Clinical trials: Hip Replacement, Total
Osteoarthritis, Hip, Femur Head Necrosis
Prophylaxis of Deep Vein Thrombosis Following Total Hip Arthroplasty
This prospective study compares an oral direct factor Xa inhibitor with LMWH for thromboprophylaxis in the patients undergoing THA.
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures
- Trial name
- NCT02379663
- Testing
- Rivaroxaban, Enoxaparin, Normal saline
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Primary Total Hip Arthroplasty
Opioid Free Anesthesia in Total Hip Arthroplasty
Total hip arthroplasty (THA) is one of the most common orthopedic surgical procedure and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- OFATHA (NCT05072704)
- Testing
- Sufentanil, Dexmedetomidine
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CMC Ambroise Paré
Postoperative Complications
Management of Patients on Long Term Anticoagulation Therapy Undergoing a Primary Total Hip of Knee Replacement
It is a multicenter, prospective, observational study of standard care. This study analyses the care of patients on long term effective anticoagulation therapy (ADELC) during a primary hip or knee arthroplasty.
- Trial name
- ADELC (NCT02714673)
- Testing
- anticoagulation
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Association pour le Développement et l'Enseignement de la Chirurgie Réparatrice et Orthopédique
Closed Reduction, Arthroplasty, Replacement, Hip
Associations Between Time to Reduction and Complications in Patients With Dislocated Total Hip Arthroplasty
The aim of the study is to investigate the impact of time to closed reduction on both patient related and organizational factors.
- Conditions
- Closed Reduction, Arthroplasty, Replacement, Hip, Length of Stay
- Trial name
- NCT07132723
- Testing
- Time in minutes from admission to closed reduction
- Where
- Denmark
- Volunteers
- 3,700 people
- Sponsor
- Nordsjaellands Hospital
Pain Management, Opioid Consumption
Opioid-Sparing Joint Replacement
The goal of this clinical trial is to evaluate whether an opioid-sparing postoperative pain regimen can reduce opioid consumption and maintain effective pain control in adults undergoing anterior total hip arthroplasty for…
- Trial name
- NCT07348627
- Testing
- Oxycodone 5 mg, Multimodal Non-Opioid Analgesia
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Emory University
Joint Disease
Evaluate the Effect of Osteo Introducer System in Total Hip Arthroplasty
Osteo introducer system is the instruments used in minimal invasive THA. This study will compare the minimal invasive THA using the osteo introducer system and THA using common instruments, to show the non-inferiority of osteo…
- Trial name
- NCT03113591
- Testing
- Minimum invasive total hip arthroplasty, Common total hip arthroplasty
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Suzhou MicroPort OrthoRecon Co. LTD
Hip Arthroplasty
Differentiation of Aseptic From Septic Loosening by 18F-fluoride PET
In this study, the investigators utilized the 18F-fluoride PET method to evaluate THA cases with a stable, septic or septic loosened implant in order to differentiate these clinical settings using a novel uptake type…
- Trial name
- NCT01017562
- Where
- Japan
- Volunteers
- 61 people
- Sponsor
- Yokohama City University Medical Center
Total Hip Arthroplasty
Analgesic Effect of the QLB-3 for Patients Undergoing a Total Hip Surgery
Total hip arthroplasty (THA) is one of the main elective orthopedic surgery. Recent studies have proven that patients undergoing an elective THA who are part of a fast track surgery program including an opioid free anesthesia…
- Trial name
- QLB-3 (NCT04555291)
- Testing
- Ropivacaine injection, NACL
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Primary Osteoarthritis Requiring Total Hip Replacement
Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)
Postoperative pain following total hip arthroplasty (THA) (1) is often considered moderate to severe and can therefore influence the postoperative course of event and result in delayed postoperative mobilization and prolonged…
- Trial name
- HÖFTPLASTIK (NCT01281891)
- Testing
- LIA, I/T morphine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Örebro County
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck
Z1 Hip System: Post-Market Clinical Follow Up Study
The objectives of this study are to confirm the early to mid- term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi- and primary total hip arthroplasty.
