Clinical trials: Households
Tuberculosis
A Home-Based Approach to Tuberculosis Preventive Treatment Management
Background: Tuberculosis (TB), though preventable and curable, remains a major public health concern worldwide. While elimination of tuberculosis infection (TBI) is critical to TB elimination, TBI continues to represent a…
- Trial name
- NCT07479030
- Testing
- A home-based approach to TB preventive treatment management
- Where
- Ethiopia
- Volunteers
- 1,300 people
- Sponsor
- Dilla University
Scabies, Households
Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon
It is unclear whether individual treatment of scabies is similarly effective compared to household treatment. This study therefore compares these two treatment strategies with topical benzyl benzoate for treating scabies in…
- Trial name
- NCT04205669
- Testing
- Benzyl Benzoate 25% Topical Application Lotion
- Where
- Gabon
- Volunteers
- 104 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Obesity
Does Obesity Influence Women Cardiorespiratory Fitness and Daily Physical Activities? (ACTIVOB)
Many obese individuals experience difficulties in executing household activities. In this study, we investigate the cardiorespiratory fitness (CRF) of obese vs.
- Trial name
- ACTIVOB (NCT03233061)
- Testing
- cardiorespiratory fitness and daily physical activities evaluations
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Laboratory of Movement, Condorcet, Tournai, Belgium
Influenza Prevention
Study to Assess the Prophylactic Efficacy and Safety of Sebaloxavir Marboxil Tablets/Oral Suspension for Influenza Prevention in Household Contacts Aged ≥2 Years.
This study is a randomized, double-blind, placebo-controlled phase III clinical trial. The trial participants include index participants (IP) and household contacts (HHC).
- Trial name
- NCT07730346
- Testing
- Sebaloxavir marboxil
- Where
- China
- Volunteers
- 858 people, healthy volunteers welcome
- Sponsor
- Nanjing Zenshine Pharmaceuticals
Smoking, Smoking Cessation
Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
The goal of this clinical trial is to compare the reach and effectiveness of the Refer2Quit intervention for increasing tobacco use treatment and quit rates among household members who smoke versus a treatment as usual group.
- Conditions
- Smoking, Smoking Cessation, Second Hand Tobacco Smoke
- Trial name
- NCT06582693
- Testing
- Refer2Quit
- Where
- United States
- Volunteers
- 3,200 people
- Sponsor
- Children's Hospital of Philadelphia
Tuberculosis, Multidrug-Resistant
Hotspots, Households and Hospitals: Enhanced Drug-resistant Tuberculosis Case Finding in Namibia
Poor case management, pharmacokinetic variability and on-going transmission have fostered the drug-resistant tuberculosis (DR-TB) epidemic leading to a global estimated number of >500,000 new multidrug resistant (MDR) TB cases…
- Trial name
- H3TB (NCT05022238)
- Where
- Namibia
- Volunteers
- 2,100 people
- Sponsor
- University of Namibia
Staphylococcal Skin Infection, Abscess
Individualized vs. Household MRSA Decolonization
The purpose of this research study is to compare the effectiveness of commonly used decolonization treatments (application of mupirocin antibiotic ointment to the nose and bleach baths) when performed by individuals with a…
- Conditions
- Staphylococcal Skin Infection, Abscess, Furunculosis, Staphylococcus Aureus
- Trial name
- HOME2DS (NCT01814371)
- Testing
- 2% mupirocin ointment, Bleach Bath (dilute), Hygiene Protocol
- Where
- United States
- Volunteers
- 474 people
- Sponsor
- Washington University School of Medicine
Food Insecurity
Feasibility of Online-supported Delivery Bringing Optimal Nutrition to Diverse Low-income Households With Children
The goal of this study is to find ways to help families with children who have limited incomes get better access to healthy and culturally appropriate foods.
- Trial name
- FOODBOX (NCT06870526)
- Testing
- Food box delivery
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Cornell University
Weight Loss
Weight Management Demonstration Project: HEALTH
The study investigated the effectiveness and cost-effectiveness of a cognitive and behavioral weight management program, complemented by an interactive Web site and brief telephone coaching, implemented among TRICARE…
- Trial name
- HEALTH (NCT01307280)
- Testing
- RCT1, RCT2, RCT3
- Where
- 3 sites in United States
- Volunteers
- 2,395 people
- Sponsor
- RTI International
COVID-19
COVID-19 Household Transmission Study
This study will test and follow persons quarantined at home after testing positive for SARS-CoV-2 (COV) aged 18 years and older and their household members aged 1 year and older.
