Clinical trials: Host Disease Manifestation
Coronary Artery Disease, Percutaneous Coronary Intervention
Effect and Efficacy of Xpedition™/Alpine™, Everolimus-eluting Stent for Coronary Atherosclerosis
The objectives of this study are 1. To establish a prospective registry of the whole patients who received percutaneous coronary intervention with Xience Xpedition™/Alpine™ stent 2.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome, Angina Pectoris
- Trial name
- HOST-ALPINE (NCT02845804)
- Testing
- Alpine
- Where
- 20 sites in South Korea
- Volunteers
- 1,533 people
- Sponsor
- Seoul National University Hospital
Chronic Pain, Ventral Hernia
Chronic Complaints After Small Umbilical Hernia Repair
There are only little data on the risk of chronic complaints (pain and discomfort) following open non-mesh sutured repairs of small umbilical or epigastric hernias.
- Trial name
- NCT01741740
- Volunteers
- 295 people
- Sponsor
- Hvidovre University Hospital
Migraine
A Study of the Effectiveness and Safety of Topiramate Versus Placebo for Preventing Chronic Migraine Headaches
The purpose of this study is to assess the safety and effectiveness of topiramate as compared to placebo for the prevention of headaches in patients with chronic migraine.
- Trial name
- NCT00210912
- Testing
- topiramate
- Volunteers
- 328 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Migraine
Study of Efficacy and Safety of Erenumab in Adult Chronic Migraine Patients
The purpose of this study was to evaluate the efficacy and safety of erenumab in patients with chronic migraine in Asian population.
- Trial name
- DRAGON (NCT03867201)
- Testing
- Erenumab
- Where
- 63 sites in China, India and 7 more
- Volunteers
- 557 people
- Sponsor
- Novartis Pharmaceuticals
Burns, Knee Injuries
Opioid Laws and Pediatric Use
The legitimate need for opioid medications for acute pain management in pediatric trauma patients is recognized, however, the high dose and duration of opioid drugs prescribed by medical providers has been associated with an…
- Conditions
- Burns, Knee Injuries, Opioid Use, Pain
- Trial name
- NCT04543227
- Testing
- Opioid Use 90-Days Post Treatment
- Where
- United States
- Volunteers
- 980 people
- Sponsor
- Nationwide Children's Hospital
Chronic Low-back Pain
The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial
The goal of this randomized controlled trial is to compare lumbar interbody fusion surgery with multidisciplinary rehabilitation in participants aged 20-65 years with persisting (≥ one year) low back pain.
- Trial name
- LIFEHAB (NCT06169488)
- Testing
- Lumbar Interbody Fusion, Multidisciplinary rehabilitation
- Where
- 5 sites in Norway
- Volunteers
- 202 people
- Sponsor
- Oslo University Hospital
Cholecystitis, Acute, Cholecystitis, Chronic
Study of Pain Perception Between Males and Females Following Laparoscopic Cholecystectomy
This study looks at the differences in inflammatory mediators in gallbladder tissue between males and females and the possibility that these differences contribute to a higher perception of post-operative pain in females…
- Trial name
- NCT00575276
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Neck Pain
The Effects of Two Different Home-exercise Programmes on Women Suffering Long Term Neck/Shoulder Muscle Pain
The purpose of this study is to investigate the effects of specific neck/shoulder muscle exercises on pain, function, biochemistry and psychological factors in women suffering chronic neck/shoulder pain.
