Clinical trials: Hospitalization in Acute Care
Stroke, Acute Stroke
Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)
The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an…
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- BESTCAREICTUS (NCT07627399)
- Testing
- BEST CARE ICTUS_HC BUNDLE
- Where
- 4 sites in Spain
- Volunteers
- 700 people
- Sponsor
- University of Malaga
LTC-to-hospital Transfer Decision-making
Evaluation of the STEP Intervention for Long-Term Care Residents Facing Hospital Transfer Decisions
This trial will evaluate whether the Supporting Transitions and Empowering Preferences (STEP) toolkit can improve decision-making about hospital transfers in long-term care residents and their substitute decision-makers and…
- Trial name
- STEP (NCT07153341)
- Testing
- STEP Decision Support Toolkit
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Bruyère Health Research Institute.
Community-acquired Pneumonia
A Phase 1b/2a Study of the Safety and Pharmacokinetics of Rhu-plasma Gelsolin in Hospitalized Subjects With CAP
A Phase 1b/2a, Double-blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Plasma gelsolin (rhu-pGSN) Added to Standard of Care in Subjects…
- Trial name
- NCT03466073
- Testing
- Recombinant Human Plasma Gelsolin
- Where
- 8 sites in Australia, Georgia
- Volunteers
- 33 people
- Sponsor
- BioAegis Therapeutics Inc.
Smoking, Acute Coronary Syndrome
Smoking Cessation for Patients With Acute Coronary Syndrome (ACS)
The aim of the present study is to assess if a personal care program of smokers hospitalised for acute coronary syndrome can change the smoking habits as compared with similar patients in conventional care program at 6 months.
- Trial name
- PATPAC (NCT00987597)
- Testing
- Technique of in-vivo exposure (cigarette) and mental image exposure (craving), conventional follow-up
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Renal Failure, Infection
Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial
The primary objective of the study is to demonstrate the efficacy of 60% ethanol lock solution in preventing major catheter related infections in critically ill patients.
- Trial name
- ELVIS (NCT00875069)
- Testing
- Ethanol
- Where
- France
- Volunteers
- 1,460 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Leukemia, Hematopoietic Stem Cell Transplantation (SCT)
Impact of Supportive Care on the Experience of Hospitalization of Patients Staying in the Protected Area of the Department of Blood Diseases
Patients with acute leukemia or received SCT are hospitalized in protected area, at least for 28 days. In this area, there is some rules like: controlled-visit, protective-clothing….so patient are in social and familial isolation…
- Conditions
- Acute Leukemia, Hematopoietic Stem Cell Transplantation (SCT), Aplasia
- Trial name
- ASTERIA (NCT03959007)
- Testing
- Aesthetic therapy sessions, Questionnaire
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Lille
Acute Heart Failure
Pharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure
The purpose of the study was to evaluate the safety, tolerability and pharmacokinetics of an intravenous infusion of serelaxin on top of standard of care therapy, in pediatric patients with acute heart failure (AHF)
- Trial name
- RELAX-PEDS-PK (NCT02151383)
- Testing
- Serelaxin
- Where
- 10 sites in United States, Germany and 2 more
- Volunteers
- 12 people
- Sponsor
- Novartis Pharmaceuticals
BPSD (Behavioral and Psycological Symptoms of Dementia)
Psychosocial Intervention for Behavioral Symptoms in Hospitalized Patients With Dementia or Delirium
Behavioral and psychological symptoms are common among older adults hospitalized with dementia or delirium and may include agitation, wandering, delusions, hallucinations, aggression, oppositional behavior, and sleep…
- Trial name
- ESSECOA (NCT07778329)
- Testing
- Sensory and General Stimulation With Caregiver Education, Standard Pharmacological Management
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Heart Failure
SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.
Evaluation of the efficacy, safety and and cost of home care versus conventional hospitalization care at 3-months in patients with worsening chronic heart failure.
- Trial name
- SAFE-HOME (NCT03156686)
- Testing
- HOME-based hospitalization
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- French Cardiology Society
Heart Failure Acute
Evaluation and Support Care Process Within the Care Pathway of Heart Failure Patients
Acute heart failure current management turns out to be a relative failure considering its elevated economical and human costs and the poor results obtained in terms of disease outcome.
