Clinical trials: Hip Replacement Arthroplasty
Analgesics, Opioid, Anesthesia, Spinal
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Pain management after total hip replacement is one of the most important aspects of postoperative care for patients and clinicians alike.
- Conditions
- Analgesics, Opioid, Anesthesia, Spinal, Total Hip Replacement, Adverse Anesthesia Outcome
- Trial name
- NCT06878014
- Testing
- Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone
- Where
- 3 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Anesthesia, Local, Analgesia
The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replacement.
Total hip replacement surgery is one of the most common orthopedic interventions. Proper anaesthesia and adequate analgesia is one of the key interests of attending anaesthetist.
- Conditions
- Anesthesia, Local, Analgesia, Arthropathy of Hip
- Trial name
- NCT04690647
- Testing
- Opioid and non opioid postoperative analgesia., Fascia iliaca compartment block, Dexamethasone
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Saint Lucas Hospital, Poland
Venous Thromboembolism, Bleeding
Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)
Several human genes affect how medications are metabolized by the body. It is believed that knowledge of variations of these genes can help health care providers better manage an anticoagulation medicine called warfarin…
- Trial name
- NCT00634907
- Testing
- Pharmacogenetic-based warfarin dosing, Usual care warfarin dosing
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Gwen McMillin
Hip Replacement Arthroplasty
Determination of Metal Ion Serum Levels and Cytokines in Total Hip Replacement
The goal of the study is the analysis of metal ion serum concentrations and of the cytokine production in the blood of patients with a conventional cementless total hip replacement.
- Trial name
- NCT01394744
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Testing Implementation of Total Joint Replacement Rehabilitation Quality Indicator Toolkits
The goal of this feasibility study is to test the procedures for implementing quality indicator toolkits for hip and knee replacement rehabilitation in clinical settings.
- Trial name
- NCT06208553
- Testing
- QI toolkit implementation
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- University of British Columbia
Spinal Anesthesia
Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
In the current healthcare system, a short length of stay is paramount, for medical, functional, and financial reasons. Most patients undergoing hip and knee replacement at Hôpital Montfort institution receive spinal anesthetic…
- Trial name
- NCT04280939
- Testing
- spinal anesthesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hopital Montfort
Arthroplasty, Replacement, Hip
Secur-Fit Advanced Outcomes Study
The goal of this study is to evaluate the Secur-Fit Advanced Hip Stem in primary total hip replacement surgery.
- Trial name
- NCT01917929
- Testing
- Secur-Fit Advanced Hip Stem
- Where
- 8 sites in United States
- Volunteers
- 326 people
- Sponsor
- Stryker Orthopaedics
POSTOPERATIVE ANALGESIA
PENG Block and Lateral Femoral Cutaneous Nerve Block For Hip Replacement Surgery
Background: this study aimed to describe the pain relief outcomes after hip replacement surgery by continuous Pericapsular Nerve Group Block (PENG Block) in combination with lateral femoral cutaneous nerve (LFCN) block under the…
- Trial name
- NCT06040879
- Testing
- PERICAPSULAR NERVE GROUP BLOCK COMBINED WITH LATERAL FEMORAL CUTANEOUS NERVE BLOCK
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Hanoi Medical University
Osteoarthritis
Comparison of Two Minimally Invasive Surgical Techniques for Hip Replacement
Comparison of the clinical effectiveness and cost-effectiveness of the MIS anterolateral approach (MIS Watson Jones, G3) versus anterolateral mini or posterolateral mini approaches in primary total hip arthroplasty
- Trial name
- NCT00175461
- Testing
- hip surgery
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- University of British Columbia
Total Hip Arthroplasty, Total Hip Replacement
Total Hip Replacement With Ceramic on Ceramic Bearing- Clinical Follow-up Study
The pain and severe wear of hip joints caused by osteoarthritis, rheumatoid arthritis, avascular necrosis and trauma can be subjected to total hip replacement (THR).
