Clinical trials: Human Papillomavirus (HPV)
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 4
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER4 (NCT05587738)
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- Monash University
Chlamydia Infections, Gonorrhea
Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections
Project FEDE-ITS will improve the STI knowledge and its treatment, of adolescents in the 1st and 2nd year of compulsory secondary education in the intervention group compared to compared to the control group, and will modify the…
- Conditions
- Chlamydia Infections, Gonorrhea, Syphilis Infection, Human Immunodeficiency Virus (HIV)
- Trial name
- FEDE-ITS (NCT05727033)
- Testing
- Participatory teaching group
- Where
- 4 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Human Papillomavirus Virus, HPV
Web App Technology for Boys and Parents: Improving HPV Vaccine Uptake
The uptake of vaccines for Human Papillomavirus (HPV) in the U.S. is far below recommended levels, particularly for adolescent boys and especially among minority families.
- Trial name
- NCT03000998
- Testing
- Web App Intervention Group, Usual Customary Care Group
- Where
- 3 sites in United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Human Immunodeficiency Virus, HPV Infection
Thermocoagulation for Treatment of Precancerous Cervical Lesions
The purpose of this study is to evaluate the safety, acceptability, and efficacy of Thermocoagulation for treatment of precancerous lesions among HIV-positive women in a screen-and-treat program in Western Kenya.
- Conditions
- Human Immunodeficiency Virus, HPV Infection, CIN 2/3
- Trial name
- NCT04191967
- Testing
- Thermocoagulation
- Where
- Kenya
- Volunteers
- 379 people
- Sponsor
- University of California, San Francisco
Human Papillomavirus (HPV)-Related Malignancies, Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies
Ribavirin for Patients With Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies
The purpose of this study is to find out the effects, both good and bad, that a drug called ribavirin has on the patient and the cancer.
- Trial name
- NCT02308241
- Testing
- Ribavirin
- Where
- 6 sites in United States
- Volunteers
- 12 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Solid Tumors, Adult, PIK3CA Mutation-Related Tumors
Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma
This phase I/II trial tests the safety, side effects, and best dose of alpelisib and whether alpelisib and carboplatin work to shrink tumors in patients with solid tumors or human papillomavirus (HPV) positive squamous cell…
- Conditions
- Solid Tumors, Adult, PIK3CA Mutation-Related Tumors, PIK3CA Mutation, Human Papillomavirus-Related Carcinoma
- Trial name
- NCT05472220
- Testing
- Alpelisib, Carboplatin, Hyperpolarized Carbon-13 (13C) Pyruvate
- Sponsor
- Pamela Munster
Oropharyngeal Squamous Cell Carcinoma (OPSCCA), HPV (Human Papillomavirus)-Associated
OPSCC N0 Nodal Control With Reduced IMRT
The dose of radiation most commonly used to treat oropharyngeal cancer results in side effects including sores in the mouth and throat, dry mouth and thick saliva, loss or altered taste, swallowing problems including pain or…
- Trial name
- NCT01891695
- Testing
- 39.6 Gy radiation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Paul W. Read, MD
HPV, Human Papillomavirus Viruses, Human Papilloma Virus Vaccine
SMS Reminders to Strengthen Demand for HPV Vaccination in Georgia
It is possible that achieving adequate HPV vaccination coverage will allow cervical cancer to be virtually eliminated. This is a priority for Georgia, where the burden of mortality and morbidity from cervical cancer is high and…
- Trial name
- NCT05536674
- Testing
- SMS reminder for the HPV vaccination
- Volunteers
- 55,176 people, healthy volunteers welcome
- Sponsor
- The Behavioural Insights Team
Human Papillomavirus (HPV), Head and Neck Squamous Cell Carcinoma (HNSCC)
RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC
The purpose of this research study is to determine the rate of local regional control at 2 years when using de-intensified chemoradiotherapy (CRT) in patients with Human Papillomavirus (HPV)-associated head and neck squamous cell…
- Trial name
- NCT04849377
- Testing
- RT 50 Gy, RT 54 GY, RT 60 GY
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV Infections, HPV - Anogenital Human Papilloma Virus Infection
Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women
Cervical cancer is the most common cause of cancer and a leading cause of death among HIV-infected women living in resource-limited settings.
- Trial name
- AIMA-CC (NCT03789513)
- Testing
- HPV test with partial genotyping and VIA triage
- Where
- 3 sites in Burkina Faso, Cambodia and 1 more
- Volunteers
- 3,000 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Human Papillomavirus, HPV-16
Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Background: Vulvar high-grade squamous intraepithelial lesion (HSIL) is caused by infection of the vulva with human papillomavirus (HPV). In a small percentage of cases, vulvar HSIL can turn into cancer.
