Clinical trials: Hospital Infection
Prosthetic Joint Infection
Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital
1. Setting of antibiogram in orthopedic department 2. Evaluate the production of biofilm in bacteria isolated from specimens phenotypically and genotypically.
- Trial name
- NCT05239312
- Testing
- Antimicrobial
- Volunteers
- 90 people
- Sponsor
- Assiut University
Malnutrition
Observational Study at the Influence of Malnutrition on Infections
The purpose of this trial is to determine whether nutritional status has an impact on nosocomial infections. Study population are patients undergoing early neurological rehabilitation.
- Trial name
- Malnutrition (NCT01243528)
- Testing
- Laboratory values
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Marion Mertl-Roetzer
Infection Prevention
Infection, Prevention and Control: A Multifaceted Approach to Preventing Hospital Acquired Infections Principal
Decreasing infections that occur when a person is hospitalized requires effective infection prevention and control (IPAC) practices.
- Trial name
- NCT07083024
- Testing
- infection control education
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Queen's University
Complicated Intra-Abdominal Infections, cIAIs, Hospital-acquired Pneumonia (HAP)
Real-World Effectiveness of Aztreonam-Avibactam Against MBL-Producing CRE
Why This Study is Needed Some bacterial infections have become resistant to common antibiotics, making them very difficult to treat. This is a growing and serious health problem.
- Conditions
- Complicated Intra-Abdominal Infections, cIAIs, Hospital-acquired Pneumonia (HAP), Ventilator-Associated Pneumonia (VAP)
- Trial name
- AWARE (NCT07268560)
- Testing
- Aztreonam-Avibactam
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Sir Run Run Shaw Hospital
Pneumonia, Pneumococcal, Hiv
Prevention of Missed Opportunities for HIV Diagnosis by Promoting HIV Testing of Patients With Pneumococcal Pneumonia at Nice University Hospital (PneumoVIH)
According to usual practices, HIV testing should be performed for each patient diagnosed for pneumococcal pneumonia. Unfortunately, in 2018, only 27% of patients were tested for HIV following pneumococcal pneumonia in Nice…
- Trial name
- PneumoVIH (NCT04909268)
- Testing
- HIV testing
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pneumonia
Accuracy of Clinical and Diagnostic Studies for Pneumonia in Children
Pneumonia continues to be a leading cause of death in children under five years of age worldwide. Many studies have evaluated clinical signs and symptoms that may predict pneumonia.
- Trial name
- NCT03630380
- Testing
- Clinical History, Physical Exam Findings, Laboratory Findings
- Where
- Nepal
- Volunteers
- 1,000 people
- Sponsor
- Patan Academy of Health Sciences
Bacterial Pneumonia
Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus
Study 0019 (NCT00124020) compares the safety and effectiveness of an investigational drug, telavancin, with vancomycin for the treatment of hospital-acquired pneumonia.
- Trial name
- ATTAIN2 (NCT00124020)
- Testing
- Telavancin, Vancomycin
- Where
- Israel
- Volunteers
- 771 people
- Sponsor
- Cumberland Pharmaceuticals
Sepsis, Neonatal Mortality
Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates
The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the impact of a multi-component chlorination intervention in health care…
- Conditions
- Sepsis, Neonatal Mortality, Antibiotic Resistant Infection, Enteric Infections
- Trial name
- CLEAN (NCT06824350)
- Testing
- chlorination for water disinfection and surface disinfection, infection prevention and control messaging
- Where
- 2 sites in United States, Kenya
- Volunteers
- 45,450 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Sepsis, Infections
Bacillus Cereus Invasive Infections in Preterm Neonates Hospitalized in French Hospitals
Background. Bacillus cereus group (Bc) comprises twenty-six closely related species of spore-forming environmental bacteria. Recently, increased sepsis and septic shock caused by Bc were reported in preterm neonates (PN), and the…
- Trial name
- NCT06973174
- Testing
- Premature neonates with invasive infection caused by Bacillus cereus
- Where
- 13 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Children,Hospitalized, Infusion
Implementation of an Infusion Management Scheme to Improve Patient Outcome in Tertiary Children's Hospitals
This study is a multi-center before-after trial design. The object is to observe whether the incidence of central line associated blood stream infection(CLABSI) will tend to descend compared with retrospective electronic medical…
- Conditions
- Children,Hospitalized, Infusion, Infections
- Trial name
- NCT05152446
- Testing
- Infusion management scheme
- Where
- 9 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Children's Hospital of Fudan University
Group B Streptococcus Carrier in Childbirth, Group B Streptococcal Infection, Late-Onset
Serosurveillance Study of Maternally Derived Anti-GBS Antibody
Globally, neonatal mortality remains unacceptably high, with little change in the death rate in the first 28 days of life since 1990, despite reductions in under-5 mortality of up to 50% over the same period.
