Clinical trials: HoLEP
Lower Urinary Tract Symptoms Caused by Benign Prostatic Enlargement (LUTS BPE), Prostate Artery Embolisation (PAE)
ROPE Registry Project to Determine the Safety and Efficacy of Prostate Artery Embolisation (PAE) for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Enlargement (LUTS BPE).
This is a study protocol for the UK ROPE Register for Lower Urinary Tract Symptoms (LUTS). This register enables us to collect data on the treatment of LUTS using prostate artery embolisation (PAE), and other surgical methods to…
- Conditions
- Lower Urinary Tract Symptoms Caused by Benign Prostatic Enlargement (LUTS BPE), Prostate Artery Embolisation (PAE), Transurethral Resection of the Prostate (TURP), Open Prostatectomy
- Trial name
- UKROPE (NCT02849522)
- Testing
- Prostatic Artery Embolisation, TURP, Open prostatectomy
- Volunteers
- 300 people
- Sponsor
- Cedar, United Kingdom
Benign Prostatic Hyperplasia
Thulium Fiber Laser Enucleation of the Prostate (TFLEP) vs HoLEP With Moses Technology (m-HoLEP)
Enucleation of the prostate equips technology (usually laser) to effectively treat lower urinary tract symptoms associated with benign prostate hyperplasia (BPH).
- Trial name
- NCT04807296
- Testing
- TFLEP, m-HoLEP
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Prostatic Hyperplasia, Benign
Impact of Long-term Dutasteride Use on Perioperative Outcomes of HoLEP
This study aims to investigate the effects of long-term dutasteride use (a 5-alpha reductase inhibitor) on surgical outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP) for benign prostatic…
- Trial name
- NCT07417449
- Testing
- Dutasteride, Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Ankara City Hospital Bilkent
Benign Prostatic Hyperplasia
Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life.
- Trial name
- HoLEP and TURP (NCT07663097)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Transurethral Resection of the Prostate (TURP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Holep Surgery, Pelvic Floor Exercises
The Effect of Pelvic Muscle Exercises on Urinary Incontinence in Patients Undergoing HoLEP Surgery.
Patients meeting the eligibility criteria and scheduled for HoLEP surgery will provide written informed consent prior to enrollment. Participants will be randomly assigned to either the intervention or control group.
- Conditions
- Holep Surgery, Pelvic Floor Exercises, Urinary Incontinence
- Trial name
- NCT07719036
- Testing
- pelvic exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Atlas University
Prostate Hyperplasia, Prostatic Hypertrophy
Low Energy HoLEP on IPSS
The purpose of this study is to prove that low-energy (30W) Holmium laser prostatectomy (Holeb) is not inferior to high-energy (100W) Holmium laser prostatectomy (safety and effectiveness)
- Conditions
- Prostate Hyperplasia, Prostatic Hypertrophy, Surgery, Bladder Outlet Obstruction
- Trial name
- NCT04514718
- Testing
- Holmium laser
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Benign Prostatic Hyperplasia
A Prospective, Multicenter, Open-label Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP)
Robotic assisted surgery for benign prostatic hyperplasia (BPH)
- Trial name
- NCT06668142
- Testing
- Beacon Platform
- Where
- 3 sites in Chile, New Zealand
- Volunteers
- 54 people
- Sponsor
- Andromeda Surgical
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Water Vapor Thermal Therapy Versus Ejaculation-Preserving HoLEP for Benign Prostatic Hyperplasia
This prospective comparative study will evaluate Water Vapor Thermal Therapy (Rezum) versus ejaculation-preserving Holmium Laser Enucleation of the Prostate (EP-HoLEP) in sexually active men with symptomatic benign prostatic…
- Trial name
- NCT07648875
- Testing
- Water Vapor Thermal Therapy, Ejaculation-Preserving Holmium Laser Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Benign Prostate Hypertrophy(BPH), Lower Urinary Track Symptoms
Comparison of Holmium Laser Enucleation of the Prostate and Robotic Water Jet Ablation for Benign Prostatic Hyperplasia
This study compares two FDA-approved surgical treatments for benign prostatic hyperplasia (BPH): Holmium Laser Enucleation of the Prostate (HoLEP) with MOSES 2.0 technology and Robotic Water Jet Ablation (RWJA) using the Hydros…
- Trial name
- NCT07772232
- Testing
- Device - HoLEP with MOSES 2.0, RWJA with Hydros Robotic System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Methodist Hospital Research Institute
Benign Prostate Hyperplasia, Lower Urinary Tract Symptoms
HoLEP vs. Greenlight 532nm-laser PVEP vs. Bipolar TURP in Management of Moderate/ Large BPH
Most guidelines are not strict for recommending single treatment approach for Moderate to large prostate. In this study the investigators planned to test the Greenlight (532-nm) laser Photoselective Vapo-Enucleation of the…
- Trial name
- NCT02332538
- Testing
- 532nm-laser photoselective vapo-enucleation of the prostate), Holmium laser enucleation of prostate, Bipolar TURP
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Top-Down Holmium Laser Enucleation of the Prostate (HoLEP) vs the Traditional HoLEP for Treatment of Benign Prostatic Hyperplasia (BPH)
Benign prostatic hyperplasia (BPH), the non-malignant enlargement of the prostate gland, places pressure on the urethra and causes urination difficulties and bladder problems.
