Clinical trials: Hip Replacement, Total
Postoperative Quality of Recovery, Health-Related Quality-of-Life
The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study
Total hip arthroplasty (THA) is a highly effective and commonly performed procedure for end-stage osteoarthritis. Perioperative inflammation contributes to postoperative pain, fatigue, and delayed recovery.
- Conditions
- Postoperative Quality of Recovery, Health-Related Quality-of-Life, Quality of Life
- Trial name
- HIPSTER (NCT07378215)
- Testing
- Dexamethasone (IV)
- Where
- 2 sites in Belgium
- Volunteers
- 224 people
- Sponsor
- Ziekenhuis Oost-Limburg
Total Hip Replacement, Visual Biofeedback
Insole-based Visual Biofeedback for Weight-bearing in Total Hip Replacement
The study investigates the effects of visual biofeedback, based on a sensorized system for the dynamic evaluation of the plantar pressure versus rehabilitation with traditional verbal instructions of the physiotherapist, on…
- Conditions
- Total Hip Replacement, Visual Biofeedback, Weight Bearing
- Trial name
- NCT04268082
- Testing
- Visual biofeedback with the use of sensorized insoles, Standard rehabilitation based on physiotherapist's verbal instructions
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Hip Fractures
Hemiarthroplasty Versus Total Hip Replacement for Intracapsular Hip Fractures
In England each year over 9,000 people fracture their hip. Most of these are elderly females with the fracture occurring after a fall.
- Trial name
- NCT02998359
- Testing
- Hemiarthroplasty, Total hip arthroplasty
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust
Arthrosis
Prospective Study Deltamotion - DAA THA Study
1. Introduction Few gait analytical data are available concerning the Direct Anterior Approach (DAA) in total hip arthroplasty (THA). All the studies have focused on immediate post-operative recovery.
- Trial name
- NCT01474031
- Testing
- Biomechanics
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Osteoarthritis Arthritis, Rheumatoid Arthritis
G7 Acetabular System vs. Exceed ABT Acetabular System in THA
Evaluate the safety and effectiveness of patients who received G7 Acetabular system in conjunction with Ceramic on Ceramic articulation and Taperloc Complete Microplasty stem compared to patients who received the Exceed ABT…
- Trial name
- G7 (NCT02340390)
- Testing
- G7, Exceed ABT
- Where
- 3 sites in South Korea
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Arthritis
A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty
This is a prospective, randomized, controlled, single-center study to assess the effectiveness of Vitagel, a surgical hemostat, in primary unilateral total hip arthroplasty (THA).
- Trial name
- NCT01285024
- Testing
- Vitagel
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Arthroplasty Complications
Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty
Prospective randomized double blinded, placebo controlled study that will evaluate the effect of intra-operative ketamine administration on post-operative analgesic requirements and self-reported pain in patients undergoing total…
- Trial name
- NCT04437888
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Osteoarthritis, Post-traumatic Arthritis
A Randomised Single Centre Study to Compare the Long-term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement
The purpose of this study is to compare the performance and compare the wear characteristics of two polyethylene cup liners, Marathon™ and Enduron™, in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders, Avascular Necrosis
- Trial name
- NCT00208442
- Testing
- Marathon™, Enduron
- Where
- New Zealand
- Volunteers
- 122 people
- Sponsor
- DePuy International
Total Hip Arthroplasty (THA), Postoperative Pain Management
Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthroplasty
Background: In recent years, regional anesthesia has become more popular because it can reduce pain and the need for strong pain medications like morphine. For hip surgery, the PENG block is already known to be effective.
- Conditions
- Total Hip Arthroplasty (THA), Postoperative Pain Management, Peripheral Nerve Blocks, PENG Block
- Trial name
- NCT06964282
- Testing
- PENG Block, Iliopsoas nerve block
- Where
- Belgium
- Volunteers
- 118 people
- Sponsor
- University of Liege
Postoperative Anemia
A New Approach to a Personalized Patient Blood Management Program (pPBM) in Total Hip Arthroplasty (THA)
The study evaluates the patient related risk and predictive factors concerning perioperative homologous blood cell transfusion (erythrocyte concentrate ) in THA patients in one EndoCert max-certified orthopedic hospital in…
- Trial name
- NCT02519088
- Where
- Germany
- Volunteers
- 477 people
- Sponsor
- Krankenhaus der Barmherzigen Brüder Trier
Hip Osteoarthritis
Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis
Hip osteoarthritis is associated with joint pain, physical disability, decreased muscle strength and poor health status, and the most common cause for total hip arthroplasty.
