Clinical trials: Hip Surgery
Pain, Postoperative
Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery
Surgical trauma causes nerve sensitization leading to amplification and prolongation of postoperative pain. In experimental studies, pre-injury neural blockade using local anesthetics has been shown to reduce post-injury…
- Trial name
- NCT01693900
- Testing
- Pre-operative Ultrasound FICB Group, Intra-operative FICB Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Randy Fayne, DO
Post-Operative Pain
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
The study is intended to show that the Sufentanil NanoTab PCA System is as effective as morphine intravenous patient-controlled analgesia (IV PCA) for treating pain after surgery.
- Trial name
- NCT01539538
- Testing
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Where
- 16 sites in United States
- Volunteers
- 357 people
- Sponsor
- Talphera, Inc
Hip Surgery Corrective
Fluid and Nutrition in Elective Hip Surgery
The purpose of this study is to determine whether fluid or glucose administration before hip replacement surgery minimizes postoperative muscle breakdown (catabolism), fatigue and disturbances in carbohydrate metabolism.
- Trial name
- NCT01211184
- Testing
- Water administration, carbohydrate drink, Fasting.
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sodertalje Hospital
Femoroacetabular Impingement
A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial
The purpose of this study is to compare the outcomes for patients that receive two different treatments used for FAI (Femoroacetabular Impingement).
- Trial name
- NCT01993615
- Testing
- Arthroscopic Surgery, Physical Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Madigan Army Medical Center
Pain, Postoperative
Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management
The purpose of this study is to compare two medications currently injected intra-operatively to help decrease pain after surgery in patients undergoing a primary total hip replacement (THR).
- Trial name
- NCT03001453
- Testing
- Liposomal Bupivacaine, 0.25% Bupivacaine with epinephrine, Saline
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- American Hip Institute
Sleep Apnea, Obstructive
Prevalence of Sleep Apnea in Patients Presenting for Hip or Knee Replacement Surgery
The study hypothesis is that the prevalence of obstructive sleep apnea in patients presenting for total knee or total hip arthroplasty is higher than generally suspected.
- Trial name
- NCT00874822
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- University of Nebraska
Arthroplasty, Replacement, Thromboembolism
Pradaxa (Dabigatran Etexilate) 150 mg/q.d. in Patients With Moderate Renal Impairment After Hip or Knee Replacement Surgery
An observational cohort study on safety and efficacy to generate additional data on the benefit/risk profile of the 150 mg dose of Pradaxa in patients with renal impairment
- Trial name
- NCT00847301
- Where
- 53 sites in Austria, France and 5 more
- Volunteers
- 472 people
- Sponsor
- Boehringer Ingelheim
Arthroplasty, Replacement, Hip
Visibility of Site Marking for Surgical Time Out With Two Different Skin Preparation Solutions
Skin preparation solutions are used to clean the skin of the patient before surgery to decrease the rate of infection. This is particularly important for hip replacement to reduce the risk of prosthetic joint infection.
- Trial name
- site marking (NCT00739583)
- Testing
- CHG 2% w/v and IPA 70% v/v, Iodophor 0.7% and IPA 74% w/w
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Dysplasia; Hip
Biomechanical Reconstruction of Three Different Hip Stem Designs in Hip Dysplasia Using a 3D CT-based Planning Software
A random population of 200 CT scans of pelvis and thigh in an adult population affected by hip dysplasia will be selected. The aim of this study is to evaluate the biomechanical reconstruction of the hip anatomy provided by three…
- Trial name
- CTdevice (NCT04904640)
- Testing
- Hip stem
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
Thromboembolism, Arthroplasty, Replacement, Hip
Study to Evaluate the Safety and Efficacy of Pradaxar for the Prevention of Venous Thromboembolism in the Mexican Population Undergoing Elective Total Hip or Knee Replacement Surgery
Open, prospective, uncontrolled, observational cohort study.
