Clinical trials: Hip Prosthesis
Adverse Reactions to Metal Debris, Infection of Total Hip Joint Prosthesis
Imaging of Joint Replacement Complications by PET/CT
Total hip replacement is the well-established surgical method for treatment of hip osteoarthritis and related diseases. The outcome of the procedure is commonly satisfactory and most patients will not need any revision surgery.
- Conditions
- Adverse Reactions to Metal Debris, Infection of Total Hip Joint Prosthesis, Mechanical Loosening of Prosthetic Joint
- Trial name
- Propeli (NCT01970228)
- Testing
- 68Ga-citrate and 18F-FDG PET/CT imaging
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Turku University Hospital
Indications for a Total Hip Prosthesis
Primary Birmingham Hip Resurfacing Arthroplasty Using a Metal-on-Metal Couple in the Young Active Patient
To prospectively obtain data about the clinical and radiological results of the resurfacing technique as primary hip prosthesis in young active patients
- Trial name
- NCT00285948
- Testing
- Primary Birmingham hip resurfacing arthroplasty using a metal-on-metal couple
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Hospital, Ghent
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees
The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT06194838
- Testing
- Ossur Power Knee, Reboocon Intuy Knee
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Liberating Technologies, Inc.
Hip Prosthesis Infection
Single-stage Surgery With Antibiotic-loaded Hydrogel Coated Implants Versus Two Stage Surgery for Secondary Prevention of Complex Chronic Periprosthetic Hip Joint Infection
Each year, around 1500 infected Total Hip Arthroplasties (THA) need non-conservative surgery, remaining an issue for patients and healthcare units.
- Trial name
- SINBIOSE-H (NCT04251377)
- Testing
- Defensive Antiadhesive Coating DAC®, Novagenit SRL
- Where
- 14 sites in France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Advanced Degeneration of the Hip Joint, Revision of the Hip Joint
Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA
The purpose of this study is to assess the safety and effectiveness of the OR3O™ Dual Mobility System. The study will evaluate the outcome of the Total Hip Arthroplasty using the OR3O™ Dual Mobility System over a ten year period.
- Trial name
- OR3O (NCT04325022)
- Testing
- Primary Total Hip Arthroplasty, Revision Total Hip Arthroplasty
- Where
- 12 sites in United States, Australia and 2 more
- Volunteers
- 177 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis, Hip, Arthropathy of Hip
Evaluation of Cemented and Cementless Fixation of Dual-mobility Hip Prosthesis in Elderly Patients With Osteoarthritis
The aim of this project is to investigate prosthesis fixation in the bone, respectively cemented and uncemented operation method of Avantage® dual-mobility acetabular cup in elderly patients, wear of the plastic in dual-mobility…
- Trial name
- NCT02404727
- Testing
- cup fixation, Avantage® Cup
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Arthritis, Osteoarthritis, Knee
Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee Replacement
The study will describe the short-term effects the study drug, rivaroxaban, has on the body when a patient is switched from enoxaparin injection (by needle) to oral rivaroxaban (by mouth) for the prevention of blood clotting in…
- Conditions
- Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
- Trial name
- NCT01094886
- Testing
- Rivaroxaban
- Where
- 5 sites in United States
- Volunteers
- 56 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Osteoarthritis, Hip, Hip Osteoarthritis
Clinical and Functional Outcome of the MobileLink Acetabular Cup System in the Short-, Mid-, and Longterm Follow-up
The implantation of artificial hip joints is one of the most frequently performed surgeries. Normally, patients are very satisfied with the results. The MobileLink hip prosthesis system is a CE marked medical device.
- Conditions
- Osteoarthritis, Hip, Hip Osteoarthritis, Prosthesis Survival, Prosthesis Failure
- Trial name
- NCT04688593
- Testing
- MobileLink
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 520 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Osteoarthritis, Hip
Evaluation of a Short Femoral Stem in Total Hip Arthroplasty
In recent years, short femoral stems have been introduced. Short stems are designed based on traditional stems with good clinical results.
- Trial name
- NCT02743208
- Testing
- Short stem hip arthroplasty (SHA), Total hip arthroplasty (THA)
- Sponsor
- St. Olavs Hospital
Clinic Hip Osteoarthrosis
Total Hip Prosthesis Assisted by Computer
Computer assistance in prosthetic hip surgery is able to improve the accuracy of the surgery: Associating hip navigation and EOSTM imaging pre-operatively could simplify the procedure of hip navigation in lateral decubitus while…
- Trial name
- NAVEOS (NCT01613989)
- Testing
- Prosthetic hip surgery, operated under manual control, Prosthetic hip surgery operated under navigation based on EOS imaging
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Bordeaux
Total Hip Arthroplasty, Survival, Prosthesis
Multicenter Mpact DM France
The primary objective of the study is to evaluate the 10-year performance of the MPACT DM cup in the treatment of patients requiring total hip arthroplasty.
