Clinical trials: Hip Replacement, Total
Postoperative Pain Intensity, Rescue Pain Requirements
Pain Management Following Total Hip Arthroplasty
Total hip arthroplasty (THA) is a common and standardized procedure. Postoperative mortality after hip joint replacement is low but some complications remain, including chronic post-surgical pain (1), hip dislocation (2)…
- Trial name
- FEMORALIA (NCT02568995)
- Testing
- ropivacaine + ketorolac + adrenaline
- Where
- 3 sites in Sweden
- Volunteers
- 55 people
- Sponsor
- Örebro University, Sweden
Infection
One-Stage Exchange for Chronically Infected Total Hip Arthroplasty
The primary goal of the study is to evaluate the success rate of routine one-stage exchange for treatment of chronically infected total hip arthroplasty performed at the investigators institution, and to compare it to the current…
- Trial name
- NCT02825381
- Where
- France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Strasbourg, France
Coxarthrosis
Measurement of Early Bone Loss Around a Total Hip Arthroplasty
Research with DXA has shown the pattern of bone remodelling around an implant. The baseline and reference value for such calculations is the first measurement after the operation.
- Trial name
- DXACorail (NCT01046019)
- Volunteers
- 23 people
- Sponsor
- Ullevaal University Hospital
Postoperative Anemia, Arthroplasty, Replacement, Hip
Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia
To assess the safety, tolerability, efficacy, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of orally administered SSS17 capsules in patients with postoperative anemia following elective total hip or knee…
- Conditions
- Postoperative Anemia, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT07007936
- Testing
- SSS17 Capsule (6 Dose Levels)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Post Operative Blood Loss
Role of Topical Tranexamic Acid in Total Hip Arthroplasty
Total hip arthroplasty (THA) is a procedure associated with perioperative blood loss, requiring blood transfusions in some patients.
- Trial name
- TXA (NCT01866943)
- Testing
- Tranexamic Acid, Normal Saline Solution
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Osteoarthritis, Hip
Preheating of Femur Component in Hybrid Total Hip Arthroplasty
Background Recently published studies confirm that preheating of femoral component enhances shear strength of implant-cement interface.
- Trial name
- NCT00319085
- Testing
- Total hip replacement (Preheating of femur stem)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Total Hip Arthroplasty
A Post Market Surveillance Study About the MONOCER Cup
Over the years, the use of large diameter femoral heads has become increasingly common in orthopaedics due to the decreased risk of dislocation due to increased jumping distance and range of motion.
- Trial name
- NCT05785364
- Testing
- Mpact 3D metal MONOCER cup
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Medacta International SA
Revision Total Hip Arthroplasty, Primary Total Hip Arthroplasty
Retrospective Observational Cohort Study of SYMBOL CUP DM 2
This is a single-center retrospective observational cohort study of consecutively operated patients who underwent total hip arthroplasty (THA) with a SYMBOL CUP DMR HA or a SYMBOL CUP DM CEM hemispherical dual mobility acetabular…
- Trial name
- SYMCOR-2 (NCT04209426)
- Testing
- THA with SYMBOL CUP DMR HA, THA with SYMBOL CUP DM CEM
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Dedienne Sante S.A.S.
Total Hip Arthroplasty, Wear
Age Dependency of Biological Reaction on Wear Particles
Wear is the main reason for revision operations after joint arthroplasty. While the survival of modern implants is often longer than the expected life span in old patients, young patients (<60 years) have to expect at least one…
- Trial name
- NCT03164733
- Testing
- incubation
- Volunteers
- 80 people
- Sponsor
- University of Jena
Osteoarthritis
Clinical Study on BiHapro Total Hip System With Different Surface Coatings
This post market study intends to evaluate the safety and the performance of BiHapro Total Hip System with two types of coatings.
- Trial name
- NCT00755001
- Testing
- BiHapro hip stem with PPS Ti+Plasma HA, BiHapro hip stem with PPS Ti+BoneMaster HA
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Thromboembolism
Pradaxa (Dabigatran Etexilate 220 mg/q.d. in the General Population After Hip or Knee Replacement Surgery
An observational cohort study on safety and efficacy of the 220 mg dose Pradaxa to generate additional data in predefined sub populations of patients at increased risk of bleeding or VTE
- Trial name
- NCT00846807
- Where
- 112 sites in Austria, France and 7 more
- Volunteers
- 5,476 people
- Sponsor
- Boehringer Ingelheim
Arthroplasty, Replacement
Comparison of Metal on Metal Total Hip Arthroplasty and Metal on Metal Total Hip Resurfacing.