- Trial name
- NCT04391114
- Testing
- Traditional HoLEP, Top-Down HoLEP
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation
Intraoperative Lung Mechanics Changes During HoLEP Surgery
This study aims to evaluate changes in driving pressure and static lung compliance during HoLEP surgery and to investigate their relationship with surgical and perioperative factors.
- Conditions
- Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07607704
- Testing
- HoLEP surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Lower Urinary Tract Symptoms, Lower Urinary Tract Obstructive Syndrome
EEP in Patients With Urodynamically Proven DU/DA
The aim of this project is to create und evaluate a multicentral, retro-/prospective database for patients with urodynamically proven detrusor underactivity (DU) or acontractility (DA) secondary to a non-neurogenic aetiology, who…
- Conditions
- Lower Urinary Tract Symptoms, Lower Urinary Tract Obstructive Syndrome, Detrusor Underactivity, Detrusor Areflexia
- Trial name
- NCT06452927
- Testing
- Endoscopic enucleation of the prostate
- Volunteers
- 300 people
- Sponsor
- EEPiDuDa Study Group
Prostate Hyperplasia
Ejaculation Preservation After Laser Enucleation Prostate
A multicentre randomised controlled trial evaluating the benefit of median lobe preservation on the incidence of retrograde ejaculation during prostate enucleation by HoLEP.
- Trial name
- EPALEP (NCT05017285)
- Testing
- HoLEP with median lobe preservation, HoLEP classic
- Where
- France
- Volunteers
- 11 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Prostatic Hyperplasia, Benign, Prostatic Adenoma
Observational Study to Compare Two Prostate Laser Enucleation Techniques in Terms of Urinary Incontinence
Benign prostatic hypertrophy or prostatic adenoma is a benign tumour that develops in the central part of the prostate. Prostatic adenoma can result in the progressive appearance of a difficulty in evacuating the bladder or…
- Trial name
- ENUPLASMHO (NCT05157724)
- Testing
- PLASMA
- Where
- France
- Sponsor
- Elsan
BPH (Benign Prostatic Hyperplasia), HoLEP (Holmium Laser Enucleation of Prostate)
A Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP)
This single-arm study aims to evaluate the Beacon Platform, an advancement in urological surgery. The study will assess its intraoperative and postoperative outcomes.
- Trial name
- NCT07741656
- Testing
- Beacon Platform
- Where
- 5 sites in Bulgaria, Chile and 1 more
- Volunteers
- 50 people
- Sponsor
- Andromeda Surgical
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Efficacy Study of HoLEP and TURP on LUTS Secondary to BPH
The purpose of this study is to compare of Efficacy and Safety Between Holmium Laser Enucleation of the Prostate (HoLEP) and Transurethral Resection of the Prostate (TURP) on the Lower Urinary Tract Symptoms (LUTS) Secondary to…
- Trial name
- NCT00877669
- Testing
- Transurethral resection of the prostate, Holmium Laser Enucleation of the Prostate
- Where
- South Korea
- Volunteers
- 313 people
- Sponsor
- Samsung Medical Center
BPH With Urinary Obstruction, Male
HoLEP vs BPRP of a Large Volume BPH: a Randomised Controlled Trial
To compare bipolar resection versus holmium laser enucleation for management of large BPH.
- Trial name
- NCT04143399
- Testing
- holmium laser enucleation of the prostate, Bipolar resection of the prostate
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Cairo University
Benign Prostatic Hyperplasia
Slim Sheath 22F Holmium Laser Enucleation of the Prostate (HoLEP) vs 26 F Sheath HoLEP for BPH: RCT
Holmium laser enucleation of the prostate (HoLEP) is routinely performed with 24F, 26F, and 28F laser scopes. Proponents of larger caliber scopes suggest that the larger scope size allows for improved visualization, hemostasis…
- Trial name
- NCT06546865
- Testing
- 22F Sheath Size, 26F Sheath Size
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Enlarged Prostate (BPH), Benign Prostatic Hyperplasia
Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.
- Trial name
- NCT07632742
- Testing
- Magneto 150 holmium laser, Moses 2.0 holmium laser
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Northwestern University