Clinical trials: Hispanic
Myotonic Dystrophy 1, DM1
The Spanish National Registry for Myotonic Dystrophy Type 1
Myotonic Dystrophy Type 1 (DM1) is a rare genetic neuromuscular condition that can affect multiple organs and varies widely in how it presents.
- Conditions
- Myotonic Dystrophy 1, DM1, Myotonic Dystrophy Type 1, Myotonic Dystrophy, Congenital
- Trial name
- DM1-Hub (NCT07385443)
- Testing
- Patient Registry
- Where
- 8 sites in Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Dyslipaemia, Atherosclerosis Risk
Dyslipaemia, Atherosclerosis Risk and Increased hsCRP and Inflammatory and Oxidative Status in the Spanish Population. Database Analysis of Previous Studies Performed in Spain
The present project is aimed at determining the prevalence of LDL-C <130 mg/dl with hsCRP ≥2mg/l, and of HDL-C < 40 mg/dl in Spain together with the estimation of cardiovascular risk, to analyze the contribution of measuring…
- Conditions
- Dyslipaemia, Atherosclerosis Risk, Increased hsCRP, Inflammatory and Oxidative Status in the Spanish Population
- Trial name
- DARIOS (NCT00998062)
- Where
- 11 sites in Spain
- Volunteers
- 30,181 people
- Sponsor
- AstraZeneca
Auditory Processing Disorder
Auditory Processing in Spanish-English Bilinguals: Is Performance Better When Tested in Spanish or English?
The purpose of this study is to learn more about how bilingual individuals process sound in challenging listening environments and how testing language may impact results on auditory processing assessments.
- Trial name
- NCT05452486
- Testing
- English APD assessment, Spanish APD assessment
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Multiple Chronic Conditions, Dementia
Patient Priorities Care for Hispanics With Dementia
Most persons living with dementia (PlwD) have multiple chronic conditions (MCC). Managing MCC typically involves adhering to clinical practice guidelines for single diseases.
- Trial name
- PPC-HD (NCT05303194)
- Testing
- Patient Priorities Care (PPC) Approach, Adapted PPC
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Breast Cancer, Ductal Breast Carcinoma in Situ
Bilingual Breast Cancer Educational Intervention for Hispanic Women With Stage I, Stage II, or Stage III Breast Cancer and Their Families or Caregivers
RATIONALE: Studying quality-of-life in patients having cancer treatment may identify the intermediate- and long-term effects of treatment on patients with cancer PURPOSE: This randomized clinical trial is studying how well an…
- Conditions
- Breast Cancer, Ductal Breast Carcinoma in Situ, Stage I Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT01043003
- Testing
- educational intervention, quality-of-life assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Hepatitis C
Effectiveness, Safety and Clinical Outcomes of Elbasvir/Grazoprevir: Results From a Spanish Real World Cohort
This is a multicentre, descriptive, observational and ambispective study carried out in patients who are treated with Elbasvir/Grazoprevir in hospitals that included their data in Hepa-C Registry (directed by the Spanish…
- Trial name
- NCT03111966
- Testing
- Spanish cohort with HCV treated in real practice with Elbasvir/Grazoprevir
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Hepa C
HIV/AIDS, Cancer
Web-Based Cognitive Behavioral Stress Management for Latino Sexual Minority Men Living With HIV and Cancer
This is a one year study to develop and test a culturally-tailored, web-based cognitive behavioral stress management (CBSM) intervention for Latino sexual minority men living with both HIV and cancer.
- Trial name
- C-SmartManage (NCT03993054)
- Testing
- Culturally-tailored cognitive behavioral stress management
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Miami
HIV
Cognition Metabolism and Exercise Among Women Living With HIV in Puerto Rico
The study evaluates the association between soluble insulin receptor dysfunction, cardiorespiratory fitness, and HIV associated neurocognitive disorder (HAND).
- Trial name
- CMEx (NCT02962622)
- Testing
- High intensity interval training (HIIT)
- Where
- Puerto Rico
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Diabetes Mellitus, Type 2, Glucose Metabolism Disorders (Including Diabetes Mellitus)
Comparison of Oral Semaglutide w/ Placebo- Treatment for Latino Adults w/T2 Diabetes Receiving Enhanced Lifestyle Care
Researchers at Sansum Diabetes Research Institute want to learn more about how taking a new approved drug called oral Semaglutide, while eating fresh vegetables, impacts health in Hispanic/Latino adults with type 2 diabetes.