- Trial name
- NCT04256291
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Hip Replacement, Total
Tranexamic Acid Versus Placebo for the Reduction of Blood Loss in Total Hip Replacement Surgery
The bleeding caused by hip replacement surgery (CRT) is an important source of demand for blood in the hospital. Tranexamic acid (TXA) is a drug that has proved useful in reducing bleeding associated with other surgeries and CRT…
- Trial name
- TXA-CRT (NCT01199627)
- Testing
- A, B, C
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Basque Health Service
Pain, Osteoarthritis, Knee
Brief Nurse-led Mindfulness Based Intervention
This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The feasibility, acceptability, and clinical effects of the nurse-led, very brief, preoperative mindfulness based intervention for hip and knee…
- Conditions
- Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04800354
- Testing
- Nurse-led Mindfulness Based Intervention, Nurse-led Pain Psychoeducation
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- University of Utah
Non-inflammatory Degenerative Joint Disease
Metal Ion Release From an FDA-Approved Metal-on-Metal Total Hip Replacement Implant
This is a multi-center, randomized study to compare blood and urine cobalt, chromium, and titanium ion levels of a metal-on-metal articular bearing coupled with two different head sizes to that of a conventional…
- Trial name
- NCT00962351
- Testing
- Total Hip Replacement
- Where
- 2 sites in United States, Canada
- Volunteers
- 120 people
- Sponsor
- Anderson Orthopaedic Research Institute
Rehabilitation, Telerehabilitation
Does Rehabilitation After Total Hip Or Knee Arthroplasty Work (DRAW2)
Overall frame: The overall or "parent" DRAW-project is a large-scale project run in Denmark that aims to provide substantial level 1A evidence-data related to the question: Does rehabilitation after total hip and knee…
- Conditions
- Rehabilitation, Telerehabilitation, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- DRAW2 (NCT04960241)
- Testing
- Homebased telerehabilitation, Homebased rehabilitation, No physical rehabilitation
- Where
- Denmark
- Volunteers
- 169 people
- Sponsor
- Troels Mark Christensen
Anesthesia, Post Operative Pain
Volume Effect in Peng Block for Total Hip Replacement
This study is to investigate whether a different volume of ropivacaine, with the same prescribed dosage based on body weight, can affect block efficacy, duration and side effects in the first 24 hours postoperatively.
- Trial name
- volupeng (NCT06427551)
- Testing
- Ropivacaine
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Anesthesia, Orthopedic Surgery
Does Midazolam Cause Effective Anterograde Amnesia in Orthopedic Surgeries?
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia.
- Trial name
- NCT04232150
- Testing
- single-dose midazolam for sedation under spinal anesthesia., Double-dose midazolam for sedation under spinal anesthesia., spinal anesthesia with no sedation.
- Where
- Jordan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Arthropathy of Knee, Arthropathy of Hip
Nirvana Super Pro Supplementation in Orthopedic Surgery Patients
The purpose of this study is to investigate orthopedic patients undergoing either a total hip replacement (THR) or total knee arthroplasty (TKR) using two dietary supplements, PREPARE and RECOVER, and their recovery times…
- Trial name
- NCT06203691
- Testing
- Supplementation with Nirvana Super Pro Liquid Supplements, Non-Supplementation Group
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nirvana Water Sciences Corp
Osteoarthritis, Hip
Is Drainage Necessary After Total Hip Replacement?
The goal of this study was to compare early results of Total Hip Replacement (THR) in 2 groups of patients: with and without closed suction drainage (CSD). Patients were followed for 3 months post operatively.
- Trial name
- NCT02562586
- Testing
- Closed Suction Drainage System
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- University of Sao Paulo
Total Hip Replacement, Wound Complication
Hip DAA Closure Techniques
This study aims to analyze the difference in rates of wound complications using two different closure techniques in Direct anterior approach for primary total hip replacement.
- Trial name
- NCT06006572
- Testing
- wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive, wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics