Clinical trials: Human Immunodeficiency Viruses
HIV Infections, Tuberculosis
Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis
Raltegravir is a potent antiretroviral agent that could be used as an alternative to efavirenz in HIV-1 infected patients with tuberculosis.
- Trial name
- NCT00822315
- Testing
- efavirenz, raltegravir
- Where
- 9 sites in Brazil, France
- Volunteers
- 155 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections, Varicella-zoster Virus
The Immunogenicity of Varicella-zoster Virus Vaccine in HIV-infected Children
To study about the immunogenicity, safety and efficacy of varicella-zoster virus vaccine in HIV-infected children.
- Trial name
- NCT01138215
- Testing
- VZV vaccination
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
HIV Infections, AIDS
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Background: The incidence of lung cancer is quite high among people with the human immunodeficiency (HIV) virus. Frequent smoking may explain that cancer increase, given that 50% to 70% of HIV-infected people are current smokers.
- Conditions
- HIV Infections, AIDS, Lung Cancer, Tobacco Addiction
- Trial name
- NCT00491335
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
HIV, Substance-Related Disorders
Increasing MSM in the Continuum of Care in Kazakhstan
This study addresses the disproportionate representation of men who have sex with men (MSM) in the human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) pandemic in Kazakhstan, a country that has seen some…
- Trial name
- NCT02786615
- Testing
- Peer Unity
- Where
- 2 sites in United States, Kazakhstan
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Disease
Autonomic Neuropathy, GI Motility, and Inflammation in HIV
The purpose of this study is to explore a possible link between the autonomic nervous system and immune function in patients with HIV.
- Trial name
- ANGI (NCT02850276)
- Testing
- Pyridostigmine
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Infection, Human Immunodeficiency Virus
A Drug Interaction Study Evaluating GSK2248761 and Raltegravir Pharmacokinetics in Healthy Adult Subjects
In this study, approximately 16 subjects will receive raltegravir 400mg twice daily for 5 days (Treatment A) followed by a washout period. In Period 2, subjects will receive GSK2248761 200mg once daily for 5 days (Treatment B).
- Trial name
- NCT01101893
- Testing
- Raltegravir, GSK2248761, GSK2248761 + Raltegravir
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV Infection
Differences in Blood Levels of Nevirapine in HIV-infected Patients in Uganda and the United States
This study will determine whether blood levels of the anti-HIV medicine nevirapine are different in HIV-infected patients in the United States from patients in Uganda.
- Trial name
- NCT00054743
- Testing
- Blood draw
- Where
- 2 sites in United States, Uganda
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Infection, Human Immunodeficiency Virus
Effect of Rifampin (RIF) on the Pharmacokinetics (PK) of Oral Cabotegravir (CAB) in Healthy Subjects
CAB is an integrase inhibitor that is currently in Phase 2 clinical trials for the treatment and prevention of human immunodeficiency virus-1 (HIV-1) infection.
- Trial name
- NCT02411435
- Testing
- CAB, RIF
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV, Cardiovascular Disease
Men Together Making a Difference: Health Promotion for Black Men
African American men infected with HIV are living longer and are acquiring the same chronic non-communicable diseases affecting the general population of African American men age 40 years and older.
- Conditions
- HIV, Cardiovascular Disease, Diabetes, Hypertension
- Trial name
- NCT02572414
- Testing
- Health Promotion Intervention, Health Awareness Control Intervention
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- University of Pennsylvania
HIV Infections
Determination of HIV-1 Production by the Prostate
Virus present in semen likely contributes substantially to the sexual transmission of HIV. However, the source of HIV in semen is unknown.