- Trial name
- NCT05818891
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Medacta International SA
Infection of Total Hip Joint Prosthesis
Evaluating Advantages of Prevena After Hip and Knee Arthroplasty
Determine the extent to which application of the Prevena vacuum system to clean surgical incisions immediately following surgical procedure (total hip or total knee arthroplasty) will reduce the rates of: readmission to hospital…
- Trial name
- NCT01854138
- Testing
- Prevena Incision Management System
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- ProMedica Health System
Osteolysis, Arthroplasty Complications
Plasmafit® Revision Structan® Hip Endoprosthesis Cup
The aim of this observational study is to collect clinical and radiological results of the new Plasmafit® Revision Structan® Hip Endoprosthesis Cup in a standard patient population and when used in routine clinical practice.
- Conditions
- Osteolysis, Arthroplasty Complications, Instability of Prosthetic Joint, Degenerative Osteoarthritis
- Trial name
- NCT04255966
- Testing
- Plasmafit® Revision Structan®
- Where
- 4 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Prosthesis-Related Infections
Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty
The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative…
- Trial name
- NCT01760863
- Testing
- Oral Antibiotics
- Where
- 4 sites in United States
- Volunteers
- 185 people
- Sponsor
- Rush University Medical Center
Orthopedic Surgery, Total Hip Prosthesis
Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring - COGNIDES
The recovery of cognitive and psychomotor functions is best performed under anesthesia after desflurane when propofol in that obtaining a Aldrete score> 8/10 output of the allowing SSPI.
- Conditions
- Orthopedic Surgery, Total Hip Prosthesis, Total Knee Replacement
- Trial name
- Cognides (NCT02036736)
- Testing
- Intraoperative anesthetic strategy by Propofol, Intraoperative anesthetic strategy by Desflurane
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Improve Quality of Life
Exercise Program After Total Hip and Knee Replacement: a Randomized Controlled Trial
Randomized controlled trial. Patients will be enrolled at the moment of the pre-surgery assessment after verifying the inclusion/exclusion criteria and signing written informed consent.
- Trial name
- PAIR (NCT04761367)
- Testing
- Physical activity. Physical Activity program is performed in a group in a gym
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Hip Arthritis
Post Market, Retrospective Study to Evaluate Patients Implanted With Medacta Versafit Cup DM ™️ 2 Years Post-op
This is a post-market, retrospective with one prospective visit, multi- center study, designed to assess the clinical outcomes, surgical details including Anterior or Posterior surgical approach, and collect all complication data…
- Trial name
- NCT03897387
- Where
- 3 sites in United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Hip Arthropathy
Prospective and Obsevational Study of Total Hip Prothesis: HYPE Stem
The purpose of this study is to validate the performance and the safety of the HYPE (SERF) prothesis in compliance with the 93/42/EEC directive and in relation to the recommendations of the MEDDEV 2.7.1 guide ( guideline for…
- Trial name
- NCT05560022
- Where
- France
- Sponsor
- Societe dEtude, de Recherche et de Fabrication
Degenerative Osteoarthritis, Rheumatic Arthritis
CoreHip - Post Market Clinical Follow-Up Study
The study is designed as a prospective, non-interventional multicentre cohort study. The product under Investigation will be used in Routine clinical practice and according to the authorized Instructions for Use (IfU).
- Conditions
- Degenerative Osteoarthritis, Rheumatic Arthritis, Fractures, Hip, Necrosis, Femur Head
- Trial name
- NCT03685110
- Testing
- CoreHip Total Hip Arthroplasty
- Where
- 6 sites in Germany, Switzerland
- Volunteers
- 248 people
- Sponsor
- Aesculap AG
Non-inflammatory Joint Diseases
Metal on Metal Versus Ceramic on Metal Hip Replacement
The purpose of this study is to compare the performance of artificial hips with metal heads and metal sockets to artificial hips with ceramic heads articulating with metal socket components.
- Trial name
- NCT00208494
- Testing
- Total Hip Replacement
- Where
- 9 sites in United States, Canada
- Volunteers
- 392 people
- Sponsor
- DePuy Orthopaedics