Clinical trials: Hip Replacement in Osteoarthritis Patients
Hip Osteoarthritis
Estimating VO2 Max and Recovery
The study aims to estimate VO2 max levels at pre- and post-operative timepoints before and after hip arthroplasty surgery, using non-exercise-based measurement methods.
- Trial name
- NCT06744582
- Testing
- VO2 max
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Bournemouth University
Hip Replacement in Osteoarthritis Patients
RSA Study of Furlong Evolution With and Without Collar
The aim of this study is to further investigate the clinical and radiological importance of design changes in cementless hip prosthesis.
- Trial name
- NCT01894854
- Testing
- Stem collar
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Osteoarthritis
Preoperative Exercise in Patients Undergoing Total Hip or Knee Replacement
This study is conducted in the Community Hospital in Svendborg (OUH Svendborg Sygehus) in collaboration with University of Southern Denmark and Odense University Hospital.
- Trial name
- NCT01003756
- Testing
- Preoperative neuromuscular exercise
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- University of Southern Denmark
Hip Arthrosis, Femur Head Necrosis
Difference in Return to Sports Activity After Hip Arthroplasty by THR or Resurfacing
This study aims to evaluate the return to activity in younger patients under 50 years old after undergoing either total hip replacement (THR) or hip resurfacing, as performed in everyday practice.
- Trial name
- PTH-50 (NCT06410079)
- Testing
- total hip replacement
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Société Française de chirurgie de la Hanche et du Genou
Hip Replacement in Osteoarthritis Patients, Osteoarthritis, Hip
Prehabilitation in Older People Undergoing Total Hip Replacement
The goal of this clinical trial is to determine the effect of Resistance Exercise Training (RET)-based (p)rehabilitation versus usual care on skeletal muscle mass and function, as well as on underlying biological processes, in…
- Trial name
- PREHIP (NCT07048080)
- Testing
- (P)rehabilitation Progresive Resistance Exercise Training, Prehabilitation Group Deuterated Water, Usual Care Group Deuterated Water
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- Universidad de La Frontera
Aortic Diseases, Osteoarthritis, Hip
Pro-inflammatory Cytokines in Blood From Orthopedic Surgery Compared to Abdominal Aneurysm Repair
The purpose of this study is to investigate the contents in blood sampled from surgery site during hip replacement compared with blood sampled from abdominal aortic surgery.
- Trial name
- KEEP-HB (NCT00851149)
- Testing
- Sangvia blood sampling system
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Sykehuset i Vestfold HF
Hip Osteoarthritis, Knee Osteoarthristis
The Outcome of Three Weeks Rehabilitation in Patients With a Total Hip or Knee Replacement Experiencing Persistent Physical Impairments
Patients with total hip or knee replacement experiencing persistant problems are offered 3 weeks of intensive rehabilitation.
- Trial name
- Rehab-hip-knee (NCT07105657)
- Testing
- Rehabilitation
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Horsens Hospital
Hip Injuries, Coxarthrosis
Balance and Leg Function After Hip Replacement
Task-oriented leg exercise are commonly used after joint surgeries in various hip pathologies. Based on this theory, it was hypothesized that task-oriented exercise without conventional physiotherapy can have better result in…
- Conditions
- Hip Injuries, Coxarthrosis, Hip Replacement
- Trial name
- NCT05343195
- Testing
- Task-oriented exercise, Control
- Where
- Lithuania
- Volunteers
- 40 people
- Sponsor
- Lithuanian Sports University
Osteoarthritis, Hip, Total Hip Arthroplasty
Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With OA
Aim: To compare the effect of one single dose versus multiple doses of prophylactic antibiotics administered within 24 hours, on the development of PJI in patients with osteoarthritis undergoing primary THA.
- Conditions
- Osteoarthritis, Hip, Total Hip Arthroplasty, Prosthetic-joint Infection
- Trial name
- ProHipQ-OA (NCT05530551)
- Testing
- Antibiotic dosage practice
- Where
- 36 sites in Denmark
- Volunteers
- 20,000 people
- Sponsor
- Soren Overgaard
Osteoarthritis
Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery
The investigators are testing the hypothesis that administering 2L of body temperature warmed lactated ringer's intravenously prior to surgery can optimize the postoperative and recovery of patients undergoing total hip and total…
- Trial name
- Hydration (NCT02638623)
- Testing
- Lactated Ringer
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Osteoarthritis, Arthritis
A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, Compared With Placebo in Patients With Osteoarthritis
The purpose of the study is to determine if fentanyl, delivered through the skin via an adhesive patch, has a superior pain-relieving effect compared with placebo in patients with osteoarthritis pain that is inadequately…
- Trial name
- NCT00236366
- Testing
- fentanyl
- Volunteers
- 418 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Arthritis, Degenerative
Pilot Study Evaluating the Safety and Efficacy of a New Hard-on-Hard Total Hip Replacement System
The purpose of this study is to assess the early and long term safety and efficacy of the hard-on-hard total hip replacement system (R3 ODH-ODH utilization) in patients with non-inflammatory arthritis.
