Clinical trials: Hip Replacement, Total
Total Hip Arthroplasty
Rehabilitation After Direct Anterior Approach for Total Hip Arthroplasty
The causes for total hip arthroplasty (THA) in Taiwan include ischemic necrosis of the femoral head and degenerative osteoarthritis.
- Trial name
- NCT06356116
- Testing
- Usual care, Accelerated rehabilitation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Venous Thromboembolism, Arthroplasty, Replacement
Pradaxa (Dabigatran Etexilate) VTE Prevention After Elective Total Hip or Knee Replacement Surgery
an open, prospective, observational study to collect data on safety (major bleeding events) and efficacy (symptomatic venous thromboembolism(VTE)) of a switch from Enoxaparin to dabigatran etexilate in patients with total knee…
- Trial name
- NCT01153698
- Testing
- dabigatran
- Where
- 7 sites in Austria
- Volunteers
- 167 people
- Sponsor
- Boehringer Ingelheim
Arthroplasty, Replacement, Hip
The Comparison of 32mm and 28mm Head Components in Alumina-alumina Total Hip Arthroplasty
It has been postulated that use of a larger femoral head could reduce the risk of dislocation after total hip arthroplasty, but only limited clinical data have been presented in third generation alumina bearings.
- Trial name
- THA (NCT01098604)
- Testing
- 32mm ceramic head group, 28mm ceramic head group
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Bundang Hospital
Arthroplasty, Replacement, Hip
MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve
Revision total hip replacement using a ceramic head utilizes a titanium sleeve which introduced another articulation into the system that may lead to a local soft tissue reaction.
- Trial name
- NCT05686915
- Testing
- MARS MRI, Titanium Labs, Cobalt Labs
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Colorado Joint Replacement
Perioperative Hypothermia
Prospective Trial of the Effect of Preoperative Forced-air Warming on Perioperative Body Temperature Following Neuraxial Anesthesia in Total Hip Arthroplasty Patients
The purpose of this study is to determine if placement of a forced-air warming device prior to institution of regional anesthesia improves perioperative temperature control in patients undergoing total hip arthroplasty.
- Trial name
- NCT01626690
- Testing
- Bair-Paws Warming Device, Bair-Hugger Warming Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Coxarthritis
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular Resection Versus Capsular Flap Retention
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular resection versus capsular flap retention. Prospective study design comparing clinical data in randomized THA patients who either had capsular resection or…
- Trial name
- NCT02970253
- Testing
- Capsular resection, Capsular retention
- Where
- Belgium
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- ZOL
Prevention, Venous Thromboembolism
A Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty
The objective of this study is to assess the efficacy and safety of DU-176b compared with enoxaparin sodium for the prevention of venous thromboembolism in patients after elective total hip arthroplasty.
- Trial name
- NCT01181167
- Testing
- edoxaban, enoxaparin sodium
- Where
- 2 sites in Japan
- Volunteers
- 610 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Lumbar Erector Spinae Plane Block, Fascia Iliaca Block
Lumbar Erector Spinae Plane Block vs Fascia Iliaca Block vs Lumbar Plexus Block for Postoperative Analgesia for Total Hip Arthroplasty
This study aims to compare lumbar erector spinae plane block, fascia iliaca block, and lumbar plexus block for postoperative analgesia for hip surgery.
- Conditions
- Lumbar Erector Spinae Plane Block, Fascia Iliaca Block, Lumbar Plexus Block, Analgesia
- Trial name
- NCT06573931
- Testing
- Lumbar Erector Spinae Plane Block, Fascia Iliaca Block, Lumbar Plexus Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Osteoarthritis, Hip
Prolonged Multimodal Analgesia for Post-Discharge Pain Control After Primary Total Hip Arthroplasty
This is a prospective, three-arm, comparative study with a provider-crossover design. The first arm will comprise the standard of care pain regimen after discharge, which comprises PRN oxycodone, tramadol, and acetaminophen.
- Trial name
- NCT03358888
- Testing
- Multi-modal with as needed opioids, Multi-modal with one week of opioids offered, Standard of Care
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Rothman Institute Orthopaedics
Arthropathy of Hip
Evaluation of Implant Survival in Patients With a Pinnacle Ultamet Device in Conventional Total Hip Joint Replacement
The objective is to evaluate the implant survival rate for patients implanted with a PINNACLE® ULTAMET™ Metal-on-Metal implant for conventional total hip arthroplasty for the treatment of a severe hip disease and true femoral…
- Trial name
- NCT01684631
- Testing
- Total Hip arthroplasty
- Where
- 6 sites in France
- Volunteers
- 107 people
- Sponsor
- DePuy International
Blood Loss
Evaluating the Use of Tranexamic Acid (TXA) in Total Joint Arthroplasty
This research study aims to study the use of tranexamic acid (TXA) in total joint replacement (arthroplasty) of the hip (THR) and knee (TKR).
