Clinical trials: Hoarseness of Voice
Dysphagia, Dysphonia
Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)
This study examines the presence, severity and natural history of dysphagia and dysphonia in the post-extubation and severely unwell COVID-19 patient.
- Conditions
- Dysphagia, Dysphonia, Subglottic Stenosis, Voice Disorders
- Trial name
- DYADS (NCT04584658)
- Testing
- Fibreoptic Endoscopic Evaluation of Swallowing (FEES), Videofluoroscopy, Dysphagia Handicap Index (DHI)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Spasmodic Dysphonia
EMG-Guided Versus Endoscopic-Catheter Botulinum Toxin Injection for Spasmodic Dysphonia
This randomized, controlled non-inferiority trial will compare two established botulinum toxin injection techniques for adductor spasmodic dysphonia: percutaneous electromyography-guided injection and transnasal endoscopic…
- Trial name
- NCT07894172
- Testing
- Intervention A - Electromyography (EMG)-Guided BTX Injection, Intervention B - Endoscopic Catheter BTX Injection
- Volunteers
- 17 people
- Sponsor
- Chinese University of Hong Kong
Vocal Cord; Injury, Superficial
Laryngeal Injuries After Removal of the Tracheal Tube: A Comparison Between Sevoflurane and Propofol
Vocal cord injuries occur not only during tracheal intubation, but also during surgery and during removal of tracheal tube. Volatile anesthetics increase neuromuscular block of muscle relaxants.
- Trial name
- NCT01616966
- Testing
- Sevoflurane, propofol
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University of Rostock
Laryngeal Dystonia, Focal Dystonia
Effects of Neuromodulation in Laryngeal Dystonia
Laryngeal dystonia (LD) causes excessive vocal fold abduction (opening) or adduction (closing) leading to decreased voice quality, job prospects, self-worth and quality of life.
- Trial name
- NCT05095740
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Vocal Fold Nodules, Muscle Tension Dysphonia
Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback
Patients with vocal hyperfunction will undergo standard of care voice therapy with ambulatory voice monitoring before therapy and after the first 3 voice therapy sessions.
- Trial name
- NCT03416868
- Testing
- Ambulatory voice biofeedback
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Massachusetts General Hospital
Voice Disorders, Muscle Tension Dysphonia
RCT Face-to-face Group Voice Therapy vs Telepractice Group Voice Therapy for Muscle Tension Dysphonia
The goal of this clinical trial is to compare face-to-face group voice therapy to telepractice group voice therapy for muscle tension dysphonia (MTD).
- Conditions
- Voice Disorders, Muscle Tension Dysphonia, Aphonia
- Trial name
- NCT06524193
- Testing
- Telepractice group voice therapy, Face-to-face group voice therapy
- Where
- Hong Kong
- Volunteers
- 168 people
- Sponsor
- Chinese University of Hong Kong
Hoarseness, Intubation
Rigid Video Stylet Vs Conventional Lightwand Intubation
Lightwand is a useful alternative device for intubation but scooping movement can induce damage and microbleeding of oral mucosa, postoperative hoarseness,sore throat.
- Conditions
- Hoarseness, Intubation, Sorethroat
- Trial name
- Optiscope (NCT02073786)
- Testing
- Conventional lightwand intubation, Rigid video stylet
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Dysphonia
Intensive Versus Traditional Voice Therapy
The purpose of this study is to determine if there are differences in treatment outcomes between traditional voice therapy, performed weekly for a maximum of 6 weeks versus intensive voice therapy, consisting of 4-6 therapy…
- Trial name
- NCT03129880
- Testing
- Weekly Voice Therapy, Intensive Voice Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Dysphonia
Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes
Despite the considerable use of oral steroids in the regular management of benign vocal fold lesions there is little evidence base in the literature.
- Trial name
- AAO (NCT02286960)
- Testing
- Steroid, Lactose Pills
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Respiration Disorders, Swallowing Disorder
Artificial Intelligence in Diagnosing Dysphagia Patients
In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device.
