Clinical trials: HoLEP, active
BPH (Benign Prostatic Hyperplasia), Incontinence, Urinary
Evaluation of the Impact of Preoperative Pelvic Floor Exercise on Incontinence After Laser Enucleation of the Prostate: a Feasibility Study.
The purpose of this study is to assess the acceptability and feasibility of including a pelvic floor muscle exercise program into the care provided to patients undergoing prostate enucleation, studying both patients and…
- Conditions
- BPH (Benign Prostatic Hyperplasia), Incontinence, Urinary, HoLEP, Pelvic Floor Muscle Exercise
- Trial name
- PPP (NCT07456345)
- Testing
- Pelvic Floor Muscle Exercise before and after surgery
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Holep Surgery, Pelvic Floor Exercises
The Effect of Pelvic Muscle Exercises on Urinary Incontinence in Patients Undergoing HoLEP Surgery.
Patients meeting the eligibility criteria and scheduled for HoLEP surgery will provide written informed consent prior to enrollment. Participants will be randomly assigned to either the intervention or control group.
- Conditions
- Holep Surgery, Pelvic Floor Exercises, Urinary Incontinence
- Trial name
- NCT07719036
- Testing
- pelvic exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Atlas University
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the Prostate
Holmium laser enucleation of the prostate (HoLEP) is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-HOLEP (NCT07892599)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Ahmed Ebrahim Zahran
BPH, Urinary Incontinence
Effect of Group Preoperative Pelvic Floor Training for HoLEP
The main goal of this study is to see if group pelvic floor training before surgery can help prevent urinary incontinence after Holmium laser enucleation of the prostate (HoLEP) surgery.
- Trial name
- NCT05719220
- Testing
- Group preoperative pelvic floor training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Water Vapor Thermal Therapy Versus Ejaculation-Preserving HoLEP for Benign Prostatic Hyperplasia
This prospective comparative study will evaluate Water Vapor Thermal Therapy (Rezum) versus ejaculation-preserving Holmium Laser Enucleation of the Prostate (EP-HoLEP) in sexually active men with symptomatic benign prostatic…
- Trial name
- NCT07648875
- Testing
- Water Vapor Thermal Therapy, Ejaculation-Preserving Holmium Laser Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Benign Prostatic Hyperplasia With Outflow Obstruction
Learning Curve of Tri-lobar HoLEP Versus En-bloc HoLEP
Several HoLEP techniques have been developed, with the conventional tri-lobar and the en-bloc approaches being the most commonly practiced.
- Trial name
- NCT07890103
- Testing
- Tri-lobar HoLEP, En-bloc HoLEP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom
A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
This study compares the safety and efficacy of three endoscopic enucleation techniques for large prostates (>100 mL) in patients with benign prostatic hyperplasia (BPH): Thulium Fiber Laser Enucleation (ThuFLEP), Holmium Laser…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom, Bladder Outlet Obstruction
- Trial name
- NCT07627178
- Testing
- Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP), Holmium Laser Enucleation of the Prostate (HoLEP), Bipolar Transurethral Enucleation of the Prostate (B-TUEP)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Post-Prostatectomy Urinary Incontinence, Benign Prostatic Hyperplasia
ExMI vs. Biofeedback PFMT for Post-Prostatectomy Incontinence
This study looks at whether adding a non-invasive magnetic stimulation treatment to standard pelvic floor exercises helps men regain bladder control faster after prostate surgery (HoLEP or bipolar enucleation).
- Trial name
- NCT07698028
- Testing
- Extracorporeal Magnetic Stimulation (ExMI), Pelvic Floor Muscle Training (PFMT)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
HoLEP, Trifecta Achievement
Predictors of Trifecta Achievement After HoLEP
Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment option for men experiencing bothersome lower urinary tract symptoms due to an enlarged prostate.
- Conditions
- HoLEP, Trifecta Achievement, Urinary Incontinence Following Surgical Procedure, Clavien Dindo Surgical Complication Scale
- Trial name
- ReMIUS-BPO (NCT07429994)
- Testing
- Transurethral Holmium Laser Enuclation of the Prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 604 people
- Sponsor
- Ondokuz Mayıs University
BPH, Lower Urinary Tract Symptoms
HoLEP Sexual Survivorship
The objective of this study is to evaluate how sexual function, ejaculatory function, and overall sexual satisfaction change following Holmium Laser Enucleation of the Prostate (HoLEP).