- Trial name
- NCT03825939
- Testing
- Intravenous Tranexamic Acid
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- NYU Langone Health
Hip Replacement Surgery
Efficacy and Safety of Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D) for Hemostasis in Subjects Undergoing Total Hip Replacement
The purpose of the study is to monitor the safety of FS VH S/D and evaluate whether FS VH S/D is superior to standard treatment in reducing blood loss in subjects undergoing total hip replacement with cement-free hip prostheses.
- Trial name
- NCT00161902
- Testing
- Fibrin Sealant Vapor-Heated Solvent/Detergent-treated
- Where
- 7 sites in Austria, Germany and 1 more
- Sponsor
- Baxter Healthcare Corporation
Osteoarthritis, Hip, Blood Loss
Bipolar Sealer for Reduction of Blood Loss in Anterior Total Hip Arthroplasties
The overall objectives and purpose of this study is to show that the Smith and Nephew Werewolf Fastseal 6.0 Bipolar Sealer is an effective tool to aide the surgical team in providing significant hemostasis during anterior total…
- Trial name
- NCT05356637
- Testing
- Werewolf Fastseal 6.0
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- North Texas Medical Research Institute, PLLC
Arthropathy of Hip
Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior Approach
Find the impact of supra-inguinal fascia iliaca compartment block on postoperative pain management after total hip arthroplasty by posterior surgical approach
- Trial name
- NCT04574479
- Testing
- Supra-inguinal fascia iliaca compartment block, Multimodal analgesia and PCA morphine pump
- Where
- Belgium
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Liege
Osteoarthritis, Hip
Clinical Investigation Comparing Two Different Ultra-porous Coated Surfaces of Uncemented Cups
A randomised controlled study comparing two types of ultra-porous coated uncemented cups in total hip arthroplasty. Primary objective is to investigate if the clinical, radiological and patient-reported outcome of the new…
- Trial name
- NCT05773261
- Testing
- MobilLINK TrabecuLINK cup, Pinnacle Gription cup
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Osteoarthritis, Hip, Hip Osteoarthritis
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty: A Randomized Double-Blind Trial
his study will test whether giving dexamethasone through a vein can improve pain control after total hip replacement surgery. Dexamethasone is commonly used to reduce nausea and may also help with pain, but it is not clear which…
- Trial name
- NCT07581470
- Testing
- Dexamethasone 4mg, Dexamethasone 8mg
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Poznan University of Medical Sciences
Arthroplasty, Replacement, Hip
Cementless New Alumina-zirconia Ceramic Bearing Total Hip Arthroplasty (THA) in Asian Patients
This study will evaluate a midterm clinical and radiologic outcome patients who undergo new alumina-zirconia composite ceramic bearing THA.
- Trial name
- NCT00935519
- Testing
- 4th generation ceramic bearing composite ceramic bearing
- Where
- South Korea
- Volunteers
- 310 people
- Sponsor
- Seoul National University Bundang Hospital
Nerve Block, Pain, Postoperative
Fascia Iliaca Compartment Block Versus Quadratus Lumborum Block in Total Hip Arthroplasty
Patients undergoing total hip arthroplasty are randomly assigned to two groups (fascia iliaca compartement block [FICB] group or quadratus lumborum block [QLB] group).
- Trial name
- NCT05228028
- Testing
- fascia iliaca compartement block, quadratus lumborum block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Total Hip Arthroplasty
Real-Time Instrument for Acetabular Shell Positioning
The proposed study is a double-blinded randomized controlled trial comparing Real-time instruments with solely standardized instruments for the placement of the acetabular cup prosthesis used in total hip arthroplasty.
- Trial name
- RTI (NCT02006251)
- Testing
- Real-time Instrumentation, Standard Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The Cleveland Clinic
Hip Osteoarthritis
Gait Analysis and Clinical Outcomes of Anterior and Lateral Approach Total Hip Arthroplasty.
The goal of this Prospective Randomized Study is to confirm presence or absence of differences in gait mechanics in direct anterior and lateral approaches for total hip arthroplasty.
- Trial name
- NCT06538519
- Testing
- total hip replacement using lateral approach, total hip replacement using anterior approach, gait analysis at 6wks, 3 months and 18 months
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Ain Shams University
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