Clinical trials: Hip Surgeries
Osteomyelitis
Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
This is a research study designed to look at the efficacy and safety of daptomycin given at a dose of 6 mg/kg or 8 mg/kg in subjects being treated for prosthetic hip or knee infections caused by Staphylococci.
- Trial name
- NCT00428844
- Testing
- daptomycin, vancomycin, teicoplanin
- Where
- 26 sites in United States, Russia and 1 more
- Volunteers
- 75 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Thrombosis, Venous
Total Hip Replacement Study Of GSK576428 (Fondaparinux Sodium)
This study is requested by PMDA to confirm the optimal dose for THR (total hip replacement).
- Trial name
- NCT00320398
- Testing
- Fondaparinux
- Volunteers
- 114 people
- Sponsor
- GlaxoSmithKline
Osteoarthritis, Rheumatoid Arthritis
Anterior Advantage With KINCISE
This is a post-market prospective, 1:1 randomized, multicenter non-inferiority study to compare the femoral broaching time for THA with the Anterior Advantage approach with KINCISE vs. without KINCISE.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post Traumatic Arthritis
- Trial name
- NCT04191733
- Testing
- KINCISE(TM) Surgical Automated System
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- DePuy Orthopaedics
Orthopedic Disorder
Comparative Evaluation of Lumbar Plexus and Suprainguinal Fascia Iliaca Compartment Blocks
The investigators aim to compare the use of a suprainguinal fascia iliaca compartment block vs lumbar plexus block as an adjunct to general anesthesia in pediatric patients undergoing orthopedic procedures involving the hip or…
- Trial name
- NCT03746951
- Testing
- Ropivacaine Hcl 0.5% Inj Vil 20Ml
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Nationwide Children's Hospital
Post Operative Analgesia
The Ultrasound Guided Pericapsular Nerve Group and Anterior Quadratus Lumborum Blocks in Hip Replacement Surgeries
The investigators hypothesis that PENG block will produce effective opioid sparing analgesia with enhanced motor recovery more than AQLB in elderly patients undergoing total hip replacement surgeries
- Trial name
- NCT06679764
- Testing
- Anterior quadratus lumborum block technique (AQLB), Pericapsular Nerve Group (PENG) block, Control Group
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University
Thrombosis, Hip Replacement
A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery
This study is to assess if DU176b is effective in prevention of blood clots following hip replacement surgery. The duration is 7-10 days of treatment and 30 and 60 day follow-up visits.
- Trial name
- NCT00398216
- Testing
- DU176b - action is the prevention of venous thromboembolism by the use of a Factor Xa inhibitor
- Where
- 29 sites in United States, Canada and 5 more
- Volunteers
- 903 people
- Sponsor
- Daiichi Sankyo
Hip Fractures, Delirium
Post-Operative Delirium in Elderly Surgical Patients
This research is being done to see what effects sedative drugs during surgery have on peoples' thinking processes after they wake up.
- Trial name
- STRIDE (NCT00590707)
- Testing
- Deeper sedation, Moderate sedation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Pain, Postoperative
Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery
Surgical trauma causes nerve sensitization leading to amplification and prolongation of postoperative pain. In experimental studies, pre-injury neural blockade using local anesthetics has been shown to reduce post-injury…
- Trial name
- NCT01693900
- Testing
- Pre-operative Ultrasound FICB Group, Intra-operative FICB Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Randy Fayne, DO
Inguinal Hernia, Pelvic Fracture
Corona Mortis in Patients Undergoing TEP for Inguinal Hernia
This study aim to describe the presence, type and size of Corona mortis (CMOR) in patients undergoing total extraperitoneal (TEP) inguinal hernia repair procedures.
- Conditions
- Inguinal Hernia, Pelvic Fracture, Acetabular Fracture, Bleeding
- Trial name
- NCT04303442
- Testing
- TEP
- Where
- Bulgaria
- Volunteers
- 300 people
- Sponsor
- Sofia Med Hospital
Postoperative Complications, Hip Fracture
A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia
This pilot project will address the gaps in knowledge regarding the effect of anesthetic technique on the risk of delirium through an adequately-powered trial employing standardized regimens for treatment and outcome assessment…
- Conditions
- Postoperative Complications, Hip Fracture, Delirium
- Trial name
- NCT02190903
- Testing
- General endotracheal anesthesia, Regional (spinal) Anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Delirium
Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period
Delirium (acute confusion) is a highly prevalent condition among hospitalized elders with substantial morbidity within the hospital and beyond.