- Trial name
- NCT00967447
- Where
- 28 sites in Mexico
- Volunteers
- 2 people
- Sponsor
- Boehringer Ingelheim
Surgery
Quadratus Lumborum Block for Analgesia Following Hip Arthroscopy
Evaluate difference in postoperative opiate consumption when patients do or do not receive a quadratus lumborum block preoperatively for hip arthroscopy.
- Trial name
- NCT03557125
- Testing
- QL Block, Saline Skin Wheel
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Tranexamic Acid Dosing for Major Joint Replacement Surgery
Over 1.7 million hip and knee replacements are performed every year worldwide. These surgeries are associated with high blood loss and transfusion rates. In older patients, the high blood loss can result in postoperative anemia.
- Trial name
- TXA-Dosing (NCT05075200)
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Sunnybrook Health Sciences Centre
Neuromuscular Blockade, Arthroplasty, Replacement, Hip
Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)
This study will assess the effect of reversal of neuromuscular blockade with sugammadex compared with reversal according to usual care (neostigmine or spontaneous reversal) on the incidence of post-surgical bleeding events and on…
- Conditions
- Neuromuscular Blockade, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Blood Coagulation
- Trial name
- NCT01422304
- Testing
- Sugammadex, neostigmine and glycopyrrolate or atropine
- Volunteers
- 1,198 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoarthritis
General or Regional Anesthesia for Hip Surgery
The purpose of this study is to determine whether general anaesthesia or regional anaesthesia is best for patients undergoing Total Hip Arthroplasty.
- Trial name
- NCT01733472
- Testing
- GA-arm, remifentanil, RA-arm
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Arthroplasty, Replacement, Hip, Blood Transfusion
Comparison in Need for Bank Blood Between Patients Undergoing Total Hip Surgery That Either Receive Their Own Blood Back or Not
The study is a prospective, controlled, randomised and assessor blind study that investigate if the need for bank blood transfusion could be reduced in patients, undergoing primary or revision total hip replacement surgery, who…
- Conditions
- Arthroplasty, Replacement, Hip, Blood Transfusion, Blood Transfusion, Autologous
- Trial name
- NCT00822588
- Testing
- Sangvia® System
- Where
- 6 sites in Austria, Netherlands and 2 more
- Volunteers
- 227 people
- Sponsor
- Wellspect HealthCare
Hip Osteoarthritis
Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
The Lumbar Plexus (LP) block is currently used as the standard-of-care regional anesthesia technique to provide postoperative pain management after primary hip replacement surgery at UPMC Shadyside Hospital.
- Trial name
- NCT03801265
- Testing
- Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Sharad Khetarpal
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Hip Surgery Corrective, Knee Injuries
Prospective, Randomized Clinical Investigation of Two Different Postoperative Wound Dressings
The primary objective of this investigation is to evaluate if complications related to surgical wound are more common in the treatment group compared to the control group starting from operation day until last visit.
- Trial name
- MxBPo02 (NCT02653183)
- Testing
- Active Comparator: Aquacel Surgical, Experimental: Mepilex Border Post-Op
- Where
- 3 sites in Belgium, Sweden
- Volunteers
- 118 people
- Sponsor
- Molnlycke Health Care AB
Total Hip Replacement
Effect of Steroids on Thrombosis (Blood Clot Formation) and Inflammation in Patients Undergoing Hip Surgery
Studies have shown that surgery causes some reactions in your body consistent with inflammation. When the inflammation is extensive, it may affect different parts of the body including the lungs.
- Trial name
- NCT01782859
- Testing
- Prednisone, Hydrocortisone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hip Fractures, Hip Arthropathy
Optimizing Cerebral Autoregulation During Surgery
The purpose of this study is to conduct a pilot trial to determine the feasibility, safety, and potential efficacy of targeting mean arterial blood pressure (MAP) within the limits of cerebral autoregulation during surgery…
- Conditions
- Hip Fractures, Hip Arthropathy, Surgery, Delirium
- Trial name
- NCT05308290
- Testing
- Blood pressure management according to cerebral autoregulation, Blood pressure management according to usual care
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University