Clinical trials: Human Immunodeficiency Virus Transmission
HIV Infections
A Test of Behavioral Intervention for Women at High Risk for HIV Infection
The purpose of this study is to find out if it is possible to conduct a group counseling program for women at risk for HIV infection. Women have been the fastest-growing group with new AIDS diagnoses.
- Trial name
- NCT00006440
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Influenza
Incidence of H1N1v Influenza-like Illness and Risk Factors for Serious Influenza Forms in HIV Infected Patients
To estimate the incidence of H1N1v influenza-like illness and to study the risk factors for serious influenza forms during pandemic period in French HIV infected patients.
- Trial name
- ANRS 2H (NCT01039220)
- Testing
- naso-pharyngeal swab
- Where
- France
- Volunteers
- 1,266 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
HIV-infection/AIDS
Vedolizumab Treatment in Antiretroviral Drug Treated Chronic HIV Infection
Background: In nearly all people with human immunodeficiency virus (HIV) infection, immunity cannot either control or eradicate the infection.
- Trial name
- HAVARTI (NCT03147859)
- Testing
- Vedolizumab (brand name Entyvio)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Ottawa Hospital Research Institute
HIV Infections
Neurocognitive Assessment in Youth Initiating HAART
ATN 071 is a prospective cohort study comparing neurocognitive functioning in four groups of youth, age 18-24: Two groups with CD4+ T cells above 350 cells/mm3 and HIV RNA >1,000 copies/ml, one initiating HAART (Group 1) and the…
- Trial name
- NCT00683579
- Testing
- Early Treatment with HAART, No treatment, HAART Treatment - standard care
- Where
- 21 sites in United States, Puerto Rico
- Volunteers
- 220 people
- Sponsor
- University of North Carolina, Chapel Hill
Acquired Immunodeficiency Syndrome, Blood Transfusion
Effectiveness of AIDS Antibody Screening
To determine the effectiveness of efforts to eliminate the human immunodeficiency virus (HIV) from whole blood and blood components in the blood supply.
- Conditions
- Acquired Immunodeficiency Syndrome, Blood Transfusion, HIV Infections
- Trial name
- NCT00005303
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV Infections, Sexually Transmitted Diseases, Bacterial
Mobile Enhanced Prevention Support for People Leaving Jail
This study will provide HIV prevention and related support services to men who have sex with men and transgender women who have substance use disorders and are either leaving jail or recently released from jail.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Bacterial, Hepatitis C, Substance Use Disorders
- Trial name
- MEPS (NCT04036396)
- Testing
- Mobile Enhanced Prevention Support, Usual Care plus Customized Referrals
- Where
- 3 sites in United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV Infections
Pharmacokinetics Safety and Acceptability of DRV/r for Children Living With HIV
The UNIVERSAL2 study is a research project designed to evaluate a newly developed formulation of an approved drug for children living with HIV aged over 3 years and weighing between 10 and 25 kg.
- Trial name
- UNIVERSAL2 (NCT06139796)
- Testing
- DRV/r FDC (120/20mg)
- Where
- 5 sites in Cameroon, Senegal and 2 more
- Sponsor
- PENTA Foundation
HIV Infections, Substance Use Disorders
Couples ART Adherence Intervention for PWID in Kazakhstan
The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression.
- Trial name
- NCT03555396
- Testing
- SMART Couples 2, Standard of Care
- Where
- Kazakhstan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
Meningitis, Cryptococcal, HIV Infections
A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.
To evaluate and estimate the safety and efficacy of the combination of fluconazole and flucytosine as treatment for acute cryptococcal meningitis in patients with AIDS.
- Trial name
- NCT00002113
- Testing
- Flucytosine, Fluconazole
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- Pfizer
HIV
Condom Performance in a Longitudinal Enhanced Assessment of User Experiences
This study will enroll 252 men who have sex with men (MSM) and 252 men who have sex with women (MSW) in a double-blind, three-way randomized crossover trial with conditions of fitted, thin, and standard condoms.
- Trial name
- C-PLEASURE (NCT02753842)
- Testing
- 5 Fitted Condoms, 5 Thin Condoms, 5 Standard Condoms
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Global Protection Corp.