- Trial name
- FIL-EAS (NCT04878263)
- Testing
- Conventional hospitalization, FIL-EAS ic care pathway
- Where
- 2 sites in France
- Volunteers
- 361 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Psychosis, Anxiety
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care
The goal of this pilot randomized controlled trial is to learn if adult patients with acute psychiatric conditions can receive hospital-level care at home. The main question it aims to answer is: 1.
- Conditions
- Psychosis, Anxiety, Depression, Behavioral and Psychiatric Symptoms of Dementia
- Trial name
- BHH (NCT07364825)
- Testing
- Behavioral Health Home Hospital
- Where
- 4 sites in United States
- Volunteers
- 41 people
- Sponsor
- Brigham and Women's Hospital
Trauma (Including Fractures)
Stress in Trauma Patients in Triage Categories 3-5
The aim of this study is to better understand what causes patients the most concern immediately after an injury. We would like to find out how stressed patients are and whether the main causes of stress are pain, fear regarding…
- Trial name
- NCT07811830
- Testing
- Questionnaire and Physical Exam
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- Gabriela Katharina Pomper
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Respiratory Complication
Lung Ultrasound for Physiotherapy in Hospitalized Patients With Respiratory Complications
This study aims to evaluate the relevance of using point-of-care lung ultrasound (LUS) in modifying the physiotherapist's treatment plan for patients hospitalized in a general ward.
- Trial name
- NCT06412081
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Heart Failure, Acute Decompensated Heart Failure
Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure
This will be a prospective, cluster-randomized, crossover, non-inferiority trial of 250 participants within 48 hours of an inpatient admission for heart failure or emergency department presentation for heart failure with plans…
- Trial name
- NCT07018297
- Testing
- Early Discharge with Lasix® ONYU (furosemide injection, for subcutaneous use) using SQIN-Infusor
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Texas Southwestern Medical Center
Hospitalization Rate, Mortality Rate
Efficacy of Multi-disciplinary Integrated Post-acute Care in Patients Admission for Heart Failure
Background: Clinical heart failure patients always suffering from (1) worsen symptoms such as decreased activity tolerance, end-to-end breathing and excessive body fluid volume; (2) high medical expenses results from…
- Conditions
- Hospitalization Rate, Mortality Rate, Functional Recovery, Left Ventricle Ejection Fraction
- Trial name
- NCT04638179
- Testing
- Not intervention.Use retrospective case contrl study.
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Mental Disorders, Cultural Competency
Adaptation Plan for Culturally Competent Care (PAACI) in the Acute Psychiatric Unit.
This observational study aims to design, implement, and evaluate the Adaptation Plan for Culturally Competent Care (PAACI) in the Acute Psychiatric Unit of Parc de Salut Mar, Barcelona.
- Conditions
- Mental Disorders, Cultural Competency, Psychiatric Hospitalization
- Trial name
- PAACI (NCT06879093)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Parc de Salut Mar
Psychotic Disorders
A Closed Unit Incorporating Soteria Elements Versus a Conventional Closed Psychiatric Ward
This prospective study compares two models of inpatient psychiatric care for adults experiencing an acute psychotic episode of moderate to severe intensity that requires admission to a closed psychiatric setting.
- Trial name
- CSCW (NCT07836348)
- Testing
- Inpatient Care in a Closed Unit Incorporating Soteria Elements, Conventional Closed Psychiatric Inpatient Care
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Jerusalem Mental Health Center
Readmission, Mental Health Disorder
Reducing Early Readmission to an Acute Psychiatric Unit
Early readmission to psychiatric units poses a significant challenge for both patients with mental health issues and healthcare institutions.
- Conditions
- Readmission, Mental Health Disorder, Hospitalizations Psychiatric
- Trial name
- PPREINGRESOS (NCT06604780)
- Testing
- Transitional discharge program
- Where
- Spain
- Volunteers
- 836 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Pulmonary Disease, Chronic Obstructive
Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this study is to compare the efficacy and safety of BCT197 when added on to standard of care in adult subjects with acute respiratory exacerbations of chronic obstructive pulmonary disease requiring…
- Trial name
- NCT02700919
- Testing
- BCT197
- Where
- 46 sites in United States, Bulgaria and 8 more
- Volunteers
- 282 people
- Sponsor
- Mereo BioPharma