Clinical trials: Hip Replacement, Total
Osteoarthritis
Fixation of OsseoTi™ Porous Structure Versus PPS (Porous Plasma Spray) Coating on the G7™ Acetabular Component for Primary Total Hip Arthroplasty
The primary objective of this project is to investigate, using RSA, acetabular implant migration of the OsseoTi™ G7 acetabular cup in comparison to conventional PPS coated G7 acetabular cup, and compare liner wear of thinnest…
- Trial name
- NCT02316704
- Testing
- THA with G7 PPS coted acetabular component, THA with G7 OsseoTi coted acetabular component
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 98 people
- Sponsor
- Hvidovre University Hospital
Venous Thromboembolism
Rivaroxaban (10mg) Given Once Daily in Patients Undergoing Total Hip Replacement Compared to Enoxaparin
The purpose of this study is to assess if 10 mg BAY 59-7939, taken once daily as a tablet, is safe and prevent blood clot which may form after total hip replacement operation.
- Trial name
- NCT00329628
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 215 sites in United States, Argentina and 26 more
- Volunteers
- 4,541 people
- Sponsor
- Bayer
Osteoarthritis, Hip Dislocation
Supine Sleeping After Total Hip Replacement
Aim of the current study is to test the non-inferiority hypothesis of differences in early hip dislocation between a group of patients who will be restricted to sleep in supine position and a group without restricted sleeping…
- Trial name
- NCT02107248
- Testing
- Sleep position: no restrictions, Sleep position: supine
- Where
- Netherlands
- Volunteers
- 456 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Arthritis of Hip, Fracture of Femur
Medial Wedge Insoles to Improve Gait in Persons After Total Hip Replacement
The study will test the hypothesis, that the use of medial wedge insoles in people participating in comprehensive rehabilitation between 1-6 months after total hip replacement, and not having a varus deformity of the knee or…
- Conditions
- Arthritis of Hip, Fracture of Femur, Aseptic Necrosis, Dysplasia; Hip
- Trial name
- NCT05736016
- Volunteers
- 100 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Avascular Necrosis of Hip, Degenerative Hip Joint Disease
Revision Total Hip Replacement Arthroplasty and Hematologic Variables
Revision total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative…
- Trial name
- NCT02951741
- Testing
- RTHRA group
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Bundang Hospital
Pain, Postoperative
Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-Containing Solutions in Post-Surgical Hip Replacement Pain
The aim of the study is to evaluate the therapeutic efficacy, safety and local tolerability of two different paracetamol-containing solutions in postoperative total hip replacement.
- Trial name
- NCT00508495
- Testing
- Paracetamol (acetaminophen), Paracetamol 1% solution, 0.9% sodium chloride solution
- Where
- 8 sites in Hungary
- Volunteers
- 148 people
- Sponsor
- Baxter Healthcare Corporation
Postoperative Analgesia After Unilateral Hip Arthroplasty
Efficacy and Safety of TRD205 Tablets for Postoperative Analgesia in Unilateral Total Hip Arthroplasty (Phase IIb)
This is a phase IIa, multicenter ,randomized, double-blind, Double-Dummy, Active- and placebo-controlled study designed to evaluate the efficacy, safety and kinetic characteristics of TRD205 tablets for postoperative analgesia…
- Trial name
- TRD205 (NCT07543796)
- Testing
- TRD205 Tablets, oral; 400 mg initial dose, then 200 mg q12h for 3 doses; total 4 doses, TRD205 Tablets, oral; 800 mg initial dose, then 400 mg q12h; total 4 doses, TRD205 Tablets, oral; 1200 mg initial dose, then 600 mg q12h; total 4 doses
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Tide Pharmaceutical Co., Ltd
Femur Neck Fracture, Arthroplasty Complications
Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA
After total hip arthroplasty using an 'Modular Dual Mobility' acetabular cup, which is effective in reducing the risk of dislocation, one of the serious complications occurring after total hip arthroplasty, the blood metal ion…
- Trial name
- NCT05181566
- Testing
- Total hip replacement arthroplasty using modular dual mobility cup, Total hip replacement arthroplasty using conventional acetabular cup
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Osteoarthritis
Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty
The primary objectives of the study is to compare gait kinematics and the return to normalization of gait in patients that have undergone a Total Hip Arthroplasty (THA) via the direct anterior approach versus the posterior…
- Trial name
- NCT00951951
- Testing
- Anterior Approach, Posterior Approach
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- Medacta USA
Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA)
Study to Evaluate the Safety and Efficacy of OR3O™ Dual Mobility System vs. Conventional Single Bearing Design Total Hip System
The purpose of this study is to compare OR3O™ Dual Mobility System to a conventional, single-bearing design Total Hip System in subjects who undergo Primary THA.