- Trial name
- SHARP (NCT00586196)
- Testing
- donepezil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Beth Israel Deaconess Medical Center
Digital Block
Comparison of Three Methods of Hemoglobin Monitoring
This study will further investigate the Masimo SpHb [FDA Approved] continuous non-invasive hemoglobin monitor in spine surgery patients.
- Trial name
- NCT01284296
- Testing
- Lidocaine digital block, Masimo SpHb continuous hemoglobin monitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Venous Thromboembolism
BIBR 1048 Dose Range Finding Study in Prevention of Venous Thromboembolism in Patients With Primary Elective Total Hip or Knee Replacement Surgery
The primary objective of this study is to establish the dose-response relationship with regard to efficacy and safety of BIBR 1048 (50 mg bis in die(b.i.d), 150 mg b.i.d, 225 mg b.i.d.
- Trial name
- NCT01225822
- Testing
- Enoxaparin, BIBR 1048
- Where
- 59 sites in Austria, Belgium and 10 more
- Volunteers
- 1,973 people
- Sponsor
- Boehringer Ingelheim
Fracture Healing
Study To Assess FRacTure Healing With SclerosTin Antibody - Hip
This is an international, multi-center study to determine the efficacy, safety, and tolerability of romosozumab (AMG 785) in adults with a fresh unilateral hip fracture, status post surgical fixation.
- Trial name
- STARTT-Hip (NCT01081678)
- Testing
- Romosozumab
- Where
- 99 sites in United States, Argentina and 22 more
- Volunteers
- 332 people
- Sponsor
- Amgen
Venous Thromboembolism, Arthroplasty, Replacement
Pradaxa (Dabigatran Etexilate) VTE Prevention After Elective Total Hip or Knee Replacement Surgery
an open, prospective, observational study to collect data on safety (major bleeding events) and efficacy (symptomatic venous thromboembolism(VTE)) of a switch from Enoxaparin to dabigatran etexilate in patients with total knee…
- Trial name
- NCT01153698
- Testing
- dabigatran
- Where
- 7 sites in Austria
- Volunteers
- 167 people
- Sponsor
- Boehringer Ingelheim
Post Operative Pain
Efficacy and Safety Trial to Evaluate the Sufentanil NanoTab® PCA System/15 mcg (Zalviso™) for Post-Operative Pain in Patients After Knee or Hip Replacement Surgery
The purpose of this study is to compare the efficacy and safety of the Sufentanil NanoTab PCA System/15 mcg to the Placebo Sufentanil NanoTab PCA System for the management of acute moderate to severe post-operative pain after…
- Trial name
- NCT01660763
- Testing
- Sufentanil NanoTab PCA System/15 mcg
- Where
- United States
- Volunteers
- 419 people
- Sponsor
- Talphera, Inc
Surgery, Hip Osteoarthritis
Two Year Study With Robotic-Arm Assisted Hip Surgery.
This study will involve a quantitative assessment of prospectively collected computed tomography, radiographic and patient outcomes data from multiple centers.
- Trial name
- NCT03891199
- Testing
- Robotic-Arm Assisted THA
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Surgery
Quadratus Lumborum Block for Analgesia Following Hip Arthroscopy
Evaluate difference in postoperative opiate consumption when patients do or do not receive a quadratus lumborum block preoperatively for hip arthroscopy.
- Trial name
- NCT03557125
- Testing
- QL Block, Saline Skin Wheel
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-Operative Pain
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
The study is intended to show that the Sufentanil NanoTab PCA System is as effective as morphine intravenous patient-controlled analgesia (IV PCA) for treating pain after surgery.
- Trial name
- NCT01539538
- Testing
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Where
- 16 sites in United States
- Volunteers
- 357 people
- Sponsor
- Talphera, Inc
Muscle Wasting (Atrophy) After Hip Fracture Surgery
Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery
The purpose of this study was to assess if bimagrumab is safe and effective in patients with muscle wasting (atrophy) after hip fracture surgery.
- Trial name
- NCT02152761
- Testing
- bimagrumab
- Where
- 53 sites in United States, Argentina and 17 more
- Volunteers
- 251 people
- Sponsor
- Novartis Pharmaceuticals