The goal of this double-blind prospective randomized study is to compare subjective outcome measures and gait parameters between conventional THA using large diameter femoral heads and total hip resurfacing
- Conditions
- Arthroplasty, Replacement, Hip
- Trial name
- NCT04516239
- Testing
- THA, HR
- Volunteers
- 48 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Total Hip Replacement
Effectiveness of Patient-Controlled Intravenous Analgesia (PCIA) With Fentanyl
To enhance post-operative pain management, patient-controlled intravenous analgesia (PCIA) has been employed. The fentanyl background PCIA therapy was created to solve the limitations of IV-based PCIA, such as programming errors…
- Trial name
- NCT05429567
- Testing
- Fentanyl
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Egymedicalpedia
Arthroplasty, Hip, Replacement
Study to Evaluate the Performance and Safety of ATF Implants and Lapé Médical Devices Implanted During Hip Arthroplasty
Observational and prospective multicenter study to evaluate the long-term (10 years) performance and safety (10 years) of ATF Implants and Lapé Médical devices implanted during total hip arthroplasty or hemiarthroplasty.
- Trial name
- NCT05044767
- Testing
- total hip arthroplasty
- Where
- 13 sites in France
- Volunteers
- 4,500 people
- Sponsor
- ATF Implants
Arthrosis
Prospective Study Deltamotion - DAA THA Study
1. Introduction Few gait analytical data are available concerning the Direct Anterior Approach (DAA) in total hip arthroplasty (THA). All the studies have focused on immediate post-operative recovery.
- Trial name
- NCT01474031
- Testing
- Biomechanics
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Total Hip Arthroplasty (THA)
Alexis O-Ring and Charnley Retrievers and Its Effect on Contamination on Total Hip Arthroplasty
Randomized, prospective, single-blind clinical trial comparing two static wound retractors - the Charnley retractor and the Alexis O-Ring retractor - in primary total hip arthroplasty (THA).
- Trial name
- NCT07621250
- Testing
- Alexis O-Ring Wound Retractor, Charnley Retractor
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Hospital del Mar
Erythema, Drainage
A Comparison of INSORB Staples With Metal Staples in Total Hip Replacement
The purpose of this study is to compare the use of INSORB absorbable staples with metal staples on surgical incision healing after total hip replacement.
- Conditions
- Erythema, Drainage, Bruising, Pain
- Trial name
- NCT00940446
- Testing
- Insorb staples, metal staples (Ethicon metal stapler)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Research Foundation
Osteoarthritis, Hip, Arthroplasty Complications
Incidence of 30 Day Return to Hospital Following Same Day Discharge Total Hip Arthroplasty
Amongst patients who are discharged home from hospital on the same day as their elective Primary Total Hip Arthroplasty, the Investigators seek to quantify the incidence of return to hospital within 30 days of surgery for…
- Conditions
- Osteoarthritis, Hip, Arthroplasty Complications, Complication of Surgical Procedure, Perioperative Complication
- Trial name
- NCT04120324
- Testing
- Eligible for Same Day Discharge, Primary Single Joint Total Hip Arthroplasty, Discharge Same Day
- Where
- Canada
- Volunteers
- 109 people
- Sponsor
- University of British Columbia
Arthroplasty, Mineral Density
Effect of Local Pamidronate in Preventing Bone Loss After Total Hip Arthroplasty
The aims of the study are to determine whether pamidronate applied locally causes diminished periprosthetic bone loss and decreased rate of bone turnover compared to patients receiving placebo after cemented total hip…
- Trial name
- NCT00548288
- Testing
- pamidronate
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- General and Teaching Hospital Celje
Hip Arthritis, Total Hip Arthroplasty
The Impact of Two Different Physical Therapy Programs in the Rehabilitation of Patients Undergoing Anterior Approach Hip Replacement Surgery
This study will look to determine two different types of physical therapy regimens in patients who undergo anterior total hip replacement. We will compare the results of two groups.
- Trial name
- NCT04492462
- Testing
- Formal Physical Therapy, Self-directed Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
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