Clinical trials: Hip Replacement Arthroplasty
Pain, Postoperative
Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management
The purpose of this study is to compare two medications currently injected intra-operatively to help decrease pain after surgery in patients undergoing a primary total hip replacement (THR).
- Trial name
- NCT03001453
- Testing
- Liposomal Bupivacaine, 0.25% Bupivacaine with epinephrine, Saline
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- American Hip Institute
Hip Disease
ACE Acetabular Cup UK Multi-centre PMCF Study
A total hip replacement is one of the most successful and cost-effective surgical procedures in orthopaedics, and involves replacing both the hip ball and socket.
- Trial name
- NCT04123431
- Testing
- Total Hip Replacement
- Where
- United Kingdom
- Volunteers
- 225 people
- Sponsor
- JRI Orthopaedics
Rheumatoid Arthritis, Osteoarthritis
A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the Pinnacle™ Cup with a ceramic-on-ceramic bearing combination in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872222
- Testing
- Pinnacle™ Acetabular System
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- DePuy International
Hip Osteoarthritis, Knee Osteoarthritis
Comparative Effectiveness of Decision Support Strategies for Joint Replacement Surgery
This study is a 2X2 factorial randomized trial that will the examine the comparative effectiveness of two patient decision aids for hip and knee osteoarthritis (OA) as well as the impact of a surgeon-focused intervention.
- Trial name
- NCT02729831
- Testing
- Interactive decision aid, Video decision aid, Provider Report
- Where
- 3 sites in United States
- Volunteers
- 1,220 people
- Sponsor
- Massachusetts General Hospital
Regional Anesthesia, Postoperative Pain
US-guided Pericapsular Nerve Group (PENG) Block in Different Volumes on Postoperative Pain in Hip Replacement Surgeries
Postoperative pain management has an important place in anesthesia practices. In order to ensure patient comfort after the surgery, to start postoperative rehabilitation early, and to prevent the process from causing mood…
- Conditions
- Regional Anesthesia, Postoperative Pain, Hip Surgery
- Trial name
- NCT06166602
- Testing
- PENG block with 0.25% bupivacaine.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Osteoarthritis, Hip
Metal-metal Articulations Versus Standard 28 mm Cementless Total Hip Arthroplasty
Younger hip patients often need revision of their hip replacement due to wear and loosening. Newer concepts (resurfacing and large head total hip replacement) with articulation surfaces in metal may reduce the wear, increase the…
- Trial name
- NCT01113762
- Testing
- articular surface replacement ASR, DePuy, ReCap/Magnum modular head, Biomet, Bimetric stem, mallory/head cup, 28 mm ceramic head, Biomet
- Where
- 2 sites in Denmark
- Volunteers
- 71 people
- Sponsor
- University of Southern Denmark
Arthropathy of Hip
A Combined Nerve Block in Elderly Patients Subjected to Total Hip Replacement
The purpose of this study is to validate the hypothesis that a combined nerve block produces better outcomes including intraoperative stress, hemorrheological indexes, postoperative immune function, and incidence of postoperative…
- Trial name
- NCT02884388
- Testing
- combined nerve block, general anesthesia
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qinghai University
Non-inflammatory Joint Diseases
Metal on Metal Versus Ceramic on Metal Hip Replacement
The purpose of this study is to compare the performance of artificial hips with metal heads and metal sockets to artificial hips with ceramic heads articulating with metal socket components.
- Trial name
- NCT00208494
- Testing
- Total Hip Replacement
- Where
- 9 sites in United States, Canada
- Volunteers
- 392 people
- Sponsor
- DePuy Orthopaedics
Hip Osteoarthritis, Hip Arthropathy
The Pericapsular Nerve Block in Total Hip Arthroplasty
In order to continue progressing towards outpatient total hip arthroplasty (THA), methods to adequately manage postoperative pain is of paramount importance.