- Conditions
- Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
- Trial name
- NCT07104279
- Testing
- Z1 Femoral Hip System
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Hip Osteoarthritis
Mirogabalin for Total Hip Arthroplasty
The purpose of this study is to confirm the analgesic effect of mirogabalin in patients undergoing unilateral hip arthroplasty.
- Trial name
- NCT05938088
- Testing
- Arm I (mirogabalin group)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Gangnam Severance Hospital
Arthroplasty, Replacement, Hip, Exercise Therapy
Walking Skill Training Program Effects in Patients With Total Hip Arthroplasty
Rehabilitation plays an important part after total hip arthroplasty. In this common practice few studies have been performed on this issue. The aims of this study were: 1.
- Trial name
- NCT00808483
- Testing
- Walking skill training program
- Where
- Norway
- Volunteers
- 68 people
- Sponsor
- University of Oslo
Hip Arthrosis, Femur Head Necrosis
Difference in Return to Sports Activity After Hip Arthroplasty by THR or Resurfacing
This study aims to evaluate the return to activity in younger patients under 50 years old after undergoing either total hip replacement (THR) or hip resurfacing, as performed in everyday practice.
- Trial name
- PTH-50 (NCT06410079)
- Testing
- total hip replacement
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Société Française de chirurgie de la Hanche et du Genou
Nausea
Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery
The study aims to compare the incidence of side effects caused by Oxycodone and Hydromorphone.
- Trial name
- NCT02295124
- Testing
- Oxycodone, Hydromorphone
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Hip Osteoarthritis, Blood Loss
Comparison of Blood Loss Following Total Hip Arthroplasty With the Use of Three Thromboprophylactic Regimes: Dabigatran, Enoxaparin and Rivaroxaban.
The purpose of this study is to determine which of the following drugs: enoxaparin, dabigatran and rivaroxaban causes least blood loss after total hip replacement (THR).
- Trial name
- NCT02085824
- Testing
- Enoxaparin, rivaroxaban, dabigatran
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Centre of Postgraduate Medical Education
Arthoplasty, Nutrition
Effects of Preoperative Whey Protein and Exercise Support on Recovery After Total Hip Arthroplasty
Objective: The aim of this project is to evaluate the effects of preoperative whey protein supplementation and a physical exercise program on postoperative recovery outcomes in patients undergoing total hip arthroplasty (THA).
- Conditions
- Arthoplasty, Nutrition, Geriatric Assessment, Exercise Training
- Trial name
- THA (NCT07329010)
- Testing
- Preoperative Whey Protein and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- TC Erciyes University
Total Hip Replacement
Rehabilitation of Patients After THR - Based on Patients´Selfrated Health
Objective: The investigators hypothesized that all areas of health status after total hip replacement could be improved in patients aged over 65 years and over by using telephone support and counselling 2 and 10 weeks after…
- Trial name
- Rehab-THR (NCT02644096)
- Testing
- counselling and support after discharge from hospital
- Volunteers
- 175 people
- Sponsor
- University of Aarhus
Venous Thromboembolism
Pharmacokinetic (PK) Assessment of BIBR 1048 in Patients After Primary Elective Total Hip Replacement Surgery
To determine the PK profile of a single dose 150 mg BIBR 1048, oral capsule, administered 1-3 hours post surgery in hip replacement patients.
- Trial name
- NCT02170935
- Testing
- BIBR 1048 capsule
- Volunteers
- 62 people
- Sponsor
- Boehringer Ingelheim
Venous Thrombosis, Deep, Arthroplasty Complications
Selective Thromboembolism Prophylaxis After Arthroplasty
Asian populations have a lower rate of high-risk gene mutations of venous thrombosis, which means a reasonable perioperative anticoagulant management after hip or knee arthroplasty for Caucasian populations may be too excessive…
- Trial name
- NCT03804697
- Testing
- selective anticoagulation
- Volunteers
- 197 people
- Sponsor
- Guangdong Provincial People's Hospital
Hip Arthropathy
Observational Ambispective Study on HYPE Cups Associated With HIPER Liner
This study intend to collect data on total hip arthroplasty performed with HYPE cups used with conventional polyethylene liner (HIPER).
- Trial name
- NCT06465940
- Testing
- Total hip arthroplasty
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Societe dEtude, de Recherche et de Fabrication
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