- Trial name
- CO-HOST (NCT04445233)
- Testing
- COVID-19 IgM-IgG Rapid Test
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coronavirus Infection
COVID-19: Epidemiological Study of the Spread of SARS-CoV-2 in the Household of a Person Who Has Had a COVID-19 Disease
Evaluating the rate of exposure to the virus in the close contact population who shared the home of a person infected with SARS-CoV-2 at the time of infection of the index case - adults or children - is a major factor in…
- Trial name
- FAMICOV (NCT04511949)
- Testing
- COVID-19 IgG / IgM rapid test (whole blood, serum, plasma)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida
Influenza, Respiratory Viral Infection
Pilot of Cohort of Households for Influenza Monitoring and Evaluation in Seattle
This study will evaluate a home-based approach to influenza infection control, using prepositioned home-based influenza self-test kits, telemedicine services, and rapid delivery of Xofluza (Baloxavir marboxil) for administration…
- Trial name
- pCHIMES (NCT04141930)
- Testing
- Baloxavir Marboxil
- Where
- United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- University of Washington
Food Habits
Evaluating Household Food Behavior With a Smartphone App
The purpose of this study is to test the use of a smartphone app as a way to measure food waste. Investigators propose to improve the accuracy and convenience of household food waste measurement so that consumer food waste…
- Trial name
- FoodImage (NCT03309306)
- Testing
- Natural Environment/Stress Management, Natural Environment/Reduce Food Waste
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
COVID-19
Vitamin D for COVID-19 Trial
The Vitamin D for COVID-19 Trial (VIVID) is a randomized, placebo-controlled clinical trial in 2024 men and women from across the U.S. and Mongolia to investigate whether taking a daily dietary supplement of vitamin D vs.
- Trial name
- VIVID (NCT04536298)
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Diarrhoeal Disease, Hookworm Infection
Evaluating Impact of Improved Floors on Health
The goal of this intervention study is to learn about the impact of household flooring on health in rural Kenya, and test whether providing an improved (cement stabilised, washable) floor improves the health of children and their…
- Conditions
- Diarrhoeal Disease, Hookworm Infection, Ascaris Lumbricoides Infection, Trichuris Infection
- Trial name
- SABABU (NCT05914363)
- Testing
- Sealed washable floor plus behaviour change, Behaviour change intervention, Routine deworming
- Where
- Kenya
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Iron Deficiency Anemia
Effect of Nutrition Education on Vegetable and Legume Intake Among Households in Accra
The main purpose of this observational study is to determine the effect of nutrition education on the knowledge and behaviour of households towards the consumption of green leafy vegetables, legumes and vitamin C-rich fruits and…
- Trial name
- NCT07012473
- Testing
- Nutrition education on green leafy vegetables and legumes
- Where
- Ghana
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Ghana
Microbiome
Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19
The purpose of this study is to evaluate the effect of the probiotic Lactobacillus rhamnosus GG (LGG) and the effect of COVID-19 on the microbiome (the microorganisms that live in and on the human body) in exposed household…
- Trial name
- NCT04399252
- Testing
- Lactobacillus rhamnosus GG
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Duke University
Chronic Disease
Brief Interventions to Create Smoke-Free Home Policies in Low-Income Households: Texas Effectiveness Trial
The burden of tobacco use falls disproportionately on low-income populations, through high rates of primary smoking and exposure to secondhand smoke.
- Trial name
- SFH (NCT02097914)
- Testing
- Educational print materials and coaching call
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Food, Fortified, Dietary Habits
Acceptability of Fortified Bouillon Cubes in Northern Ghana
This study aims to evaluate the acceptability of bouillon cubes fortified with six micronutrients for which deficiency is common among women and children in Ghana and to assess the feasibility and reliability of data collection…
- Conditions
- Food, Fortified, Dietary Habits, Child Development
- Trial name
- NCT05177614
- Testing
- Upper-level multiple micronutrient-fortified bouillon cube, Lower-level multiple micronutrient-fortified bouillon cube, Iodine-fortified bouillon cube
- Where
- Ghana
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Tuberculosis Infection, Tuberculosis
BCG Revaccination in Children and Adolescents
Bacille Calmette Guerin (BCG) vaccine is one of the most used vaccines of the world, to reduce the risks of natural tuberculous infection.
- Trial name
- BRiC (NCT05330884)
- Testing
- BCG vaccine, Oral Chemoprophylaxis
- Where
- India
- Volunteers
- 9,200 people, healthy volunteers welcome
- Sponsor
- Tuberculosis Research Centre, India