- Trial name
- NCT00001584
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Cancer Institute (NCI)
HIV
Prevention of HIV Infection in High-Risk Social Networks of African American Men Who Have Sex With Men (MSM)
During the formative research phase, investigators will undertake formative studies to locate, understand, and characterize high-risk social networks of African American MSM in the community; gain community participation…
- Trial name
- C3 (NCT01825252)
- Testing
- Social Network Intervention, Counsel, Test, and Treat
- Where
- 2 sites in United States
- Volunteers
- 856 people
- Sponsor
- Medical College of Wisconsin
Hepatic Insufficiency
Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment
The primary objectives were: To determine the effects of steady state TPV co-administered with low dose RTV on steady state PegIFN and RBV in HIV negative subjects with mild hepatic impairment (scheme A) To determine the effects…
- Trial name
- NCT02259855
- Testing
- Tipranavir, Ritonavir, Pegylated interferon
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
HIV Infection
Observation of HIV-Infected Children Receiving Protease Inhibitor and Reverse Transcriptase Inhibitor
This study will continue to follow children who participated in an earlier National Cancer Institute trial of HIV treatment with a protease inhibitor.
- Trial name
- NCT00001826
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Acquired Immunodeficiency Syndrome
HIV Prevention Intervention for Couples
Recent studies have shown that many drug-using minority women are vulnerable to HIV infection from their husbands or other intimate male partners.
- Trial name
- NCT00325585
- Testing
- Couples HIV counseling and testing, Women's relationship-focused HIV counseling and testing
- Where
- United States
- Volunteers
- 780 people
- Sponsor
- National Development and Research Institutes, Inc.
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease
This study will examine the effectiveness of clofazimine in the prophylaxis of Mycobacterium avium complex infection in HIV infected individuals who are at risk to develop this untreatable opportunistic disease.
- Trial name
- NCT00002058
- Testing
- Clofazimine
- Where
- 2 sites in United States
- Sponsor
- University of California, San Francisco
Tuberculosis, Tuberculous Meningitis
Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)
The investigators will conduct a randomized, double blind, placebo controlled trial of adjunctive dexamethasone in the initial (6-8 weeks) treatment of tuberculous meningitis in Vietnamese adults.
- Conditions
- Tuberculosis, Tuberculous Meningitis, Drug-Induced Liver Injury, HIV
- Trial name
- NCT03092817
- Testing
- Dexamethasone
- Where
- 6 sites in Indonesia, Vietnam
- Volunteers
- 520 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Human Immunodeficiency Virus, AIDS
Relaxation Response With Acupuncture for HIV Patients
Advances in treatment has turned HIV/AIDS into a chronic illness. Relaxation response is a state in which individuals evoke a bodily calm, effecting physiological changes that are shown to be associated with improved immune…
- Trial name
- NCT00064740
- Testing
- relaxation response
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Health Care Quality, Access, and Evaluation, Delivery of Health Care
Improving HIV Screening With Nurse-Based Rapid Testing/Streamlined Counseling
Background: HIV testing is cost-effective in unselected general medical populations, yet testing rates among those at-risk remain low, even among those with regular primary care.
- Conditions
- Health Care Quality, Access, and Evaluation, Delivery of Health Care, Immune System Diseases, HIV Infections
- Trial name
- NCT00119548
- Testing
- Rates of HIV testing and receipt of results, Sexual risk reduction; HIV knowledge improvement
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
HIV Testing
Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care
Because adolescents and young adults face markedly increased HIV risk yet frequently do not test, we propose to complete the Mobile Augmented Screening (MAS) tool designed to increase HIV testing, and to facilitate linkage to…
- Trial name
- MAS (NCT03939455)
- Testing
- Mobile Augmented Screening tool
- Where
- United States
- Volunteers
- 295 people
- Sponsor
- New York University
HIV
Dyadic-Based Diagnosis, Care, and Prevention for HIV Discordant Couples in Tanzania
This is a prospective observational study of couples in Kisarawe, Tanzania who will be provided an intervention that offers: (1) HIV self-testing kits and pre-test counseling provided at the household, (2) linkage to a counseling…
- Trial name
- DDCP (NCT03098693)
- Testing
- HIV Self-Testing, Immediate Access to ART for HIV infected couple members, Access to PrEP for HIV uninfected couple members
- Where
- Tanzania
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.