Clinical trials: Hoarseness of Voice
Sore Throat
Effect of Intraoperative Neuromuscular Blockade on Postoperative Sore Throat and Hoarseness
Investigators assess and compare postoperative sore throat and hoarseness in the group using the muscle relaxant and not using it during the operation.
- Trial name
- NCT03397797
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- SMG-SNU Boramae Medical Center
Atrophy of Vocal Cord, Presbyphonia
PhoRTE® Therapy Efficacy: In-Person Versus Telehealth
This study compares how well voice therapy works when delivered in-person versus through telehealth for older adults with age-related voice problems.
- Conditions
- Atrophy of Vocal Cord, Presbyphonia, Dysphonia, Glottic Insufficiency
- Trial name
- NCT06934265
- Testing
- exuberant voice therapy
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Laryngopharyngeal Reflux, Cough
The Mechanism Versus PPI Trial
The goal of this clinical trial is to learn if a mechanism guided strategy that utilizes a multidisciplinary approach to treat adults patients (age 18-89) with chronic throat symptoms who are undergoing clinical evaluation for…
- Conditions
- Laryngopharyngeal Reflux, Cough, Throat Clearing, Dysphonia
- Trial name
- MVP (NCT06999577)
- Testing
- Omeprazole 40 MG, Laryngeal Recalibration Therapy, GERD Lifestyle Recommendations
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, San Diego
Dysphonia
Assessing the Effects of Patient Self-Rating of Voice Quality on Voice Therapy Attendance and Outcomes
The purpose of this study is to assess the effects of incorporating educational online modules into voice therapy. One of the main reasons that voice therapy fails is lack of participation and engagement from the patient's side.
- Trial name
- NCT05237648
- Testing
- Online Voice quality education module, Vocal hygiene module
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- NYU Langone Health
Transgender Women, Voice Alteration
Gender-affirming Voice Training With Visual Feedback
The goal of this clinical trial is to learn if prototype software can be used to train vocal pitch and resonance in trans women.
- Trial name
- NCT07017595
- Testing
- Visual-acoustic biofeedback: experimental
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Cincinnati
Vocal Cord Paralysis Unilateral, Dysphonia
Silk Protein Microparticle-based Filler for Injection Augmentation
This study will investigate the safety and efficacy of a silk protein microparticle-based filler for vocal fold injection augmentation to treat dysphonia/dysphagia secondary to vocal fold paralysis.
- Conditions
- Vocal Cord Paralysis Unilateral, Dysphonia, Dysphagia, Oropharyngeal
- Trial name
- NCT03790956
- Testing
- Silk Microparticle Filler Injection
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Southern California
Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients
Imaging Genetics of Laryngeal Dystonia
The contribution of genetic risk factors to the development of focal dystonias is evident. However, understanding of how variations in the causative gene expression lead to variations in brain abnormalities in different…
- Conditions
- Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients, Voice Tremor, Muscle Tension Dysphonia
- Trial name
- NCT03042975
- Testing
- MRI, Blood draw
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- Kristina Simonyan
Other Specified Injuries of Vocal Cord, Sequela
Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant)
Anesthesia induction and tracheal intubation can be performed with and without neuromuscular blocking agents (NMBAs). Tracheal intubation can be performed with sevoflurane instead of NMBAs; intubating conditions are similar and…
- Trial name
- SEVODosage (NCT01896245)
- Testing
- sevoflurane 1,0, sevoflurane 1,2, sevoflurane 1,4
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University of Rostock
Postoperative Sore Throat, Hoarseness
A Randomized, Comparative, Controlled Study of Differences in the Incidence of Postoperative Sore Throat (POST) by Inner Diameter Size of the TaperGuardTM Endotracheal Tube (ETT)
Postoperative sore throat (POST) is a common complication following general anesthesia involving endotracheal intubation, often leading to decreased patient satisfaction.
- Trial name
- NCT07511998
- Testing
- TaperGuard™ Endotracheal Tube
- Where
- South Korea
- Volunteers
- 246 people
- Sponsor
- Kyungpook National University Chilgok Hospital
Hoarseness, Dysphonia
A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring
The overall aim of the project is to develop a new method for treatment of untreatable severe hoarseness due to vocal fold scarring by local injection of autologous mesenchymal stromal cells (MSC).
- Conditions
- Hoarseness, Dysphonia, Aphonia, Vocal Fold Scar
- Trial name
- NCT04290182
- Testing
- MSC-KI-PL-204
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Karolinska University Hospital
Spasmodic Dysphonia, Voice Tremor
Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor
Using a comprehensive approach of clinico-behavioral testing, neuroimaging and pharmacogenetics, the researchers will examine the clinical effects of sodium oxybate and the matched placebo on voice symptoms in spasmodic dysphonia…
- Trial name
- NCT03292458
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Kristina Simonyan
Breast Cancer, Postoperative Sore Throat, Cough, Hoarseness
Hyaluronic Acid for Prevention of Post-Intubation Sore Throat and Hoarseness
The goal of this clinical trial is to find out whether applying Endotra Gel, a hyaluronic acid-based gel, to the endotracheal tube can help reduce sore throat and hoarseness after surgery.
- Conditions
- Breast Cancer, Postoperative Sore Throat, Cough, Hoarseness, Endotracheal Intubation, General Anesthesia
- Trial name
- NCT07040631
- Testing
- Endotra Gel
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Pusan National University Yangsan Hospital
Postoperative Sore Throat, Cough, Hoarseness
Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure
Endotracheal Tube (ETT) is frequently used for GA (general anesthesia) to deliver oxygen and volatile anesthetic agents to the patient and serves as a channel for anesthetic gases.
- Trial name
- NCT07315490
- Testing
- Xylocaine
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PAEC General Hospital, Islamabad