- Trial name
- NCT07660068
- Testing
- Telephone Interview, Questionnaires over the span of 24 months
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Northwestern University
HoLEP, Patient Satisfaction
Educational Discharge Video Impact on Post-Operative Healthcare Utilization After HoLEP
This will be a randomized interventional study. Patients scheduled to undergo a HoLEP at UCSF will be randomized into two groups after the procedure: one group will watch a scripted educational HoLEP video and the other group…
- Conditions
- HoLEP, Patient Satisfaction, Educational Video Intervention
- Trial name
- NCT06975033
- Testing
- Video
- Where
- 3 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of California, San Francisco
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
WATER III: Aquablation vs. Transurethral Laser Enucleation of Large Prostates (80 - 180mL) in Benign Prostatic Hyperplasia
Comparative analysis of efficacy and safety of Aquablation (AQUABEAM Robotic System®, PROCEPT BioRobotics, Redwood City, CA, USA) and transurethral laser enucleation as surgical therapy for benign prostatic hyperplasia with large…
- Trial name
- WATER III (NCT04801381)
- Testing
- Aquablation therapy, Transurethral laser enucleation
- Where
- 5 sites in Germany, United Kingdom
- Volunteers
- 202 people
- Sponsor
- University of Bonn
Prostatic Hyperplasia, Benign
Impact of Long-term Dutasteride Use on Perioperative Outcomes of HoLEP
This study aims to investigate the effects of long-term dutasteride use (a 5-alpha reductase inhibitor) on surgical outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP) for benign prostatic…
- Trial name
- NCT07417449
- Testing
- Dutasteride, Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Ankara City Hospital Bilkent
BPH
High-Frequency Irreversible Electroporation vs Standard of Care for Benign Prostatic Hyperplasia
The study aims to find a better surgical treatment for men with an enlarged prostate (Benign Prostatic Hyperplasia, or BPH) that effectively relieves urinary symptoms without sacrificing sexual function.
- Trial name
- NCT07572097
- Testing
- H-FIRE, Surgical Standard of Care (TURP or HoLEP)
- Volunteers
- 288 people
- Sponsor
- Shanghai East Hospital
BPH (Benign Prostatic Hyperplasia)
HoLEP-ThuLEP - Comparing Lasers for BPH Surgery
Benign prostatic hyperplasia (BPH) is a very common condition in older men. As the prostate enlarges, it can press on the urethra and make urination difficult.
- Trial name
- HOT (NCT07565961)
- Testing
- Thulium Laser Enucleation of the Prostate (ThuLEP), Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Benign Prostate Obstruction (BPO)
Enucleation Ratio as a Novel Predictor of Symptomatic Improvement After HoLEP
The goal of this observational study is to determine whether the rate of prostate tissue removed during surgery relative to the preoperative total prostate volume (referred to as the "enucleation ratio") predicts symptomatic…
- Trial name
- NCT07591688
- Testing
- Holmium laser enucleation of prostate (HoLEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ondokuz Mayıs University
Lower Urinary Tract Symptoms, Lower Urinary Tract Obstructive Syndrome
EEP in Patients With Urodynamically Proven DU/DA
The aim of this project is to create und evaluate a multicentral, retro-/prospective database for patients with urodynamically proven detrusor underactivity (DU) or acontractility (DA) secondary to a non-neurogenic aetiology, who…
- Conditions
- Lower Urinary Tract Symptoms, Lower Urinary Tract Obstructive Syndrome, Detrusor Underactivity, Detrusor Areflexia
- Trial name
- NCT06452927
- Testing
- Endoscopic enucleation of the prostate
- Volunteers
- 300 people
- Sponsor
- EEPiDuDa Study Group
Benign Prostatic Hyperplasia
Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life.
- Trial name
- HoLEP and TURP (NCT07663097)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Transurethral Resection of the Prostate (TURP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Benign Prostate Hypertrophy(BPH)
Orientation Video Training Administered at Different Times to Patients Undergoing Prostate Surgery on Postoperative Pain and Anxiety (Video Training)
This study aims to evaluate the effect of operating room orientation video education delivered at different time points on postoperative pain and state anxiety in patients undergoing surgery for benign prostatic hyperplasia.
- Trial name
- NCT07778355
- Testing
- Operating Room Orientation Video Education, Routine Preoperative Information
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Ondokuz Mayıs University