Clinical trials: Homologous Recombination Deficiency
Solid Tumor, Adult
Pembrolizumab Activity in Patients With Homologous Recombination Competent and Deficient Tumors
Phase II trial in which patients with metastatic solid tumors experiencing progression after first line standard chemotherapy or for which there is no standard chemotherapy, and for which pembrolizumab does not have an FDA or…
- Trial name
- NCT03274661
- Testing
- Pembrolizumab 200 mg Q3W
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Baptist Health South Florida
Metastatic Castration Resistant Prostate Cancer
A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib.
- Trial name
- TRITON2 (NCT02952534)
- Testing
- Rucaparib
- Where
- 149 sites in United States, Australia and 10 more
- Volunteers
- 277 people
- Sponsor
- pharmaand GmbH