Clinical trials: Human Papillomavirus Virus
Human Papillomavirus Infection
A Comparison of Cotton and Flocked Swabs for Vaginal Self Collection
The purpose of this study is to compare the performance of cotton and flocked swabs for vaginal self-sampling.
- Trial name
- NCT02785289
- Testing
- Vaginal swab
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma
Immunologic Responses in HPV-Associated Carcinoma for Patients Receiving Chemoradiation
The primary purpose of this research is to investigate anti-tumor immune responses in patients undergoing chemotherapy and radiation for Head and Neck Cancers.
- Conditions
- Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma, Oropharyngeal
- Trial name
- NCT01958515
- Testing
- research blood draw and tissue biopsy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cervical Cancer
Human Papillomavirus Infection and Virus Genotyping in Uterine Cervix Cancer in Venezuela
1. Hypothesis: If high risk genotypes of human papillomavirus (HPV) is the cause of cervical cancer worldwide, the genotypes associated with cervical cancer in Venezuela would be the same types found in other countries. 2.
- Trial name
- HPI (NCT00937547)
- Where
- 2 sites in Venezuela
- Volunteers
- 329 people
- Sponsor
- Instituto Oncologico Luis Razetti
Infections, Papillomavirus
Safety and Immunogenicity Study of MEDI-517 (GSK 580299) With or Without Adjuvant in Healthy Adult Females
The goals of this study are to describe the safety, reactogenicity and immunogenicity of MEDI-517 with and without adjuvant in HPV-naïve humans. Long-term immune data is collected.
- Trial name
- NCT00693615
- Testing
- MEDI-517 HPV-16/18 VLP AS04 vaccine, MEDI-517 HPV-16/18 VLP vaccine with Al(OH)3, MEDI-517 HPV-16/18 VLP vaccine without adjuvant
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Recurrent Respiratory Papillomatosis
4-valent HPV Vaccine to Treat Recurrent Respiratory Papillomatosis in Children
Recurrent respiratory papillomatosis in children caused by HPV 6,11 can be a life threatening condition resulting in surgical interventions.
- Trial name
- NCT01995721
- Testing
- 4-valent HPV vaccine
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- National Institute of Child Health, Hungary
Human Papillomavirus Infection, Human Papillomavirus-Related Malignant Neoplasm
Extended Follow-up of Women Who Received One, Two, and Three Doses of the HPV Vaccine in the Costa Rica Vaccine Trial (CVT), ESCUDDO-CVT Study
This study is extending follow up of women who participated in the Costa Rica Vaccine Trial (CVT) and received one dose or two doses of the human papillomavirus (HPV) vaccine, along with a group of women who received three doses.
- Trial name
- NCT03309033
- Testing
- Biospecimen Collection, Questionnaire Administration
- Where
- Costa Rica
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Vulvar Intraepithelial Neoplasia Grade 2, Vulvar Intraepithelial Neoplasia Grade 3
Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)
This is a multicentre open labelled phase I trial evaluating the safety and preliminary efficacy of local decitabine treatment of human papillomavirus (HPV)-induced vulvar intraepithelial neoplasia (VIN) grade 2/3.
- Trial name
- DelVIN (NCT05717621)
- Testing
- VTD-101 ointment
- Where
- 5 sites in Germany
- Volunteers
- 29 people
- Sponsor
- ViMREX GmbH
HIV Infections
Study of Human Papillomavirus Related Genital Pathology Among HIV Positive Women
This study is a Multicentre cohort study with inclusion throughout the full duration of the study. The primary objective is the study of human papillomavirus related genital pathology in HIV positive women.
- Trial name
- ANRS CO17 (NCT01311752)
- Testing
- surgical management of high grade lesions
- Volunteers
- 676 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Human Papilloma Virus (HPV), High-risk Human Papillomavirus Infection
A Study of the Preliminary Efficacy of DARE-HPV to Treat High-risk Persistent Human Papillomavirus (hrHPV)
The goal of this clinical study is to learn if DARE-HPV can treat persistent high-risk human papillomavirus (hrHPV). The primary outcome will be if the genital infection clears following treatment in 30, 60 or 90 days.
- Trial name
- NCT07601074
- Testing
- Lopinavir / ritonavir
- Where
- 10 sites in United States
- Volunteers
- 118 people
- Sponsor
- Daré Bioscience, Inc.
