Clinical trials: Home Parenteral Nutrition
Malnutrition
Safety and Efficacy of Longterm HPN With Two Lipid Emulsions
It is the purpose of this trial to provide evidence for safety and efficacy of long term home parenteral nutrition with either Lipofundin MCT or Lipoplus in patients with proven insufficient enteral resorption.
- Trial name
- NCT00530738
- Testing
- Lipoplus, Lipofundin MCT
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- B. Braun Melsungen AG
Chronic Intestinal Failure
A Monocenter Prospective Study to Evaluate the Efficacy of Peripherally Inserted Central Catheter to Tunnelled Central Catheter With Cuff in Home Parenteral Nutrition for Long-term Used.
Home parenteral nutrition (HPN) is the reference treatment for anatomic or fonctionnal chronic intestinal failure. Nutritionnal catheter must follow two rules: low infection rate and be able to preserve the permeability of the…
- Trial name
- PICCNUT (NCT01840033)
- Testing
- group Piccnut, Tunnelled nutritional central catheter
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Home Parenteral Nutrition, Short Bowel Syndrome
SMOFLipid in Patients Who Are Intralipid Intolerant
Soybean oil based IV fat emulsion (IVFE) has been one of the sole sources of IVFE in the US. Soybean oil based IVFE has higher ratio of omega-6 to omega-3 fatty acids and can be associated with a number of complications including…
- Trial name
- NCT03054948
- Testing
- SMOFLipid, Standard therapy
- Where
- United States
- Sponsor
- Mayo Clinic
Metastatic Gastric Cancer
Home Parenteral Nutrition for Malnourished Unresectable Stage IV Gastric Cancer
This survey is a single arm study to assess the effect of home parenteral nutrition on overall survival, cycles of salvage chemotherapy completed, side effects of salvage chemotherapy, quality of life, nutritional status…
- Trial name
- NCT03121807
- Testing
- Oliclinomel N4 Per bag 1.5 L, Oxaliplatin, 5Fluorouracil
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Feeding Patterns, Sleep
Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition
The purpose of this study is to determine whether advancing the timing of home parenteral nutrition from overnight to daytime regimens leads to improved glucose profiles and sleep quality, and other changes in plasma metabolic…
- Conditions
- Feeding Patterns, Sleep, Glucose Intolerance, Short Bowel Syndrome
- Trial name
- NCT04743960
- Testing
- Time-of-day of parenteral nutrition provision
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Home Parenteral Nutrition, Central Venous Catheter
Taurolidine Lock in Long Term Parenteral Nutrition
Taurolidine alone or in combination with citrate have been proposed for locking the catheter to reduce the number of catheter infections.
- Trial name
- NCT02009189
- Testing
- 2% Taurolidine Lock, 1.35% Taurolidine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Liver Diseases
Evaluation of OMEGAVEN 10%® (n-3 EFA Lipid Emulsion) in Home Parenteral Nutrition-associated Liver Disease
The objective of the study is to show that substitution of the usual lipid emulsion (Intralipid 20%®) at a dose between 0.5 and 1.0 g/kg/infusion of parenteral nutrition (n-6:n-3 ratio = 7:1) by an equivalent dose of 0.5 to 1…
- Trial name
- MEGANORM (NCT01284049)
- Testing
- Intralipid 20%®, OMEGAVEN 10%®
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Home Parenteral Nutrition
Survey of Lifestyle and Its Feelings in Families of Patients in Home Parenteral Nutrition
Description of the life style of patients and families during the course of long term HPN. 1. Evaluation of the familial impact of HPN, and the way it is perceived 2.
- Trial name
- NPAD (NCT05048030)
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Imagine Institute
Outpatient Parenteral Antibiotic Therapy
Mobile-health Approach to Gather Clinical Information From Patients Following Hospital Discharge
The purpose of this study is to assess the feasibility of using a mobile-health approach to gather clinical data from patients following discharge from the hospital on outpatient parenteral antibiotic therapy (OPAT).