- Trial name
- NCT01876680
- Testing
- Stretching and aerobic exercise, Strength training
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Linkoeping University
Diabetic Neuropathic Pain, Chronic Low Back Pain
Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy
The purpose of the study is to determine whether the combination of the the three drugs gabapentin, duloxetine, and donepezil are effective in treating pain in people with diabetic neuropathy or patients with failed low back…
- Trial name
- NCT00619983
- Testing
- donepezil, duloxetine, donepezil 2.5 mg and duloxetine 30mg
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block
In adults with chronic low back pain, the investigators will compare the effectiveness of the medial bundle branch block on three lumbar levels (L3-L4, L4-L5 and L5-S1) performed either by radiographic guidance or by ultrasound…
- Trial name
- NCT04658953
- Testing
- Ultrasound guided infiltration, Fluoroscopy guided infiltration
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
Internet-delivered Behaviour Therapy for Children and Adolescents With Tourette's Disorder
The purpose of this trial is to evaluate the clinical efficacy, 12-month durability, and cost-effectiveness of BIP TIC - a therapist-guided and parent-guided internet-delivered behavioural intervention for children and…
- Trial name
- NCT03916055
- Testing
- Exposure and response prevention (ERP), Education on tics
- Where
- Sweden
- Volunteers
- 221 people
- Sponsor
- Karolinska Institutet
Low Back Pain
Duration of Spinal Manipulation Effects as Influenced by Orthotics
Purpose of study: To assess the effects of wearing custom orthotics as opposed to placebo foot inserts on the duration of chiropractic correction of spinal fixations and muscle imbalances using applied kinesiology techniques.
- Trial name
- NCT01704807
- Testing
- foot orthotics
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Logan College of Chiropractic
Low Back Pain, Chronic
Additional Effects of Retro Walking.
The aim of this study is to find the effects of retro walking along with core stabilization on pain, disability and balance in non-specific chronic low back pain patients.
- Trial name
- NCT07484542
- Testing
- Retro walking and Core stabilization, Core Stabilization
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Chronic Low-back Pain
Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments
The purpose of this study is to understand the mechanisms that underlie the beneficial effects of music-based treatments in individuals with moderate to severe chronic low back pain
- Trial name
- NCT05578781
- Testing
- Music Therapy, Music Medicine, Control group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
Immune Mediated Anemia, Immune Mediated Thrombocytopenia
Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias
Background: People who have a blood stem cell transplant can sometimes develop cytopenia. This means that their levels of one or more types of blood cell, such as the red cells or platelets, are lower than they should be.
- Conditions
- Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD
- Trial name
- NCT05509582
- Testing
- fostamatinib
- Where
- United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Low Back Pain
Placebo In Chronic Back Pain (Phase 2)
This study is designed to examine brain properties for placebo response in chronic back pain patients. The investigators have preliminary data indicating that, in blinded clinical trial studies with neutral instructions regarding…
- Trial name
- PICP2 (NCT02986334)
- Testing
- Naproxen, Omeprazole
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Apkar Apkarian
Chronic Low Back Pain
Gait in Low Back Pain Patients After Spinal Mobilization
Introduction: patients with chronic back pain as a result of degenerated disc disease, besides pain also present with impaired gait.
- Trial name
- SpinMob (NCT02645123)
- Testing
- TENS, spinal mobilization, swedish type massage
- Volunteers
- 75 people
- Sponsor
- University of Ioannina
Low Back Pain, Mechanical, Biofeedback, Pain, Chronic
The Effectiveness of Two Different Feedbacks in Core Stabilization Education for Chronic Nonspecific Low Back Pain
Abstract. Insufficient motor control mechanism of transversus abdominus and multifidus muscles is the most important cause of the chronic nonspecific low back pain (CNLBP).
- Trial name
- NCT03099941
- Testing
- Biofeedback
- Volunteers
- 38 people
- Sponsor
- Istanbul University
Back Pain, Low
Effects of Mackenzie and Tailored Mat Exercises in Post-Menopausal Women With Low Back Pain
Group A will receive tailored mat exercises. Group B will receive Mckenzie exercises. A baseline treatment including moist hot pack and TENS will be given to both of these groups.
- Trial name
- NCT06750380
- Testing
- Tailored mat exercise program, McKenzie exercises
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Myofascial Low Back Pain
Dry Dynamic Cupping vs Instrument-Assisted Soft Tissue Mobilization for Chronic Myofascial Low Back Pain
This study aims to compare the effects of Dry Dynamic Cupping and Instrument-Assisted Soft Tissue Mobilization (IASTM) in patients with chronic myofascial low back pain.
- Trial name
- NCT07685340
- Testing
- Instrument Assisted Soft Tissue Mobilization (IASTM), dry cupping
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Ibadat International University, Islamabad