Clinical trials: Human Immunodeficiency Virus Transmission
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Youth to Text or Telehealth for Engagement in HIV Care
Youth To Text or Telehealth for Engagement in HIV Care (Y2TEC) is a randomized control pilot to assess the feasibility and acceptability of delivering a targeted problem-solving intervention to youth ages 18-29 living with HIV…
- Conditions
- HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
- Trial name
- Y2TEC (NCT03681145)
- Testing
- Counselor delivered telehealth intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections
AIDS 347: IL-6 Blockade in Treated HIV Infection
The study is a phase I/II, double-blind, placebo-controlled, randomized cross-over clinical trial of tocilizumab (TCZ) or placebo in HIV-infected subjects receiving antiretroviral therapy with suppressed viral replication and…
- Trial name
- IL-6 (NCT02049437)
- Testing
- tocilizumab
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Case Western Reserve University
Hepatitis C, HIV Infections
Safety and Efficacy of Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Subjects Co-Infected With Hepatitis C Virus (HCV) and HIV
The purpose of this study is to determine whether the combination of telaprevir, peginterferon alfa-2a, and ribavirin is safe and effective in treating hepatitis C virus (HCV) infection in subjects who are infected with both HCV…
- Trial name
- NCT00983853
- Testing
- peginterferon alfa-2a, ribavirin (fixed dose), ribavirin (weight-based dose)
- Where
- 16 sites in United States, France and 2 more
- Volunteers
- 62 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
HIV/AIDS
Social Media HIV Prevention Intervention for High Risk Rural Women
The overall aim of this R34 application is to adapt and feasibility test an evidence-based HIV prevention education for high-risk, underserved rural women in Appalachia.
- Trial name
- NCT03456453
- Testing
- NIDA Standard for HIV Prevention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Michele Staton
Cytomegalovirus Retinitis, HIV Infections
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure
To examine the usefulness and safety of the antiviral drug foscarnet in treating AIDS patients with cytomegalovirus (CMV) infection that is causing sight-threatening inflammation of the retina in one or both eyes (CMV retinitis).
- Trial name
- NCT00000691
- Testing
- Foscarnet sodium
- Where
- 11 sites in United States
- Volunteers
- 156 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
HIV-1 Viral Dynamics in Subjects Initiating Raltegravir Therapy in Spain
The study purpose is to investigate plasma HIV-1 RNA dynamics in subjects initiating raltegravir-based salvage therapy and quantify the corresponding changes in levels of cellular HIV-1 DNA.
- Trial name
- NCT00685191
- Testing
- Salvage antiretroviral therapy including raltegravir
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Germans Trias i Pujol Hospital
HIV/AIDS
Community Health Worker And MHealth to ImProve Viral Suppression (CHAMPS Pilot)
The overall goal of this study is to evaluate the feasibility of a remotely delivered CHAMPS intervention for people living with HIV (PLWH) in a randomized controlled trial.
- Trial name
- CHAMPS Pilot (NCT05938413)
- Testing
- Wise App with medication adherence reminders, CHW Sessions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
HIV Infections, Neurologic Disorders
Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection
Background: HIV can sometimes cause HIV-associated neurocognitive disorder, or HAND. HAND is HIV-associated neurocognitive disorder. It can affect memory, thinking, or concentration. It can cause mood changes.
- Trial name
- NCT02527460
- Testing
- Anakinra
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
HIV - Human Immunodeficiency Virus
CD4 Cell Count at Antiretroviral Therapy Initiation or Re- Initiation
The primary purpose of this study is to assess the burden of advanced HIV disease (CD4 cell count <200 or <350 cells/μL) among new patients and those returning to care after a gap in treatment, and the extent to which low…
- Trial name
- CAIR (NCT07760324)
- Where
- Zambia
- Volunteers
- 151 people
- Sponsor
- Centre for Infectious Disease Research in Zambia
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia
To study the safety and effectiveness of trimetrexate (TMTX) plus leucovorin calcium rescue (LCV) in the treatment of Pneumocystis carinii pneumonia (PCP) in patients who have AIDS, patients who are HIV positive, or those for…
- Trial name
- NCT00000724
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Safety Study of Once a Day ART and Opiate Substitute.