- Conditions
- Human Papillomavirus, HPV-16, High Grade Squamous Intraepithelial Lesion
- Trial name
- NCT03197025
- Testing
- Aldesleukin, E6 T Cell Receptor (TCR)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Human Papillomavirus (HPV) Infection
Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (GSK580299) in Healthy Female Subjects 10-25 Years of Age.
Cervical cancer is the second most common cancer among women worldwide. Approximately 500 000 new cases are reported each year worldwide, from which 83% occur in developing countries.
- Trial name
- NCT00481767
- Testing
- Cervarix
- Where
- 2 sites in Senegal, Tanzania
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Papillomavirus (HPV)-Related Cervical Cancer, HPV DNA
Clinical Trial Comparing the Self-test for Cervicovaginal Sample Versus Samples From Service Provider (Xyto-Ro)
Problem Description When cervical cancer screening is needed, the Pap test (or Pap smears) is still the most common, although there are challenges that continue to prevent effective screening services in many countries, poor…
- Trial name
- Xyto-Ro (NCT04520464)
- Testing
- Cervical samples for identification of HR-HPV DNA via real-time PCTR.
- Where
- Mexico
- Volunteers
- 444 people
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Human Papillomavirus (HPV)
Multi-component Interventions to Increase HPV Vaccination in a Network of Pediatric Clinics
The purpose of the study is to determine the comparative effectiveness of a provider-only intervention and a parent plus provider intervention to increase initiation of HPV vaccination among male and female patients ages 11-17 in…
- Trial name
- NCT03111251
- Testing
- Provider assessment and feedback, Provider reminders, Provider education
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection
HPV Genotyping by DR. HPV Genotyping in Vitro Diagnostic Device (IVD) Kit in Exfoliated Cells of the Uterine Cervix
High-risk type human papillomavirus (HPV) is the known etiological agent of cervical cancer. HPV testing and risk stratification by genotyping has been recognized as an effective cervical screening program.
- Conditions
- Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection, HPV Infection
- Trial name
- NCT04333212
- Testing
- DR. Chip HPV genotyping IVD kit
- Where
- 4 sites in Taiwan
- Volunteers
- 1,103 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV)
New Strategies to Assess Anal Cancer Risk In Women
The purpose of this research is to study different strategies to identify women at highest risk for anal cancer. Primarily, investigators want to study a risk assessment called the Anal Cancer Risk Index; it gives women an…
- Trial name
- ANCAR-WIHS (NCT02873741)
- Testing
- Perianal and Digital Anorectal Exam, Cervical Swabs, Anal Swabs
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Emory University
Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma
Immunologic Responses in HPV-Associated Carcinoma for Patients Receiving Chemoradiation
The primary purpose of this research is to investigate anti-tumor immune responses in patients undergoing chemotherapy and radiation for Head and Neck Cancers.
- Conditions
- Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma, Oropharyngeal
- Trial name
- NCT01958515
- Testing
- research blood draw and tissue biopsy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Human Papillomavirus (HPV), Medically Assisted Procreation (MAP)
Prevalence of HPV Transmission During Medically Assisted Procreation Procedures
Human PapillomaVirus (HPV) are ones of the main causal agents of sexually transmitted diseases. Numerous HPV genotypes such as 16, 18, 31 or 45 are considered to be at high risk of oncogenicity especially for the anal and…
- Conditions
- Human Papillomavirus (HPV), Medically Assisted Procreation (MAP), Infertility
- Trial name
- AMPAMAVIR (NCT02524223)
- Testing
- Systematic HPV DNA assay in semen and cervicovaginal scrape, Systematic HPV DNA cervicovaginal scrape, systematic HPV Status in newborns in case of pregnancy
- Where
- 5 sites in France
- Volunteers
- 915 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Human Papillomavirus (HPV)
Fourth Dose of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + EP in Adult Females Previously Vaccinated With Three Doses of VGX-3100
DNA vaccines, which are small pieces of DNA also known as plasmids, have several advantages over traditional vaccines such as live attenuated virus and recombinant protein-based vaccines.
- Trial name
- NCT01188850
- Testing
- VGX-3100
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 14 people
- Sponsor
- Inovio Pharmaceuticals
Human Papillomavirus (HPV), Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
AMG 319 in HPV Positive and Negative HNSCC
The purpose of this study is to determine whether a drug called AMG 319 has an effect on a patient's own immune response to head and neck cancer squamous cell carcinoma (HNSCC).
- Trial name
- NCT02540928
- Testing
- AMG 319 hydrate
- Where
- 5 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Cancer Research UK