Clinical trials: Hip Replacement Arthroplasty
Total Hip Replacement, Pericapsular Nerve Group Bloc
Effect of Pericapsular Nerve Group Block on Postoperative Cognitive Function
The aim of this study was to examine the effect of pericapsular nerve group (PENG) block, which is frequently applied for postoperative analgesia in total hip replacement surgeries performed under spinal anesthesia, on…
- Conditions
- Total Hip Replacement, Pericapsular Nerve Group Bloc, Postoperative Cognitive Dysfunction
- Trial name
- NCT06736405
- Testing
- Pericapsular nerve group block, No Pericapsular nerve group block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis
Blood Management in Orthopedic Surgery
Aim: to investigate whether the use of several transfusion alternatives (erythropoietin, the cell-saver or postoperative drainage and reinfusion systems) in patients undergoing elective total knee or hip replacement surgery can…
- Trial name
- TOMaat (NCT00998088)
- Testing
- erythropoietin and cell saver, erythropoietin, OrthoPAT
- Where
- 4 sites in Netherlands
- Volunteers
- 2,598 people
- Sponsor
- Sanquin Research & Blood Bank Divisions
Anesthesia, Orthopedic Surgery
Does Midazolam Cause Effective Anterograde Amnesia in Orthopedic Surgeries?
Spinal anesthesia is one of the commonest choices of anesthesia for infraumbilical surgeries.The use of sedation has markedly increased patients' comfort and acceptance towards spinal anesthesia.
- Trial name
- NCT04232150
- Testing
- single-dose midazolam for sedation under spinal anesthesia., Double-dose midazolam for sedation under spinal anesthesia., spinal anesthesia with no sedation.
- Where
- Jordan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Hip Replacement, Total
Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application Total Hip Arthroplasty
Total hip arthroplasty (THA) is an excellent surgical procedure for patients with end-stage hip diseases. However, THA is associated with considerable blood loss and increasing needs for allogenic blood transfusion.
- Trial name
- NCT03623789
- Testing
- intravenous application of tranexamic acid, Floseal hemostatic matrix, Normal saline
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hip Osteoarthritis
Prospective Randomised Study of a New an Uncemented Stem.
Patients will be randomised to either operation with a Corail stem or a SP-CL stem. The groups are examined with RSA, conventional x-rays, PROM-data and DXA. First evaluation will be done at two years.
- Trial name
- NCT04599582
- Testing
- Hip Arthroplasty
- Volunteers
- 80 people
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis, Hip
Change of Cognitive Performance Through Hip Replacement
The purpose of this study is to investigate the effectiveness of a hip arthroplasty for chronic pain, caused by a unilateral primary Coxartrhrose, regarding the cognitive performance.
- Trial name
- KogniTEP (NCT02997891)
- Testing
- everyday activity, cognitive performance
- Where
- 2 sites in Germany
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Total Hip Replacement Surgery
Analgesia in Total Hip Arthroplasty by Quadratus Lumborum Block
Patients are painful after total hip arthroplasty. These patients have significant co-morbidities. Analgesics cause significant side effects in this population.
- Trial name
- ATHAQLuB (NCT03666260)
- Testing
- Quadratus Lumborum Block, femoral block
- Where
- France
- Volunteers
- 179 people
- Sponsor
- CHU de Reims
Infection, Hip Joint Replacement
Cementless One-stage Revision of the Chronic Infected Hip Arthroplasty
The investigators hypothesise that cementless one-stage exchange revision surgery can be performed in patients with chronically infected hip replacement with substantial benefits for the patients, in terms of fast rehabilitation…
- Trial name
- CORIHA (NCT01015365)
- Testing
- Cementless one-stage surgical revision
- Where
- 8 sites in Denmark
- Volunteers
- 56 people
- Sponsor
- University of Aarhus
Bone Fracture
HealthEast Community Hip and Knee Replacement Registry
HealthEast Care System began the first community-based joint replacement registry (HJRR) in the U.S. in 1991, and now has more than 30,000 total joints registered.
- Trial name
- HEJR (NCT02692092)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- HealthEast Care System
Ankle Injuries, Femoral Neck Fractures
Clinical Use of Andante SmartStep System in Gait Rehabilitation
The purpose of this study is to evaluate the effectiveness of the biofeedback gait training device in improving load bearing over an operated limb, during post-operative gait training therapy.
- Trial name
- NCT00268658
- Testing
- SmartStep(tm) biofeedback device
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Does Rehabilitation After Total Hip and Knee Arthroplasty Work
Background: Total hip- and knee arthroplasty (THA and TKA) is recommended for relieving pain and restoring function for end-stage osteoarthritis, when non-surgical treatment has failed to relieve symptoms.