This study looks at HIV-infected subjects who are on methadone treatment and medicines for HIV.
- Trial name
- 3OD (NCT00324688)
- Testing
- Viread
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Gilead Sciences
HIV Infections
Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers
The DaRifi study aims: 1. Develop adjusted doses of darunavir/ritonavir for use in HIV-infected patients requiring co-treatment of TB with a rifampicin-based regimen. 2.
- Trial name
- Darifi (NCT03892161)
- Testing
- Darunavir/ritonavir 800/100 mg tablet, Rifampicin 600mg QD tablet and DTG 50mg BD
- Where
- South Africa
- Volunteers
- 17 people
- Sponsor
- University of Cape Town
Hiv
Five Point Initiative: A Bundled Implementation Strategy to Address the HIV Epidemic in Black Communities
The purpose of this study is to assess the effectiveness of the FPI bundled implementation strategy in increasing HIV testing, Pre-exposure prophylaxis (PrEP) linkage (e.g., prescription) and knowledge, and condom use/access.
- Trial name
- FPI (NCT06062342)
- Testing
- FPI
- Where
- United States
- Volunteers
- 20,400 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV Infections
Evaluation of an HIV Outreach Program
This study evaluates outreach to HIV-infected people living in unstable housing in New York City who are new to CitiWide Harm Reduction.
- Trial name
- NCT00300183
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Montefiore Medical Center
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
MSM, HIV Infections
Risk Taking Behaviour in MSM and the Denial of Sexually Transmitted Diseases and HIV
Four focus groups , each of 10-15 males, ages 20-50 years old, MSM will be conducted by a medical sociologist. Two groups will be HIV negative participants and two groups of HIV positive MSM. Every group will meet for two hours.
- Conditions
- MSM, HIV Infections, Risky Behaviors
- Trial name
- MSM HIV (NCT01279005)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
HIV Infections, Neisseria Gonorrhoeae
Prevalence of Sexually Transmitted Infections (STIs) in HIV-infected Patients
There has been an increase in incidence in sexually transmitted infections in HIV infected patients in the last years. In this study the investigators will prospectively evaluate the prevalence of symptomatic and asymptomatic…
- Conditions
- HIV Infections, Neisseria Gonorrhoeae, Chlamydia Trachomatis, Herpes Simplex
- Trial name
- CTNG (NCT00973466)
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
HIV Seropositivity, HIV Drug Resistance
Study of the Prevalence of Transmitted HIV-1 Resistance, Viral Diversity, and Cluster Identification in Patients at the Time of HIV-1 Diagnosis
The primary objective of the study is to determine the frequency of transmission of viruses carrying at least one antiretroviral resistance mutation in all participants newly diagnosed with HIV-1
- Conditions
- HIV Seropositivity, HIV Drug Resistance, HIV Infections
- Trial name
- PRINAVIH (NCT07146529)
- Volunteers
- 30,060 people
- Sponsor
- ANRS, Emerging Infectious Diseases
CIN 2/3, HIV Infections
5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa
This is a single arm study on the safety, feasibility, and acceptability of adjuvant, self-administered, intravaginal 5-Fluorouracil (5-FU) following treatment for high-grade cervical precancer (CIN2/3) among women living with…
- Trial name
- NCT05362955
- Testing
- Intravaginal 5-Fluorouracil (5-FU)
- Where
- Kenya
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
HIV Infections, Hepatitis C
A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C Infection
This study evaluates patients infected with both HIV and Hepatitis C virus (HCV) who are receiving anti-HIV drugs. The purpose of this study is to learn more about HCV infection in patients whose HIV blood level decreases to less…
- Trial name
- NCT00001117
- Where
- 43 sites in United States, Puerto Rico
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.