Clinical trials: Human Papillomavirus Virus
Neoplasms, Rectal
A Post-marketing Surveillance Study to Assess the Safety of Cervarix (GlaxoSmithKline [GSK] Biologicals' Human Papillomavirus [HPV] -16/18 Vaccine), When Administered According to the Approved Prescribing Information (PI) in Korea
The purpose of this post-marketing surveillance (PMS) study is to collect safety information on the use of Cervarix upon the expanded indication to anal cancer to both women and men (at least 600 Korean women and men) within 30…
- Trial name
- NCT03671369
- Testing
- Safety data collection (following routine vaccination) by a continuous surveillance method.
- Where
- 29 sites in South Korea
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Papilloma Virus
A Dose Reduction Immunobridging and Safety Study of Two HPV Vaccines in Tanzanian Girls
Cervical cancer is the most common cancer in women aged 15-44 years in East Africa, and mortality rates are very high. HPV vaccines are most effective if given to girls who have not yet acquired HPV infection.
- Trial name
- DoRIS (NCT02834637)
- Testing
- bivalent HPV vaccine, nonavalent HPV vaccine
- Where
- Tanzania
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Human Papillomavirus Vaccine, Chronic Condition
Evaluation of Human Papillomavirus Vaccine Coverage in Girls and Young Women With Chronic Disease
The main objective of the study is to determine the vaccination coverage rate for human papillomavirus in adolescents aged 11 to 20 with chronic disease and treated at the Necker-Enfants Malades Hospital, compared to a population…
- Trial name
- MC-HPV (NCT06158802)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 223 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Human Papillomavirus-Related Carcinoma
A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer
This phase I/II trial studies how well PDS0101 alone or in combination with pembrolizumab works to shrink tumor in patients with human papillomavirus-associated oropharynx cancer that has spread to nearby tissue or lymph nodes…
- Conditions
- Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Human Papillomavirus-Related Carcinoma, Locally Advanced Oropharyngeal Carcinoma, Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
- Trial name
- NCT05232851
- Testing
- Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101, Pembrolizumab, Computed Tomography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Papilloma Viral Infection
HPV and Male Homosexuality in General Practice?
The main objective of this study is to find out whether young MSM (men who have sex with men) believe it is important for their GP to be informed of their sexual orientation, in order to improve their clinical, especially with…
- Trial name
- HPV (NCT05078554)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Anal Cancer, Neoplasm of Uncertain Malignant Potential
Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia
RATIONALE: Infrared coagulator ablation may be effective in preventing the development of anal cancer in patients with anal neoplasia PURPOSE: This randomized phase III trial is studying infrared coagulator ablation to see how…
- Conditions
- Anal Cancer, Neoplasm of Uncertain Malignant Potential, Nonneoplastic Condition, Precancerous Condition
- Trial name
- NCT01164722
- Testing
- clinical observation, infrared photocoagulation therapy
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- AIDS Malignancy Consortium
Human Papillomavirus (HPV) Infection
Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (GSK580299) in Healthy Female Subjects 10-25 Years of Age.
Cervical cancer is the second most common cancer among women worldwide. Approximately 500 000 new cases are reported each year worldwide, from which 83% occur in developing countries.
- Trial name
- NCT00481767
- Testing
- Cervarix
- Where
- 2 sites in Senegal, Tanzania
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Papilloma Virus
SDH of HPV Vaccine Completion
The purpose of this research study is to find out which factors influence parents' ability to complete the human papillomavirus (HPV) vaccine series for their child.
- Trial name
- NCT03709602
- Where
- United States
- Volunteers
- 3,076 people
- Sponsor
- Duke University
Oropharyngeal Squamous Cell Carcinoma
The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan
We will use the next-generation sequencing (NGS) technology to identify genomic alterations of Taiwanese HPV positive and negative oropharyngeal squamous cell carcinoma (OPSCC) for novel biomarker development and the study design…
- Trial name
- NCT05522881
- Where
- 7 sites in Taiwan
- Volunteers
- 410 people
- Sponsor
- National Health Research Institutes, Taiwan
Cervical Cancer
Immunotherapy of Recurrent Cervical Cancers Using Dendritic Cells (DCs)
Chemotherapy is the current standard treatment for unresectable recurrent cervical carcinoma after radiotherapy or distant metastasis of cervical carcinoma. The most effective regimens are cisplatin-based chemotherapy.