- Conditions
- Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Telerehabilitation, Rehabilitation
- Trial name
- DRAW1 (NCT03750448)
- Testing
- Telerehabilitation, No intervention, Unsupervised rehabilitation
- Where
- 3 sites in Denmark
- Volunteers
- 168 people
- Sponsor
- Bornholms Regionskommune
Hip Replacement
Patient Outcomes Using HIP7 Software as Compared to Conventional THA
The study is designed to demonstrate how Hip7 software can lead to improved patient outcomes compared to conventional procedures with standard instrumentation for total hip arthroplasties (THA) surgery.
- Trial name
- NCT04989998
- Testing
- Hip7 Software on Kick/ CORI platforms, Conventional surgical procedures
- Sponsor
- Smith & Nephew Orthopaedics AG
Total Hip Replacement, Ultrasound Guided Supra-inguinal Fascia Iliaca Block
The Efficacy of Pain Control After Total Hip Replacement Between Ultrasound Guided Supra-inguinal Fascia Iliaca Block and Intrathecal Morphine
Total hip replacement is one of major orthopedic surgery which result in severe postoperative pain especially at first 24 hours.
- Conditions
- Total Hip Replacement, Ultrasound Guided Supra-inguinal Fascia Iliaca Block, Intrathecal Morphine, Postoperative Pain
- Trial name
- NCT04104204
- Testing
- Intrathecal morphine, Ultrasound guided supra-inguinal fascia iliaca block
- Where
- Thailand
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Osteoarthritis, Pain
Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as Monotherapy compared with placebo in participants with signs and symptoms of osteoarthritis of the hip or knee that are not…
- Trial name
- NCT02336698
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg
- Where
- 32 sites in United States, Poland and 2 more
- Volunteers
- 18 people
- Sponsor
- Janssen Research & Development, LLC
Total Hip Replacement
Twenty-Four Seven Functional Status in Total Hip Replacement
The goal of this observational study is to define digital remote monitoring measures for functional status (activities of daily living) in patients receiving total hip replacement.
- Trial name
- LEARNT (NCT06209216)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Koneksa Health
Non-inflammatory Degenerative Joint Disease
Multi-Center Comparative Trial of the ASR™-XL Acetabular Cup System vs. the Pinnacle™ Metal- on- Metal Total Hip System
The primary objective of this investigation is to evaluate the clinical and radiographic outcomes of the ASR™-XL Acetabular Cup System compared to the Pinnacle™ Acetabular Cup with a 28mm or 36mm ULTAMET™ metal insert.
- Trial name
- ASR (NCT00561600)
- Testing
- ASR™-XL Modular Acetabular Cup System, Pinnacle™ acetabular shell
- Where
- 8 sites in United States
- Volunteers
- 265 people
- Sponsor
- DePuy Orthopaedics
Arthroplasty, Hip Replacement, Infection, Postoperative Wound
Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery
This study will assess the efficacy of two of the most commonly used surgical skin-preparation solutions: Chloraprep (chlorhexidine-alcohol) and Duraprep (iodine-alcohol) at eliminating bacteria from the hip site by evaluating…
- Trial name
- NCT03393819
- Testing
- DuraPrep, ChloraPrep
- Volunteers
- 105 people
- Sponsor
- Lakehead University
Total Hip Replacement
Study of the Wear of a Highly Cross-linked Polyethylene Acetabular Doped With Vitamin E and Coated With Titanium in Total Hip Replacement
The total hip replacement, with over 120,000 cases per year in France, provides short term, excellent functional results and a significant improvement in quality of life, in almost all cases.
- Trial name
- POLYTITAN (NCT02524587)
- Testing
- standard polyethylene acetabular irradiated at 3 Mrad, radio stereometric analysis (RSA) of the acetabular, acetabular polyethylene vitamys®
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Caen
Venous Thromboembolism
Xarelto Regulatory Post-Marketing Surveillance
This study is to identify the following problems and questions with respect to the safety and effectiveness of Xarelto in comparison with other pharmacologic agents in the prophylaxis of venous thromboembolism (VTE) in a large…
- Trial name
- NCT01029743
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Pharmacologic agents (e.g. LMWH/VKA/Fondaparinux/Aspirin and etc.)
- Where
- South Korea
- Volunteers
- 3,388 people
- Sponsor
- Bayer
Osteoarthritis (OA), Osteoarthritis (OA) of the Hip
Evaluation of Choose to Move Replacement Ready (CTM-RR)
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
- Trial name
- CTM-RR (NCT07696650)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia