Clinical trials: Hip Replacement, Total
Same-day Discharge, Length of Stay
Preoperative Oral Hydration in the Ambulatory Arthroplasty Population
The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint…
- Trial name
- NCT05520593
- Testing
- Complex Carbohydrate Drink
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Regional Anaesthesia
QLESP Block Versus Periarticular Infiltration for Postoperative Analgesia in Hip Surgery
Local and/or regional analgesia techniques are critical components of an optimal multimodal analgesia technique, as they have been shown to improve pain relief as well as reduce opioid requirements.
- Trial name
- NCT06688136
- Testing
- ropivacaine
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Huazhong University of Science and Technology
Total Hip Replacement Surgery
Assessing the Perioperative Outcomes of Minimally Invasive Posterior Approach Versus Direct Anterior Approach Total Hip Arthroplasty.
The aim of the present study is to compare the early post-operative outcomes of minimally invasive posterolateral approach (Mis-PLA) Vs.
- Trial name
- PTACONF (NCT06659198)
- Testing
- total hip replacement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Arthropathy of Hip
A Dose-response Study of Tranexamic Acid in Total Hip Arthroplasty
A single preoperative dose of tranexamic acid (TXA) reduces blood loss and red blood cell transfusion in primary hip arthroplasty. Numerous regimens have been tested, ranging from 10mg/kg up to 3g.
- Trial name
- PRADO (NCT03822793)
- Testing
- Group 1: perfusion of 300 mg Exacyl, Group 2: perfusion of 500 mg Exacyl, Group 3: perfusion of 1000 mg Exacyl
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE)
Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)
Evaluation of the safety and effectiveness of ActiveCare+ CECT device +/- baby dose aspirin (81 mg QD) for lowering the potential risk for bleeding and of DVT during and after THA surgery in comparison with LMWH.
- Conditions
- Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE), Bleeding
- Trial name
- SAFE (NCT00358735)
- Testing
- ActiveCare CECT device, Enoxaparin
- Where
- 9 sites in United States
- Volunteers
- 411 people
- Sponsor
- Medical Compression Systems
Osteoarthritis
Time of Intravenous Acetaminophen Administration
The purpose of the study is to examine the effects of timing of administration of intravenous (IV) acetaminophen and how timing relates to analgesic efficacy as measured by postoperative pain scores.
- Trial name
- TIAA (NCT01699815)
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Duke University
Knee Phenotype Changes After THA, Coronal Plane Alignment of the Knee
Change of Knee Phenotype After Total Hip Arthroplasty
this study evaluates changes in knee phenotype after total hip arthroplasty using radiographic assessment of coronal alignment in a prospective cohort of patients
- Trial name
- THA-KP (NCT07597538)
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nader Ahmed Sayed Abdelhamed
Joint Disease
Evaluation of Bone Mineral Density Changes After Total Hip Replacement: A Two-Year Clinical and DXA Analysis
Sponsor is conducting this post-market study to evaluate the clinical outcome and femoral bone mineral density (BMD) changes associated with the PROFEMUR® PRESERVE hip stem when used as indicated for primary total hip…
- Trial name
- NCT02865447
- Testing
- total hip arthroplasty implant
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- MicroPort Orthopedics Inc.
Short Stem Prosthesis, Optimys Femoral Stem
Optimys Femoral Stem for Total Hip Replacement
This retrospective observational study analyses the surgical performance, clinical and radiologic outcome as well as the rate of infections with a main focus on revision surgeries after primary implantation of the Optimys short…
- Trial name
- Optihip (NCT03951948)
- Testing
- retrospective analysis of surgical performance, clinical and radiologic outcome
- Where
- Switzerland
- Volunteers
- 453 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis, Hip
A Comparative Study of Stem and Cup Fixation and Polyethylene Wear
A randomized controlled study comparing two types of cementless femoral stems (LCU and Corail) and two types of acetabular components (DeltaTT and Pinnacle Duofix) in primary total hip arthroplasty.
