Clinical trials: Hormonal Contraception, open to volunteers
Energy Deficiency Due to Short-term Fasting, Hormonal Contraception
Energy Deficiency on Hormones in Contraceptive Users
The purpose of the present study is to characterize the endocrine and metabolic responses to a modest, short-term energy deficiency (~250 kcal/day) across the menstrual cycle in recreationally active women using different…
- Trial name
- NCT07651800
- Testing
- Energy Deficiency of approximately ~250 kcal/day
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Contraception Use
Sildosin as a Male Contraceptive Non Hormonal
In all, 200 healthy, sexually active, fertile male candidates will be assigned 100 in silodosin group and 100 in placebo group. Males using other contraceptive methods will be excluded.
- Trial name
- NCT07195097
- Testing
- Oral intake of sildosin
- Volunteers
- 200 people
- Sponsor
- Benha University
Female, Premenopausal
The Influence of Plan B® on Cardiovascular Health.
The goal of this double-blind randomized controlled trial is to learn about the impacts of a single dose of Plan B® on the cardiovascular system in young, health, premenopausal females.
- Trial name
- LEVOH (NCT07759635)
- Testing
- Plan B (Levonorgestrel)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University
Heavy Menstrual Bleeding, Bleeding Disorder
Hormonal Management of Heavy Menstrual Bleeding in Adolescents
The goal of this study is to evaluate whether hormonal medications (such as contraceptive pill, patch, injectable progestins and hormonal intra-uterine device) have similar efficacy at managing heavy menstrual bleeding in…
- Trial name
- JAdoRE (NCT06740929)
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- University Hospital, Geneva
Male Contraception
Open Label, Dose Escalation, Repeat Dose Study Evaluating YCT-529 in Healthy Males
This is a Phase 1b/2a open-label, dose escalation 3 part-study, 28-day, 90-day or 180 day repeat dose study of YCT-529 in healthy males who have decided to have a vasectomy and are waiting for the procedure and for men who have…
- Trial name
- NCT06542237
- Testing
- YCT-529
- Where
- New Zealand
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- YourChoice Therapeutics, Inc.
Eumenorrhea, Intrauterine Devices, Medicated
Effect of Different Sex Hormone Profiles for the Response to Physical Training
The aim of the project is to elucidate the impact of diverse sex hormone profiles on the adaptability of muscle mass to physical training.
- Conditions
- Eumenorrhea, Intrauterine Devices, Medicated, Hormonal Contraception
- Trial name
- NCT07115849
- Testing
- Physical training
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Menstrual Cycle, Hormonal Contraception
Oxytocin and Reward Processing in Women
Oxytocin is a hypothalamic neuropeptide that is best known for its peripheral physiological effects in the female organism i.e., uterine contractions during birth.
- Trial name
- NCT06222749
- Testing
- Intranasal oxytocin administration
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Contraception
Contraceptive Efficacy Study of Ovaprene
This will be a multi-center, single arm, open-label study of Ovaprene, a non-hormonal intravaginal ring, to investigate the contraceptive effectiveness, safety and acceptability of Ovaprene.
- Trial name
- NCT06127199
- Testing
- Ovaprene
- Where
- 27 sites in United States
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Contraception, Birth Control
Safety of a Contraceptive Copper Vaginal Ring
Many birth control options today come with unwanted side effects or risks. Hormonal methods can affect both mental and physical health, while devices like copper IUDs carry risks such as uterine perforation or infection.
- Conditions
- Contraception, Birth Control, Pregnancy Prevention
- Trial name
- NCT07666997
- Testing
- Vaginal Ring
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Elle, MD Biotechnologies Inc.
The Focus of the Study is to Investigate Reversible Effects of Combined Oral Contraceptive Use on Serotonergic Neurotransmission, Healthy Adult Females
Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission
The goal of this study is to learn about potential reversible effects of combined oral contraceptive (COC) use on the serotonergic brain system.
- Trial name
- REVERSE (NCT07511439)
- Testing
- Discontinuation of 2nd generation combined oral contraceptive use, Continuation of 2nd generation combined oral contraceptive use
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Male Contraception, Semen Volume
Effects of NLS-133, a Potential Non-Hormonal "On-Demand" Male Contraceptive
NLS-133-CLIN001 is a Phase 2a study designed to assess the safety, tolerability, and effects of NLS-133 (combination of two FDA-approved agents) compared to an active control (FDA-approved pharmacologic agent) or placebo on semen…
- Conditions
- Male Contraception, Semen Volume, Sperm Motility
- Trial name
- NCT07393334
- Testing
- NLS-133, Active Comparator #1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Menstruation Disturbances, Metrorrhagia
Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users
The goal of this clinical trial is to evaluate the effectiveness of transdermal contraceptive patches in treating irregular vaginal bleeding in women over 18 years old who are using contraceptive implants and experiencing…
- Conditions
- Menstruation Disturbances, Metrorrhagia, Uterine Hemorrhage, Contraception Behavior
- Trial name
- NCT07083635
- Testing
- Transdermal Ethinyl Estradiol/Norelgestromin Patch
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Chulalongkorn University
Contraception, Pharmaceutical Services
Hormonal Contraception Access Through Pharmacist Prescribing Implementation
The goal of this clinical trial is to learn if use of the HAPPI software can improve pharmacist-provided birth control services. The main questions it aims to answer are: 1.
- Conditions
- Contraception, Pharmaceutical Services, Access and Linkage to Healthcare, Technology Use
- Trial name
- HAPPI (NCT06823037)
- Testing
- HAPPI software
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- EMPOWERX INC
Hormonal Contraception
Quality of Life During Different Regimens of Combined Hormonal Contraceptives in Women of Reproductive Age
The aim of the present study is to investigate the psychosexual effects of combined hormonal contraception regimens, comparing them in terms of estrogen type and dosage, hormonal combination regimen and different routes of…
- Trial name
- NCT06918873
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Musculoskeletal Injury, Hypogonadism
Adaptions and Resiliency to Multi-Stressor OpeRations
Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits.
- Conditions
- Musculoskeletal Injury, Hypogonadism, Hormonal Contraception
- Trial name
- ARMOR (NCT06455969)
- Testing
- Goserelin 3.6 MG, Multi-Stressor Training, Testosterone gel (AndroGel 5g)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bradley Nindl
Cerebral Perfusion, Contraception
The Effects of the Female Hormones on Cerebral Perfusion
Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the variations in cerebral perfusion and other…
- Conditions
- Cerebral Perfusion, Contraception, Menstrual Cycle
- Trial name
- NCT03299179
- Testing
- MRI scan, Physiological monitoring, Blood sample
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Ghent