HIV Seropositivity, Opioid-use Disorder
Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia
This pragmatic, multisite, implementation and effectiveness research evaluates a strategy to improve HIV treatment outcomes (increased rates of patients on ART with virological suppression, improved treatment retention and ART…
- Trial name
- NCT03987282
- Testing
- Enhanced usual care (EUC), Peer-based counseling
- Where
- Malaysia
- Volunteers
- 2 people
- Sponsor
- Yale University
HIV Infections, Hepatitis B
Hepatitis B Vaccination in HIV-infected Persons
In this study we compare the efficacy of two different HBV-vaccination schedules in HIV-infected persons concerning immune response and compliance. Short schedule: t=0,1,3 weeks and standard schedule: t=0,1,6 months.
- Trial name
- NCT00230061
- Testing
- HBVAXPRO, Hepatitis B (Recombinant) vaccine, 10 mcg/ml
- Where
- Netherlands
- Volunteers
- 800 people
- Sponsor
- Erasmus Medical Center
Sleep Wake Disorders, Sleep Initiation and Maintenance Disorders
AI-Powered Sleep Hygiene Mentor for Adults Living With HIV
Poor sleep is common among people living with HIV and is linked to fatigue, psychological distress and poorer adherence to antiretroviral therapy.
- Conditions
- Sleep Wake Disorders, Sleep Initiation and Maintenance Disorders, HIV Infections
- Trial name
- NCT07894042
- Testing
- AI-powered sleep hygiene mentor
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
HIV, Drug Use
Technology-Enhanced Peer Navigation to Improve IDUs' Engagement in HIV Care
The purpose of the mPeer2Peer Study (mP2P) is to see if we can use a smartphone and a Peer Navigator (PN) to improve medical care for HIV-positive people who have been out of HIV care for over one year.
- Trial name
- mP2P (NCT01941108)
- Testing
- Peer Navigation Arm
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV Infections, AIDS
Phase III PEG-Intron in HIV-infected Patients (Study P00738)
This is a randomized, double-blind, multicenter trial testing 2 doses of PEG-Intron, 1.0mcg/kg/week and 3.0mcg/kg/week in heavily treatment-experienced HIV-infected patients compared to placebo.
- Trial name
- NCT00035360
- Testing
- PEG-Intron
- Volunteers
- 49 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV (Human Immunodeficiency Virus), Pain
Auricular Point Acupressure for Pain
The goal of this pilot clinical trial is to learn whether auricular point acupressure (APA) can help reduce chronic musculoskeletal pain in adults age 50 and older who are living with HIV.
- Trial name
- NCT07852611
- Testing
- Auricular Point Acupressure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dan Song
HIV Seropositivity, CD4+ T Lymphocytopenia
Regional Differences in Human Immunodeficiency Virus (HIV) Testing
This retrospective observational study aims at the examination of regional differences in the procedure of referral for serological HIV testing between eastern (new) and western (old) German federal states.
- Trial name
- HIVRegional (NCT03158987)
- Testing
- Medical record review
- Where
- Germany
- Volunteers
- 999 people
- Sponsor
- Jena University Hospital
HIV Infections
Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008
A Phase I, Open-Label, Randomized, Crossover Trial to Investigate the Relative Bioavailability of the 25 mg Dapivirine Vaginal Ring-004 inserted every 30 days and 100 mg Dapivirine Vaginal Ring-008 inserted for 90 days in Healthy…
- Trial name
- NCT05416021
- Testing
- dapivirine
- Where
- South Africa
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
HIV Infections
A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Immuno-AG Recombinant HIV gp160 in Asymptomatic HIV Seropositive Individuals
To determine the safety and immunogenicity of vaccinia-derived HIV-1 recombinant envelope glycoprotein (gp160) in asymptomatic HIV-infected adult volunteers.
- Trial name
- NCT00000633
- Testing
- gp160 Vaccine (Immuno-AG), Hepatitis B Vaccine (Recombinant)
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection
Typology of Adherence in Adolescents: Phase II
A number of factors influence HIV-positive adolescents' acceptance of and willingness to continue taking anti-HIV medicines. These factors include mental health and substance abuse issues, barriers such as lack of medical…
- Trial name
- NCT00106678
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 1,200 people
- Sponsor
- University of North Carolina, Chapel Hill
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