- Conditions
- Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA), Femoral Neck Fractures, Avascular Necrosis of Femoral Head
- Trial name
- OR3O (NCT04941729)
- Testing
- OR3O™ - Dual Mobility System, Conventional
- Where
- 4 sites in China
- Volunteers
- 24 people
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Hip Arthroplasty Replacement, Gait Biomechanics
Powered Impaction and Broaching in Elderly Total Hip Arthroplasty
Placing the parts of a hip replacement requires substantial force. This can lead to additional stress on the surgeon as well as the bone. A device was developed to help reduce this stress.
- Conditions
- Hip Arthroplasty Replacement, Gait Biomechanics, Surgeon Physiologic Stress
- Trial name
- NCT07747831
- Testing
- Total Hip Replacement with Automatic impaction and broaching device, Total Hip Replacement
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis, Hip, Arthropathy of Hip
Evaluation of Cemented and Cementless Fixation of Dual-mobility Hip Prosthesis in Elderly Patients With Osteoarthritis
The aim of this project is to investigate prosthesis fixation in the bone, respectively cemented and uncemented operation method of Avantage® dual-mobility acetabular cup in elderly patients, wear of the plastic in dual-mobility…
- Trial name
- NCT02404727
- Testing
- cup fixation, Avantage® Cup
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoarthritis, Hip
Whole Blood Metal Ion Concentrations in Metal-on-metal Total Hip Arthroplasty and Hip Resurfacing
The investigators aimed to investigate the possible differences in metal ion concentrations in patients following one of two types of metal-on-metal articulating hip prosthesis regarding chromium and cobalt concentration…
- Trial name
- NCT04585022
- Testing
- Magnum, Zimmer Biomet, Warsaw, IN, Recap, Zimmer Biomet, Warsaw, IN
- Volunteers
- 75 people
- Sponsor
- Hvidovre University Hospital
Developmental Dysplasia of the Hip
AI-assisted Preoperative Planning Technology for THA for DDH
In this study, the investigators retrospectively collected DDH case data of THA assisted by AI 3D planning and THA assisted by traditional planning.
- Trial name
- NCT05929105
- Testing
- artificial intelligence (AI)-assisted three-dimensional preoperative planning technology, X-ray film template for 2D planning
- Where
- China
- Volunteers
- 61 people
- Sponsor
- General Hospital of Ningxia Medical University
Osteoarthritis, Avascular Necrosis
A Clinical Evaluation of Metal Ion Release From Metal-on-Metal Cementless Total Hip Arthroplasty
A clinical Evaluation to determine metal ion release from 4th generation metal-on-metal hip articulating surfaces in cementless total hip arthroplasty.
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT00757354
- Testing
- Metal on Metal cementless hip
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Zimmer Biomet
Arthritis of Hip
Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty
The fascia iliaca compartment block (FICB) is a regional block that anesthetizes the femoral, obturator, and lateral femoral cutaneous nerves around the hip.
- Trial name
- NCT03375112
- Testing
- Fascia iliaca compartment block, Bupivacaine
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Henry Ford Health System
Osteoporosis
Early Effects of Parathyroid Hormone (PTH) on the Proximal Femur
Teriparatide is a potent osteoporosis medication that helps prevent fractures, however, the investigators know little about its effect on the hip.
- Trial name
- NCT01309399
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Health Research, Inc.
Coxarthrosis
10 Year Clinical Evaluation of Primoris Hip Component
Using the traditional and hitherto used uncemented hip prostheses achieved good clinical results, but one of the drawbacks is the risk of fracture in the femoral shaft in indbankning of the prosthesis (1-2%).
- Trial name
- Primoris (NCT01326832)
- Testing
- Primoris
- Where
- 2 sites in Denmark
- Volunteers
- 350 people
- Sponsor
- Zimmer Biomet
Hip Arthroplasty
Hospital for Special Surgery Hip Arthroplasty Cohort
Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk.
- Trial name
- NCT00454506
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis
Mindfulness Meditation for Surgical Pain and Anxiety
Health care professionals are dedicated to the ongoing evaluation of the peri-operative experience, and always striving to improve patient satisfaction.
- Trial name
- NCT04932499
- Testing
- Standard of Care, Mindfulness Meditation
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Calgary
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