- Trial name
- NCT04709939
- Testing
- OPAT, Focus Group
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Iowa
Vascular Access Complication
Complications Related to Vascular Access Devices in Home Parenteral Nutrition Patients
Central vascular access devices are required for home parenteral nutrition (HPN). There is few data available concerning their complications in adult HPN patients, and the potential link between venous thromboembolism and…
- Trial name
- CRVADHPNP (NCT05948514)
- Testing
- The complications related to central venous access device
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Parenteral Nutrition, Infection
The AOT (Acridine Orange and Taurolidine) Trial
Total parenteral (intravenous) nutrition in the home setting (Home TPN or HPN) is a life saving strategy in patients who suffer from severe intestinal failure.
- Conditions
- Parenteral Nutrition, Infection, Sepsis
- Trial name
- NCT00321165
- Testing
- taurolidine
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Short Bowel Syndrome
Characterization of the Long-term Safety, Efficacy, and Pharmacodynamics Revestive® in the Management of Short Bowel Syndrome Pediatric Patients
The purpose of this study is to evaluate if the treatment could maximize intestinal absorption, minimize the inconvenience of diarrhea, and avoid, reduce or eliminate the need for parenteral support (PS) to achieve normal growth…
- Trial name
- REVE (NCT03562130)
- Testing
- Teduglutide
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intestinal Failure
Essential Fatty Acid Status & Immune Function in Parenteral Nutrition Patients
The purpose of this study is to determine if patients on long-term olive oil-based parenteral nutrition have an adequate essential fatty acid status and immune status, compared to age- and sex-matched healthy controls.
- Trial name
- NCT01986153
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Geert Wanten
Short Bowel Syndrome
Exenatide on GI Motor Function and Permeability in Short Bowel Syndrome
We plan to examine the gastrointestinal (GI) physiologic profile of Exenatide, a glucagon-like peptide (GLP-1) analog as a possible intestino-trophic growth factor capable of inducing small bowel adaptation and regeneration in…
- Trial name
- NCT01818648
- Testing
- Exenatide
- Sponsor
- Mayo Clinic
Advanced Cancer
Caregiver Assessments of the Quality of Home Hospice Care
The Objectives are to administer the Family Evaluation of Hospice Care (FEHC) questionnaire and The Texas Revised Inventory of Grief (TRIG) to caregivers previously enrolled into the parent grant and conduct supplemental analyses…
- Trial name
- NCT00895024
- Testing
- Phone Interview/Questionnaire
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Parenteral Nutrition, Home
Registry for Patients Receiving Intravenous Nutrition at Home
The purpose of study is to build a Canadian HTPN Registry to collect pertinent demographic and clinical data on the HTPN population in Canada and to determine the factors affecting survival, complications and TPN-dependency.
- Trial name
- HTPN (NCT02299466)
- Where
- 10 sites in Canada
- Volunteers
- 1,000 people
- Sponsor
- University Health Network, Toronto
Parenteral Nutrition
Longitudinal Evaluation of the Impact of Parenteral Nutrition
Patients with type 3 intestinal failure are completely reliant on artificial feeding and often manage this at home; home parenteral nutrition (HPN). HPN therapy is life saving for these patients.
- Trial name
- NCT04234490
- Testing
- Parenteral nutrition
- Where
- United Kingdom
- Volunteers
- 912 people
- Sponsor
- University of Manchester
Catheter-related Bloodstream Infection (CRBSI) Nos
Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
The purpose of the investigation is to compare two catheter lock solutions (TaurolockTMHep100 and Heparin 100 IE/ml), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a central…
- Trial name
- NCT01948245
- Testing
- TaurolockTMHep100, Heparin 100 IE/ml
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Palle Bekker Jeppesen
Home Parenteral Nutrition
Comparison of Two Intravenous Lipid Emulsions in Home Parenteral Nutrition Patients
Total Parenteral Nutrition (TPN) is a way of feeding a person intravenously, and is required when the gastrointestinal tract is not able to function properly. TPN contains carbohydrates, protein, and fat and lipids.
- Trial name
- NCT02796833
- Testing
- SMOFlipid20%
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Johane Allard
Cancer
Home Parenteral Nutrition in Cancer Patients
This study is being done to examine the effect of Parenteral (intravenous) nutrition support in the home setting on quality of life in cancer patients.
- Trial name
- NCT01152879
- Testing
- Home Parenteral Nutrition
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Southwestern Regional Medical Center