Clinical trials: Hormonal Contraception
Contraception
Impact of Combined Hormonal Contraceptives on UPA
The purpose of this research study is to determine if taking a birth control pill effects how well an emergency contraceptive pill called Ulipristal acetate (UPA) works.
- Trial name
- NCT02577601
- Testing
- Ulipristal Acetate, Levonorgestrel (LNG)/Ethinyl estradiol birth control pill
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Nutrient Deficiency, Happiness
Alii Supplement Study
The goal of this clinical trial is to learn if the Alii Supplement can be used to reduce symptoms related to nutritional depletion in hormonal birth control pill users.
- Conditions
- Nutrient Deficiency, Happiness, Digestive Health, Vulnerability to Disease
- Trial name
- NCT07271316
- Testing
- Alii Supplement
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Texas Christian University
Chlamydia Infection, Neisseriaceae Infection
Hormonal Contraception and Risk of Chlamydia and Gonorrhea
There are biological reasons to suspect that hormones may affect the risk of a woman becoming infected with a sexually transmitted disease.
- Trial name
- NCT00091728
- Testing
- Depo Medroxyprogesterone acetate, Combined oral contraceptives
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Cystic Fibrosis Exacerbations While on and Off Hormonal Contraception
Contraceptive Hormones and Women With Cystic Fibrosis
Primary Objective Our primary objective in this study is to evaluate satisfaction of hormonal contraception in this sample of women and to evaluate the impact that this hormonal contraceptive has on cystic fibrosis (CF) disease…
- Trial name
- NCT02144246
- Testing
- Non-hormonal period, Ortho-cyclen, Ethinyl estradiol/norgestimate, 0.035 mg/0.250 mg
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pennsylvania
Contraception
The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies
Hormonal birth control methods include birth control pills, patches, and vaginal rings; they are normally available only with a doctor's prescription.
- Trial name
- NCT00065871
- Testing
- Contraceptive Screening by Pharmacist, Contraceptive Prescribing by Pharmacist
- Where
- 5 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV Infections
Hormonal Birth Control and the Risk of Acquiring HIV
The purpose of this study is to find out whether hormonal birth control increases, decreases, or does not change the risk of women becoming infected with HIV.
- Trial name
- NCT00006324
- Testing
- Ethinyl estradiol/levonorgestrel, Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 6,360 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Perfusion, Contraception
The Effects of the Female Hormones on Cerebral Perfusion
Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the variations in cerebral perfusion and other…
- Conditions
- Cerebral Perfusion, Contraception, Menstrual Cycle
- Trial name
- NCT03299179
- Testing
- MRI scan, Physiological monitoring, Blood sample
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Ghent
Menstrual Cycle, Achilles Tendon
Effects of the Menstrual Cycle on Triceps Surae Properties in Women
The menstrual cycle is an important biological rhythm, whereby large cyclic fluctuations in endogenous sex hormones, such as estrogen and progesterone, are observed, which can affect performance.
- Trial name
- NCT06214442
- Testing
- Evaluations of the mechanical properties of the achilles tendon in different phases of the menstrual cycle
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Marco Aurélio Vaz, PhD
Contraception
The Effect of Hormonal Contraceptives on Androgens and Glucose Metabolism
The impact of different administration routes of hormonal contraceptives on androgen secretion, glucose metabolism and inflammation. A prospective randomized trial.
- Trial name
- NCT01087879
- Testing
- Desogestrel-Ethinyl Estradiol contraceptive pill, Etonogestrel-Ethinyl Estradiol vaginal ring, Norelgestromin-Ethinyl Estradiol contraceptive patch
- Where
- Finland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Female Sexual Dysfunction, Polycystic Ovary Syndrome
Evaluation of Vitamin D in Women With PCOS and Sexual Dysfunction
SUMMARY: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive age women with a prevalence as high as 15%.
- Trial name
- Vit-D/PCOS (NCT02865187)
- Testing
- Vitamin D, Hormonal contraception
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Wright State University
Pain
Study of Pain Control With Hormonal IUS Insertion
This study aims to compare pain during insertion of the Skyla® IUS using a 100mm visual analog scale (VAS) among 92 young women aged 14 to 22 years randomized to receive a paracervical (n=46) block versus a sham paracervical…
- Trial name
- SOPHI (NCT02352714)
- Testing
- Paracervical Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Contraception
Pharmacists Expand Access to Reproductive heaLthcare
Prospective cohort study of women presenting to initiate hormonal contraception, prescribed by a clinician or pharmacist. Women will be followed for one year to assess contraceptive continuation and unintended pregnancy rates, as…
- Trial name
- PEARL (NCT03830567)
- Testing
- Pharmacist prescription, Clinician prescription
- Where
- United States
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Hormonal Contraception in Healthy Young Men (P42306)(COMPLETED)(P06057)
Male volunteers receive a new hormonal contraceptive consisting of an implant releasing a hormone and hormone injections in order to investigate the suppressive effect on sperm production and reversibility of sperm production…
- Trial name
- NCT00403793
- Testing
- etonogestrel with testosterone undecanoate
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
Nexplanon and Combined Oral Contraceptive (COC) Combined Use Study
Women currently using or starting a combined oral contraceptive will be offered study enrollment. Study subjects will have a Nexplanon placed and followed for 6 months to evaluate if they continue the COC, continue the implant…
- Trial name
- NexTOC (NCT02852265)
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Contraception, Estrogen Deficiency
Effect of Oestrogen on Musculoskeletal Outcomes
This cross-sectional comparison and prospective cohort design study will investigate differences in calcium metabolism, biochemical markers of bone and reproductive health, musculoskeletal health, and iron status between women…
- Conditions
- Contraception, Estrogen Deficiency, Estrogen Excess
- Trial name
- E2 (NCT05587920)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Army Health Branch, British Army
Women in Need of Long Acting Reversibel Cntraception With the Intrauterine Levonorgestrel Releasing System, Mirena
Pretreatment With Mifepristone Prior to Mirena Insertion
Hypothesis: Pretreatment with mifeprsitone prior to Mirena placement will induce amenorrhea and reduce bleeding irrregularities during the initial months of Mirena use.
- Trial name
- MiMi (NCT01931657)
- Testing
- Mifepristone prior to Mirena
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Ovulation, Luteal Development
The Effect of a Non-hormonal Cox-2 Inhibitor (Celebrex) on Ovulation
The purpose of this study is to assess the effect that Celebrex (a COX-2 inhibitor and non-steroidal anti-inflammatory drug) has on ovulation.
- Trial name
- NCT01129245
- Testing
- Celebrex
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Initiation of Oral Contraception (OC), Initiation of Depo-Provera (DMPA)
Modulation of Mucosal and Systemic Immunity by Hormonal Contraceptives
The investigators are conducting a research study to understand how cells responsible for fighting infection (immune cells) are affected by hormonal contraceptive use.
- Conditions
- Initiation of Oral Contraception (OC), Initiation of Depo-Provera (DMPA), Initiation of Mirena (LNG-IUD)
- Trial name
- NCT01750476
- Testing
- Mirena, Oral contraception, Depo-Provera
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Thomas Cherpes, DVM, MD
Contraception
Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles
To demonstrate the contraceptive efficacy of LF111 . To demonstrate the safety and tolerability of LF111 and assessment of pharmacokinetics of LF111.
- Trial name
- NCT02269241
- Testing
- LF111 (drospirenone)
- Where
- 37 sites in United States
- Volunteers
- 1,552 people, healthy volunteers welcome
- Sponsor
- Laboratories Leon Farma, S.A.