- Conditions
- Group B Streptococcus Carrier in Childbirth, Group B Streptococcal Infection, Late-Onset, Group B Streptococcal Infection, Early-Onset, Group B Streptococcus Neonatal Sepsis
- Trial name
- ProGreSs (NCT04549220)
- Where
- Uganda
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Hepatitis E
HEV in Patients With Acute Non-A, Non-B, Non-C Hepatitis in Al-Rajhy University Hospital for Liver
Hepatitis E is the fifth known human viral hepatitis and is probably the most common cause of acute viral hepatitis in the world.
- Trial name
- NCT03488589
- Testing
- serum samples for HEV RNA PCR
- Volunteers
- 150 people
- Sponsor
- Mahmoud Abdel Rahman
Covid19, Liver Diseases
Silymarin in COVID-19 Patients Admitted to Hospital With Elevated Liver Enzymes
Of patients admitted to an internal medicine ward with internistic diagnosis/es together with COVID-19, substantial proportion has elevated liver enzymes.
- Trial name
- SILCOVINT-21 (NCT04816682)
- Testing
- Silymarin
- Where
- 2 sites in Slovakia
- Volunteers
- 30 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Influenza, Acute Respiratory Infection
Surveillance of Influenza in Paediatric Intensive Care Units in Bavaria
The purpose of the study is to assess the number of severe, laboratory-confirmed influenza in children hospitalized to paediatric intensive care units.
- Trial name
- NCT01286285
- Where
- Germany
- Volunteers
- 1,140 people
- Sponsor
- University Children's Hospital, Wuerzburg
Prosthesis Related Infection
Contribution of the Sonication of Implants to the Diagnosis of Joint Prosthesis Infection: A Retrospective Cohort Study
Studies on sonication suffer from a heterogeneity which makes their analysis complex, due to the absence of a gold standard allowing positive cases to be defined unequivocally.
- Trial name
- SonicHUS (NCT05867108)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19
COVID-19 Testing in Patients With Vascular Disorders
Background: To investigate the prevalence of SARS-CoV-2 infection in hospitalized patients with vascular disorders after implementing institutional and governmental safety measures.
- Trial name
- NCT04838093
- Testing
- PCR
- Where
- Austria
- Volunteers
- 2,243 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pneumonia, Ventilator-Associated, Hospital-acquired Pneumonia
Comprehensive Molecular Diagnosis and Management of Hospital- and Ventilator-associated Pneumonia in Norway
HVAPNOR consists of Three work packages: 1. Prospective observational study of Hospital (HAP) - and ventilator-Associated pneumonia (VAP) at 5 hospitals in Norway.
- Conditions
- Pneumonia, Ventilator-Associated, Hospital-acquired Pneumonia, Infectious Disease, Infection, Hospital
- Trial name
- HVAPNOR (NCT04381247)
- Testing
- Molecular diagnostics in HAP and VAP
- Where
- Norway
- Volunteers
- 550 people
- Sponsor
- Vestre Viken Hospital Trust
Influenza Vaccine, Cost-Effectiveness
Cost-effectiveness of the Influenza Vaccination
Background: In Bangladesh, seasonal influenza imposes considerable health and economic burden, particularly for those at high risk of severe disease.
- Conditions
- Influenza Vaccine, Cost-Effectiveness, Vaccination
- Trial name
- NCT05996549
- Testing
- Quadrivalent Influenza Vaccine
- Where
- Bangladesh
- Volunteers
- 2,567 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Contaminated Medical or Biological Substances, Environmental-Pollution-Related Condition
Potential Risk for Bacterial Contamination in Ventilator Systems
Background: Few studies have investigated the difference of bacterial contamination between conventional reused ventilator systems and disposable closed ventilator-suction systems.
- Trial name
- NCT03359148
- Testing
- Disposable ventilator system, Conventional reused ventilator system
- Volunteers
- 27 people
- Sponsor
- Chang Gung University
Sepsis
Long-term Assessment of Patients Treated in the ICU for Sepsis
This study is a prospective, observational cohort clinical registry designed to describe clinical and epidemiological characteristics and outcomes of adult patients hospitalized with sepsis.
- Trial name
- LAPTUS (NCT07502794)
- Testing
- Usual Care
- Where
- Brazil
- Volunteers
- 760 people
- Sponsor
- Hospital Israelita Albert Einstein