- Trial name
- NCT04064723
- Testing
- Randomization between prosthetic components
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Arthritis
Serologic Characterization of Bone-healing
Investigation of serologic bone markers in patients undergoing hip arthroplasty
- Trial name
- NCT00377884
- Where
- 2 sites in Denmark
- Sponsor
- Northern Orthopaedic Division, Denmark
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up
The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery.
- Trial name
- NCT01103752
- Testing
- no intervention, descriptive study
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Lene Krenk
Venous Thromboembolism (VTE), Total Joint Arthroplasty
Efficacy of Aspirin in Preventing Venous Thromboembolism
Efficacy of aspirin and enoxaparin in preventing venous tromboembolism was compared after total knee or hip arthroplasty.
- Conditions
- Venous Thromboembolism (VTE), Total Joint Arthroplasty, Total Hip Arthroplasty (THA)
- Trial name
- NCT06635317
- Testing
- Aspirin, enoxaparin
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Total Hip Arthroplasty, Hip Arthrosis
Tissue Sparing Surgery in Total Hip Arthroplasty
Rationale of the study is to evaluate through a prospective randomized controlled study if a modified direct superior posterolateral approach (sperimental approach) to the hip articulation which entirely spares i.e.
- Trial name
- NCT04358250
- Testing
- Direct Superior Approach, posterolateral approach
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Ossification, Heterotopic
Prevention of Heterotopic Ossification With Arcoxia After Total Hip Replacement
The purpose of the study is to determine whether Arcoxia is effective in preventing heterotopic ossification after total hip arthroplasty.
- Trial name
- Arcoxia (NCT01022190)
- Testing
- Etoricoxib (Arcoxia)
- Where
- Netherlands
- Volunteers
- 42 people
- Sponsor
- Radboud University Medical Center
Total Hip Arthroplasty (THA)
Comparison Between Automated and Manual Component Impaction in Total Hip Arthroplasty
This study will investigate and evaluate the ergonomic impaction and the operational efficiency of the KINCISE™ impaction system in comparison with the manual impaction of a handheld traditional mallet in total hip arthroplasty…
- Trial name
- KINCISE (NCT05480813)
- Testing
- Automated KINCISE™ impaction system versus handheld traditional mallet, Efficiency and ergonomics analysis and physical assessments
- Where
- Belgium
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- DEO NV
Osteoarthritis, Avascular Necrosis
Metal Ions in Ceramic on Metal Total Hip Arthroplasty
The investigators aim to measure the blood levels of certain metals in a group of patients all of whom have had a ceramic on metal total hip replacement.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Developmental Dysplasia of the Hip
- Trial name
- COM (NCT01437124)
- Where
- United Kingdom
- Volunteers
- 83 people
- Sponsor
- Hussain Kazi
Hip Osteoarthritis, Arthropathy of Hip
Total Hip Arthroplasty: Fast Track Protocol is the Future?
Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-H (NCT03875976)
- Testing
- Fast Track Protocol, Standard Care Protocol
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Postoperative Pain
Effect of Quadro-Iliac Plane Block on Recovery After Total Hip Arthroplasty
Total hip arthroplasty is a widely performed surgical procedure in the elderly population, aiming to relieve hip joint pain and restore function.
- Trial name
- NCT06870071
- Testing
- Control group, Quadro iliac plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Konya City Hospital
Neuromuscular Blockade, Innate Inflammatory Response
Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function
Monocenter randomized controlled trial to compare the effect of deep neuromuscular blockade (NMB) versus moderate NMB during total hip replacement surgery on postoperative quality of recovery and innate immune function.
- Conditions
- Neuromuscular Blockade, Innate Inflammatory Response, Quality of Life, Postoperative Complications
- Trial name
- HIPPO (NCT05562999)
- Testing
- Rocuronium Bromide
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
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