- Trial name
- NCT04938388
- Testing
- Semaglutide Pill, Fresh organic vegetables
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Sansum Diabetes Research Institute
SARS-CoV-2, Covid19
Protecting Our Community: COVID-19 Testing
The COVID-19 pandemic has disproportionately affected American Indian (AI) and Latino communities, and these groups also have increased risk of poor prognosis due to high rates of chronic disease such as diabetes, cardiovascular…
- Trial name
- NCT04866303
- Testing
- Home-based SARS-CoV-2 test kit
- Where
- 2 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Montana State University
Nutrition, Healthy, Knowledge, Attitudes, Practice
Pilot Study of Capacity-oriented Intervention to Promote Food Security and Diet Quality Among Hispanics/Latinos
Despite a large proportion exhibiting cardiovascular disease risk factors and experiencing food insecurity, U.S. Hispanics/Latinos demonstrate low cardiovascular mortality, which may indicate existing capital (e.g., assets)…
- Conditions
- Nutrition, Healthy, Knowledge, Attitudes, Practice, Self Efficacy
- Trial name
- NCT05623202
- Testing
- Multi-level behavior-change intervention to strengthen food- and diet-related capital to promote food security and diet quality among low-income Hispanic/Latino adults
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Prostate Cancer, Cancer
Adaptation of the American Cancer Society (ACS) Early Detection of Prostate Cancer Patient Decision Aid for Spanish Speaking Men
Objectives: The primary objective of this project is to develop and evaluate a Spanish-language slide set for administration in group settings, adapted from the content of the current guidelines and existing, self-administered…
- Trial name
- NCT01447186
- Testing
- Post-Test Questionnaire, Interviews, Focus Groups
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Severe Aortic Valve Stenosis
MYLEAD Spanish Prospective Registry
Investigator-initiated, prospective, multicentre registry, whose objectives are: 1/ to evaluate the incidence of conduction defects and the need of pacemaker implantation post-procedure, at discharge, at 30 days and at 1 year…
- Trial name
- MYLEAD (NCT06917066)
- Testing
- TAVR
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Alzheimer Disease, Frontotemporal Degeneration (FTD)
PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia
Caregivers of individuals with Alzheimer's disease and related dementia rarely get the preparation or training they need to manage their caregiving responsibilities and to successfully balance their own self-care and their…
- Conditions
- Alzheimer Disease, Frontotemporal Degeneration (FTD), Lewy Body Dementia (LBD), Vascular Contributions to Cognitive Impairment and Dementia (VCID)
- Trial name
- NCT04748666
- Testing
- Problem Solving Training
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Microvessels, Carbohydrate Metabolism
Cardiometabolic and Mental Health in the RGV
Microvascular insulin resistance has been shown to precede myocyte insulin resistance and impairments in metabolic function. However, there is no convincing data showing the relationship between impaired microvascular flow and…
- Conditions
- Microvessels, Carbohydrate Metabolism, Diabetes Mellitus, Type 2
- Trial name
- NCT03436875
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Rio Grande Valley
Hodgkin Disease, Lymphoma, T-Cell, Cutaneous
A Spanish Medical Record Review of Adults With Relapsed or Refractory CD30+ Malignancies When Re-treated With Brentuximab-vedotin
Participants in the study are adults with CD30-positive malignancies which include classical Hodgkin lymphoma (cHL), cutaneous T-cell lymphoma (CTCL): mycosis fungoides (MF) or primarily cutaneous anaplastic large cell lymphoma…
- Trial name
- BELIEVE (NCT04998331)
- Testing
- No Intervention
- Where
- 30 sites in Spain
- Volunteers
- 51 people
- Sponsor
- Takeda
Breast Cancer
Adherence of Hispanic / Latina Breast Cancer - Patients to Adjuvant Aromatase Inhibitors
This is an observational trial designed to assess prospectively the adherence rate to AIs among women with invasive breast cancer (stages I-III) currently receiving AI adjuvant therapy after standard local and systemic therapy.
- Trial name
- ALPA (NCT03144037)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Hospital Discharge
Tools to Improve Discharge Equity (TIDE) Pilot RCT
The investigators will test the impact of a package of linguistically appropriate discharge teaching tools against current standard of care for patients with Limited English proficiency (LEP) in an unblinded randomized controlled…
- Trial name
- TIDE (NCT05988229)
- Testing
- Toolkit to improve discharge equity
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Boston Medical Center
Obesity, Dental Caries
Nutrition Knowledge for Spanish-speaking Parents
Providing child nutrition information is a major goal of every pediatric well-child visit. Unfortunately, due to a wide array of issues, doing this effectively during clinic visits is challenging and insufficient.
- Trial name
- NCT01296945
- Testing
- Kiosk, paper, Kiosk PLUS paper
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pregnancy in Adolescence, Rural Health
Latino Teen Pregnancy Prevention K23
The study will utilize an exploratory study design, applying formative research methods to inform the development and pilot testing of an unintended teen pregnancy prevention intervention.
- Conditions
- Pregnancy in Adolescence, Rural Health, Hispanic or Latino
- Trial name
- NCT06105905
- Testing
- Healthy futures ("Futuros Saludables")
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
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