Rivaroxaban
- Where
- 5 sites in United States
- Volunteers
- 56 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Legg Calve Perthes Disease
Perthes Disease in Norway
Calvé-Legg-Perthes disease (CLP) is a hip disease in children whose femoral head becomes completely or partially necrotic. The disease is most common in five-six years of age.
- Trial name
- NCT03885960
- Where
- Norway
- Volunteers
- 216 people
- Sponsor
- Oslo University Hospital
Total Hip Replacement, Hip Dislocation
How Spinopelvic Movements Affect Hip Function After Total Hip Arthroplasty
Our study aims to evaluate the effect of spinopelvic movement on hip functions in individuals who have undergone total hip arthroplasty (THA).
- Conditions
- Total Hip Replacement, Hip Dislocation, Hip Osteoarthritis
- Trial name
- THA (NCT06711042)
- Testing
- functional tests and radiographic analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ordu University
Primary Osteoarthritis, Secondary Osteoarthritis
Anthology Hip Replacement System - Orthopaedic Data Evolution Panel (ODEP) Surveillance Study
This clinical study will verify the clinical and radiographic performance of the prosthesis when used in human subjects over a period of 10 years. All complications will be documented.
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Avascular Necrosis, Primary Total Hip Replacement (THR)
- Trial name
- NCT04425603
- Testing
- Anthology Hip Replacement System
- Where
- 4 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Hip Osteoarthritis
Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis
Hip osteoarthritis is associated with joint pain, physical disability, decreased muscle strength and poor health status, and the most common cause for total hip arthroplasty.
- Trial name
- PROHIP (NCT04070027)
- Testing
- Total Hip Arthroplasty, Progressive Resistance Training
- Where
- 4 sites in Denmark
- Volunteers
- 109 people
- Sponsor
- Vejle Hospital
Osteoarthritis, Hip, Rheumatoid Arthritis
Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis
The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.
- Trial name
- OASEQ (NCT05278520)
- Testing
- Total hip arthroplasty
- Where
- 4 sites in Finland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Turku
Osteoarthritis, Hip
Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoarthritis
This is a two-part, multi-center, randomized, double-blind, placebo-controlled, parallel-group study in patients with hip OA. Approximately 70 patients will be enrolled in Part I and approximately 440 patients will be enrolled in…
- Trial name
- NCT03793010
- Testing
- FX006, Normal saline
- Where
- 32 sites in United States
- Volunteers
- 70 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of Recovery Following Hip Resurfacing or Total Hip Arthroplasty
The primary purpose of this study is to compare early functional outcomes in patients undergoing hip resurfacing and total hip arthroplasty with the M2a-Magnum™ using more objective measures of function.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Arthritis, Traumatic Arthritis
- Trial name
- NCT00585988
- Testing
- Hip Resurfacing System, M2a-Magnum™ Large Metal Articulation
- Sponsor
- Biomet Orthopedics, LLC
Osteoarthritis
Evaluation of DVD and Internet Decision Aids for Hip and Knee Osteoarthritis: Focus on Health Literacy
The purpose of this study is to advance the evidence base regarding methods for facilitating informed decisions among patients with knee and hip osteoarthritis by comparing DVD and online formats of decision aids for these…
- Trial name
- NCT01618097
- Testing
- DVD Decision Aid, Internet Based Decision Aid
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Duke University
Arthroplasty, Osteoarthritis
Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery Recovery
The purpose of this study is to assess the effectiveness of a preoperative muscle training program on hip or knee TJA (Total Joint Arthroplasty).
- Trial name
- NCT03483519
- Testing
- Rehabilitation, Standard of Care
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Educational Problems, Hip Arthroplasty
VR Simulation and Basic Skills in THA
This prospective randomised clinical trial aims to test if virtual reality (VR) simulation helps acquire basic surgical skills in total hip arthroplasty (THA) by medical students. The main question[s] it aims to answer are: 1.
- Conditions
- Educational Problems, Hip Arthroplasty, Osteoarthritis, Hip, Medical Students
- Trial name
- MD-VR-THA (NCT05807828)
- Testing
- VR simulation on basic THA skills
- Where
- Greece
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Osteoarthritis
An Effectiveness and Safety Study of Two Doses of Acetaminophen Extended Release Caplets in the Treatment of Osteoarthritis of the Hip or Knee
The purpose of this study is to determine the safety and effectiveness of 650 mg and 1300 mg acetaminophen extended release given three times a day for the relief of signs and symptoms of osteoarthritis of the hip or knee for a…
- Trial name
- NCT00240786
- Testing
- acetaminophen extended release
- Volunteers
- 483 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Coxarthrosis
Effects of the Sangvia Blood Collection System on Postoperative Infections in Orthopedic Patients
The purpose of this study is to compare the infection rate in patients receiving/not receiving their own blood, collected during surgery, during and after orthopedic surgery.
- Trial name
- NCT01725724
- Testing
- Autologous blood transfusion, Allogeneic blood transfusion
- Where
- 4 sites in Norway
- Volunteers
- 162 people
- Sponsor
- Haukeland University Hospital
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