- Trial name
- PROHIP (NCT04070027)
- Testing
- Total Hip Arthroplasty, Progressive Resistance Training
- Where
- 4 sites in Denmark
- Volunteers
- 109 people
- Sponsor
- Vejle Hospital
Total Hip Replacement, Total Knee Replacement
Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort Study
The goal of this prospective observational cohort study is to investigate dressing-related experiences and surgical site self-care in patients who are undergoing a total hip or knee replacement.
- Trial name
- DRESS-X (NCT07471243)
- Testing
- Wound Dressing Material
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Bournemouth University
Disorder of Hip Joint
Cerebral Oximetry and Anesthetic Technique
The purpose of the study is to compare the effects of spinal and general anesthesia on transcranial regional cerebral oxygen saturation in geriatric patients undergoing total hip arthroplasty.
- Trial name
- NCT03349658
- Testing
- general anesthesia, spinal anesthesia
- Volunteers
- 82 people
- Sponsor
- Antalya Training and Research Hospital
Wear of Articular Bearing Surface of Prosthetic Joint, Hip Arthropathy
Polyethylene Wear Particle Analysis of THA
Purpose of research The purpose of this study was to demonstrate that polyethylene (Vitamin E-containing polyethylene), a newly introduced biomaterial for tibial inserts in hip replacement surgery and widely used clinically, but…
- Trial name
- NCT06432543
- Testing
- polyethylene
- Where
- 2 sites in United States, Japan
- Volunteers
- 90 people
- Sponsor
- Osaka Metropolitan University
Arthoplasty, Nutrition
Effects of Preoperative Whey Protein and Exercise Support on Recovery After Total Hip Arthroplasty
Objective: The aim of this project is to evaluate the effects of preoperative whey protein supplementation and a physical exercise program on postoperative recovery outcomes in patients undergoing total hip arthroplasty (THA).
- Conditions
- Arthoplasty, Nutrition, Geriatric Assessment, Exercise Training
- Trial name
- THA (NCT07329010)
- Testing
- Preoperative Whey Protein and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- TC Erciyes University
Adverse Reactions to Metal Debris, Infection of Total Hip Joint Prosthesis
Imaging of Joint Replacement Complications by PET/CT
Total hip replacement is the well-established surgical method for treatment of hip osteoarthritis and related diseases. The outcome of the procedure is commonly satisfactory and most patients will not need any revision surgery.
- Conditions
- Adverse Reactions to Metal Debris, Infection of Total Hip Joint Prosthesis, Mechanical Loosening of Prosthetic Joint
- Trial name
- Propeli (NCT01970228)
- Testing
- 68Ga-citrate and 18F-FDG PET/CT imaging
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Turku University Hospital
Total Hip Replacement, Pain
Long Term Follow-Up After Patients Underwent Total Hip Replacement
The investigators want to contact patients that underwent total hip replacement for the past ten years. The investigators will ask them about their daily living, functioning and quality of life.
- Trial name
- NCT01687322
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Hadassah Medical Organization
Total Hip Arthroplasty
Effectiveness of Fast-track Clinical Pathway on Minimally-invasive Total Hip Arthroplasty Surgery in NTUH
The objective of this study was to evaluate the effects of an enhanced recovery after surgery (ERAS) pathway incorporated with pre-operative physical therapy and education on immediate and short-term outcomes of…
- Trial name
- NCT04145921
- Testing
- ERAS for MIS-THA, conventional MIS-THA
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital
Arthritis
Sexual Function Questionnaire Total Hip Replacement
Non-commercial trial 2 Centres involved: University Hospital Southampton and Spire Southampton Expected number of eligible participants available per year: 100, (95% expected to agree to participation) The study will recruit…
- Trial name
- NCT02290652
- Testing
- Prospective - Factors affecting sexual function pre-THR, Retrospective- Factors affecting sexual function post-THR
- Where
- 2 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Post Operative Pain, Total Hip Arthroplasty
Methadone in THA for Post-op Pain and Opioid Reduction
This randomized, double-blind controlled trial investigates whether intraoperative intravenous methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing…
- Trial name
- NCT07227064
- Testing
- Methadone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Medical University of South Carolina
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