Health Belief Model, Nursing Students
The Effect of Health Belief Model-Based HPV Infection and Vaccination Education on University Students' Knowledge and Health Beliefs
This study aimed to examine changes in knowledge and health beliefs (perceived susceptibility, severity, benefits, and barriers) regarding HPV infection and cervical cancer among students residing in a university dormitory…
- Conditions
- Health Belief Model, Nursing Students, HPV (Human Papillomavirus)-Associated
- Trial name
- NCT07900113
- Testing
- Educational intervention HPV
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Mersin University
Squamous Cell Carcinoma of the Oropharynx, HPV
Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients
Taking into account the excellent prognosis of patients with HPV-positive oropharyngeal cancer with < 10 pack-year smoking, the investigators hypothesize that reducing the intensity of therapy for these patients will reduce…
- Trial name
- NCT01663259
- Testing
- Cetuximab, Radiotherapy
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan Rogel Cancer Center
Papillomavirus Infections
Safety and Immunogenicity of Extended 2-dose Regimens of 9-valent Human Papillomavirus (9vHPV) Vaccine (V503-069)
This is a 96-month safety and immunogenicity study conducted in boys and girls 9 to 14 years of age and in young women 16 to 26 years of age.
- Trial name
- NCT04708041
- Testing
- 9vHPV vaccine
- Where
- 30 sites in United States, Colombia and 4 more
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
WHIM Syndrome
A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome
This natural history study is a prospective and retrospective, observational study of WHIM patients. WHIM syndrome is a rare, genetic, primary immunodeficiency disorder (a disorder in which the body's immune system does not…
- Trial name
- NCT03087370
- Testing
- No intervention
- Sponsor
- X4 Pharmaceuticals
Papillomavirus Infections, Dysplasia
Matrix Metalloproteinases and Human Papillomavirus in Dysplasias and Cancers of the Cervix
This study aims to compare the expression of matrix metalloproteinases and their tissue inhibitors between 4 groups of patients defined according to the severity of the cervical lesion.
- Conditions
- Papillomavirus Infections, Dysplasia, Cervix Cancer
- Trial name
- MMP-HPV (NCT04072913)
- Testing
- Vaginal samples (biopsies + vaginal smear)
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Bordeaux
Psoriasis
The Impact of Targeted Therapy on Microorganism in Patients With Psoriasis
Background: Psoriasis is a chronic, immunologically-mediated, inflammatory skin disease and targeted therapies e.g. tumor necrosis factor (TNF)-α and TH-17 antagonists have become increasing important agents in the management of…
- Trial name
- NCT01504113
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Human Papillomavirus DNA Tests, Cervical Cancer
IT-system Development for Reaching Cervix Cancer Screening Non-attenders
The main purpose is to develop and test an IT-infrastructure to provide more individualized ways of inviting and reaching women who have not participated, despite having been invited with annual reminders, in cervix cancer…
- Trial name
- NCT02750124
- Testing
- Cobas PCR Female swab sample Packet, Routine practice
- Volunteers
- 8,000 people
- Sponsor
- Karolinska Institutet
Human Papillomavirus (HPV)
Fourth Dose of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + EP in Adult Females Previously Vaccinated With Three Doses of VGX-3100
DNA vaccines, which are small pieces of DNA also known as plasmids, have several advantages over traditional vaccines such as live attenuated virus and recombinant protein-based vaccines.
- Trial name
- NCT01188850
- Testing
- VGX-3100
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 14 people
- Sponsor
- Inovio Pharmaceuticals
Human Papillomavirus
Study of Gardasil in Mid-Adult Males (MAM)
The purpose of this study is to test the effectiveness of the research study vaccine, Gardasil, in men ages 27-45 who have completed 4 years of observation in The Human Papillomavirus [HPV] infection in men (HIM) Study.
- Trial name
- NCT01432574
- Testing
- Gardasil
- Where
- 2 sites in United States, Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Human Papilloma Virus
Study of 2LPAPI® on the Clearance of Genital HR-HPV Infections.
Human papillomavirus (HPV) is a prevalent pathogen, the epidemiology of which has mostly been studied in the uterine cervix and the vagina.
- Trial name
- PAPION (NCT04232917)
- Testing
- 2LPAPI®
- Where
- 11 sites in Belgium, Romania
- Volunteers
- 284 people
- Sponsor
- Labo'Life
Cervical Cancer, Vulvar Cancer
Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
The study will evaluate the immunogenicity and safety of 4-valent and 9-valent HPV recombinant vaccine in Chinese healthy females 20 to 45 years of age.
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, CIN1
- Trial name
- NCT04425291
- Testing
- 4-valent HPV Vaccine, 9-valent HPV Vaccine, GARDASIL®
- Where
- China
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
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