- Trial name
- NCT02154516
- Testing
- ODH Hip System
- Where
- 2 sites in South Africa
- Volunteers
- 26 people
- Sponsor
- Smith & Nephew, Inc.
Hip Osteoarthritis
Minimal Invasive Surgery in Total Hip Arthroplasty Patients; Strength, Functionality and Post Operative Complications
The aim of the present study is to explore the most efficient surgical approach in total hip replacement in short and long term when concerning strength, functionality and postoperative complications.
- Trial name
- NCT01959360
- Testing
- Direct lateral, minimal invasive, modified minimal invasive
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Norwegian University of Science and Technology
Hip Implant, Hip Replacement in Osteoarthritis Patients
Radiographic Migration Analysis of the Insignia Hip Stem
The purpose of this study is to assess the migration pattern of the Insignia hip stem using radiostereometric analysis (RSA for short) and computed tomography (CT).
- Conditions
- Hip Implant, Hip Replacement in Osteoarthritis Patients, Migration of Implant
- Trial name
- NCT06696313
- Testing
- Insignia
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Canadian Radiostereometric Analysis Network
Hip Replacement, Total, Osteonecrosis of Femoral Head
Ultra-Short Anatomic and Conventional Cementless Stems Cementless Stems in Patients Younger Than Fifty-Five Years Old
As clinical and radiographic performance of an ultra-short anatomic cementless stem have been investigated only two randomized controlled studies, well-designed trials should aim for a thorough comparison of the outcomes of…
- Conditions
- Hip Replacement, Total, Osteonecrosis of Femoral Head, Coxarthrosis
- Trial name
- NCT02338596
- Testing
- Total hip replacement
- Volunteers
- 111 people
- Sponsor
- Ewha Womans University
Osteoarthritis
Effect of Exercise as Non-surgical Treatments on Time to Total Hip Replacement Surgery
The aim of this trial is to test the hypothesis that patients with severe hip osteoarthritis postpone time to hip replacement surgery following participation in a patient education and supervised exercise program when compared to…
- Trial name
- HipSPORT (NCT01697241)
- Testing
- Supervised exercise, Patient education
- Where
- 2 sites in Denmark
- Volunteers
- 110 people
- Sponsor
- University of Southern Denmark
Hip Osteoarthritis, Heterotopic Ossification
Balance in Patients With Ectopic Bone Tissue After Total Hip Replacement
One of the typical complications which occurs after total hip replacement (THR) procedure is heterotopic ossification (HO). According to current studies abnormal formation of bone after trauma or replacement of the hip could…
- Conditions
- Hip Osteoarthritis, Heterotopic Ossification, Hip Arthropathy
- Trial name
- NCT05218954
- Testing
- Biomechanical analysis of risk fall
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Medical University of Warsaw
Arthroplasty, Osteoarthritis
Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery Recovery
The purpose of this study is to assess the effectiveness of a preoperative muscle training program on hip or knee TJA (Total Joint Arthroplasty).
- Trial name
- NCT03483519
- Testing
- Rehabilitation, Standard of Care
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Total Hip Arthroplasty (THA), Total Knee Arthroplasty (TKA)
Molecular Mechanisms Underlying Hip and Knee Osteoarthritis in Patients Undergoing Primary Elective Arthroplasty
The aim of this observational study is to determine content of rare metals and other elements, along with the levels of selected immunological parameters, in the tissue of the hip or knee joint in the course of degenerative…
- Conditions
- Total Hip Arthroplasty (THA), Total Knee Arthroplasty (TKA), Hip Osteoarthritis, Knee Osteoarthristis
- Trial name
- NCT07347821
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis of Hip, Regional Anesthesia
Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement
The purpose of this research study is to evaluate the analgesic efficacy of adding a single shot parasacral (sciatic) nerve block to a continuous lumbar plexus block in patients undergoing total hip replacement.
- Conditions
- Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty
- Trial name
- NCT02161484
- Testing
- Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rita Merman