- Conditions
- Respiration Disorders, Swallowing Disorder, Phonation Disorder, Stroke
- Trial name
- NCT05098808
- Testing
- Acoustic features (from signals obtained during phonation)
- Where
- South Korea
- Volunteers
- 449 people
- Sponsor
- The Catholic University of Korea
Spasmodic Dysphonia, Laryngeal Dystonia
Examining the Spasmodic Dysphonia Diagnosis and Assessment Procedure (SD-DAP) for Measuring Symptom Change
This is a study of patients with spasmodic dysphonia to determine how best to measure the severity of the disorder in patients. It addresses which characteristics of speech are the best indicator of whether or not a particular…
- Trial name
- NCT02061943
- Where
- 2 sites in United States
- Sponsor
- Emory University
Spasmodic Dysphonia, Focal Dystonia
Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia
This study will examine how the brain controls speech in patients with spasmodic dysphonia, a voice disorder that involves involuntary spasms of muscles in the larynx (voice box), causing breaks in speech.
- Trial name
- NCT00713414
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Laryngeal Nerve Injuries, Thyroidectomy
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
The frequent occurrence of impaired function in the external branch of the superior laryngeal nerves following thyroid surgery is recognized as a prevalent complication leading to a diminished quality of life.
- Conditions
- Laryngeal Nerve Injuries, Thyroidectomy, Voice Change
- Trial name
- NCT06002984
- Testing
- Using Neuromonitoring to find EBSLN
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Voice Disorders in Children, Vocal Nodules in Children
Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules
The goal of this clinical trial is to determine and compare the effects of different voice therapy programs in children with vocal fold nodules.
- Conditions
- Voice Disorders in Children, Vocal Nodules in Children, Hoarseness, Dysphonia
- Trial name
- NCT05878197
- Testing
- Straw phonation, Resonant voice therapy, Vocal Hygiene
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Postoperative Complications, Postoperative Pain
Gender Specific Differences in Postoperative Sore Throat for Ambu® AuraGain™ Laryngeal Mask
The purpose of this study is to evaluate gender specific risk factors and the influence of cuff pressure in the occurrence of postoperative sore throat and hoarseness following general anaesthesia using Ambu® AuraGain™ Laryngeal…
- Trial name
- LadyLAMA (NCT04915534)
- Testing
- Ambu® AuraGain™ Laryngeal Mask (LM)
- Where
- Germany
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Secondary Hyperparathyroidism Due to Renal Causes
Pulmonary Function, Voice and Swallowing Symptoms After Parathyroidectomy
In this study, investigators measure patient's voice frequency, swallowing function, and O2 desaturation of the 6 mins walking test before surgery and 4 months after surgery, to find the increase of voice frequency, and…
- Trial name
- NCT04267965
- Testing
- parathyroidectomy plus bilateral thymectomy and autotransplantation
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Spasmodic Dysphonia, Laryngeal Dystonia
Extended-release Sodium Oxybate (Lumryz) in Spasmodic Dysphonia and Voice Tremor
Using a comprehensive approach of clinico-behavioral testing and neuroimaging, the researchers will examine the clinical effects of the extended-release formulation of sodium oxybate on voice symptoms in spasmodic dysphonia in an…
- Conditions
- Spasmodic Dysphonia, Laryngeal Dystonia, Voice Tremor
- Trial name
- NCT07041203
- Testing
- sodium oxybate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Kristina Simonyan
Functional Dysphonia
The Effects of Voice Therapy Based on the Estill Voice Model: a Feasibility Study
This study wants to investigate treatment for patients with common voice disorders where no surgical or medical treatment is needed. A voice disorder is when your voice is croaky, hoarse or when you lose it altogether.
- Trial name
- NCT02647840
- Testing
- voice therapy
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Postoperative Sore Throat, Bronchoscopy
Dexmedetomidine Nasal Spray and Postoperative Sore Throat After Bronchoscopy
The goal of this observational study is to learn whether dexmedetomidine nasal spray is associated with a lower risk of postoperative sore throat in adult patients who underwent bronchoscopy under general anesthesia.
- Conditions
- Postoperative Sore Throat, Bronchoscopy, Hoarseness, Dysphagia
- Trial name
- NCT07894224
- Testing
- Dexmedetomidine Nasal Spray, standard general anesthesia
- Where
- China
- Volunteers
- 4,400 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Dysphagia, Dysphonia
Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion
Our double-blinded, randomized control trial will assess the effect of nebulized racemic epinephrine inpatients undergoing anterior cervical discectomy and fusion (ACDF) procedures.
- Conditions
- Dysphagia, Dysphonia, Postoperative Pain
- Trial name
- NCT02724761
- Testing
- Racemic Epinephrine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Andrew Chung