- Trial name
- PENG (NCT04729686)
- Testing
- Pericapsular Nerve Block, Fascia Iliaca Nerve Block
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- LifeBridge Health
Post-Op Complication
Tele-monitoring of Post Join Arthroplasty Outcomes: A Feasibility Study
The purpose of this study is to develop an effective telephone mediated follow-up system to reduce the number of unplanned readmissions and emergency department visits after total joint arthroplasty.
- Trial name
- NCT04586296
- Testing
- Telemedicine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis of Hip, Regional Anesthesia
Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement
The purpose of this research study is to evaluate the analgesic efficacy of adding a single shot parasacral (sciatic) nerve block to a continuous lumbar plexus block in patients undergoing total hip replacement.
- Conditions
- Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty
- Trial name
- NCT02161484
- Testing
- Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rita Merman
Pain, Postoperative, Opioid Overdose
Ultrasound-guided PENG Block in Total Hip Replacement
This randomized controlled study will be carried out on 60 adult patients undergoing primary total hip replacement in Tanta University Hospitals.
- Trial name
- NCT04984109
- Testing
- Real PENG block
- Where
- Egypt
- Volunteers
- 71 people
- Sponsor
- Tanta University
Arthroplasty, Replacement, Hip
Trident II Tritanium Acetabular Shell Outcomes Study
The purpose of this study is to review the performance and success rate of an FDA approved cementless hip replacement part called the Trident II Tritanium Acetabular Shell.
- Trial name
- NCT02999009
- Testing
- Trident II Tritanium Acetabular Shell
- Where
- 9 sites in United States
- Volunteers
- 383 people
- Sponsor
- Stryker Orthopaedics
Hip Fracture, Osteoarthritis
Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery
The purpose of this study is to determine the effects of two postoperative interventions designed to preserve muscle protein after major hip or knee surgery.
- Conditions
- Hip Fracture, Osteoarthritis, Femur Head Necrosis
- Trial name
- NCT00393848
- Testing
- Essential amino acid supplement, Ketoconazole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arkansas
Arthroplasty, Replacement, Hip
Trident® Tritanium™ Acetabular Shell Revision Study
The purpose of this study is to evaluate a hip implant system used when a previous hip replacement surgery has failed.
- Trial name
- NCT00535626
- Testing
- Trident® Tritanium™ Acetabular Shell
- Where
- 15 sites in United States
- Volunteers
- 241 people
- Sponsor
- Stryker Orthopaedics
Osteoarthritis, Degenerative Joint Disease
Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
The purpose of this study is to clarify the efficacy of a multidrug versus single drug periarticular injection when only standard operative and postoperative pain management protocols used and the control group is exposed to what…
- Trial name
- NCT03119038
- Testing
- Bupivicaine + epinephrine, Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Hip Arthroplasty Replacement
Changes in Perioperative Blood Volume and Fluid Distribution in Patients Undergoing Primary Total Hip Replacement.
Clinical assessment of bleeding and calculation of perioperative blood loss do not provide an accurate estimate of blood volume.
- Trial name
- NCT06888908
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Analgesics, Opioid, Anesthesia, Spinal
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Pain management after total hip replacement is one of the most important aspects of postoperative care for patients and clinicians alike.
- Conditions
- Analgesics, Opioid, Anesthesia, Spinal, Total Hip Replacement, Adverse Anesthesia Outcome
- Trial name
- NCT06878014
- Testing
- Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone
- Where
- 3 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Hip Osteoarthritis
Estimating VO2 Max and Recovery
The study aims to estimate VO2 max levels at pre- and post-operative timepoints before and after hip arthroplasty surgery, using non-exercise-based measurement methods.
- Trial name
- NCT06744582
- Testing
- VO2 max
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Bournemouth University
Arthroplasty, Replacement, Hip
MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve
Revision total hip replacement using a ceramic head utilizes a titanium sleeve which introduced another articulation into the system that may lead to a local soft tissue reaction.
- Trial name
- NCT05686915
- Testing
- MARS MRI, Titanium Labs, Cobalt Labs
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Colorado Joint Replacement