- Trial name
- NCT00155766
- Testing
- HPV16 E7 peptide-pulsed autologous DCs
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Oropharyngeal Squamous Cell Carcinoma (OPSCCA), HPV (Human Papillomavirus)-Associated
OPSCC N0 Nodal Control With Reduced IMRT
The dose of radiation most commonly used to treat oropharyngeal cancer results in side effects including sores in the mouth and throat, dry mouth and thick saliva, loss or altered taste, swallowing problems including pain or…
- Trial name
- NCT01891695
- Testing
- 39.6 Gy radiation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Paul W. Read, MD
Cervical Cancer Screening
Improving Cervical Cancer Screening in Women Living With HIV Attending Chronic Disease Clinics in Semi-rural Tanzania
This study is to analyse the effect of a bundle of measures on the proportion of females being screened for cervical cancer in the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO), comparing the time period before…
- Trial name
- NCT05256862
- Testing
- Data collection
- Where
- Tanzania
- Volunteers
- 2,974 people
- Sponsor
- University Hospital, Basel, Switzerland
Cervical Intraepithelial Neoplasia, Hysterectomy
Longitudinal HPV Pap in CIN and VAIN
This study will construct a longitudinal risk model of VaIN according to the HPVs distribution of cervix and vaginal for those had CIN2+.
- Conditions
- Cervical Intraepithelial Neoplasia, Hysterectomy, Human Papillomavirus, Vaginal Intraepithelial Neoplasia
- Trial name
- LHPCV (NCT05931354)
- Testing
- HPV test and Pap Smear
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Papillomavirus Infections
Natural History of Human Papillomavirus (HPV) Infections in Mid-Adult Women (WHIM)
The purpose of this study is to determine rates of oral and genital human papillomavirus (HPV) infections, and look at risk factors for HPV infection in healthy mid-adult women.
- Trial name
- WHIM (NCT01295242)
- Where
- United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- University of Washington
Papillomavirus Infections, HIV Infections
Oral Human Papillomavirus Infection in HIV-infected Men
Human papillomavirus (HPV)-infection belong to the most common sexually transmitted diseases worldwide. HIV-infected men having sex with men /MSM) are strongly associated with a higher prevalence of genitoanal HPV-infection, and…
- Trial name
- NCT00421486
- Testing
- Oral swabs for HPV-typing and high-risk HPV-determination
- Where
- 2 sites in Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Deutsche Luft und Raumfahrt
Vaccine Acceptance, Social Acceptance
Video to Promote HPV Vaccination
The purpose of this research study is to determine if video-based education will increase HPV vaccination rates among 11 - 17 year olds.
- Conditions
- Vaccine Acceptance, Social Acceptance, Acceptance Processes, Health Behavior
- Trial name
- NCT02196454
- Testing
- Educational Video with Male or Female Narrator
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Metastatic Anal Canal Cancer, Human Papillomavirus
Evaluation of Immune Response Against Human Papillomavirus (HPV)in Patients With Metastatic Cancer of the Anal Canal
Complete response is a rare event in metastatic anal cancer in the case of unresectable recurrence after radiochemotherapy. In the University Hospital Center of Besançon, 8 patients with metastatic anal cancer were treated…
- Trial name
- Epitopes-HPV01 (NCT01845779)
- Testing
- DCF regimen
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
HPV Infection, HPV-Related Carcinoma
To Evaluate the Safety and Immunogenicity of 15-valent HPV Recombinant Vaccine in Chinese People Aged 9-45 Years
To evaluate the safety and Immunogenicity of 15-valent HPV vaccine in 9-45year-old participants.
- Conditions
- HPV Infection, HPV-Related Carcinoma, HPV-Related Intraepithelial Neoplasia, Genital Wart
- Trial name
- NCT06756269
- Testing
- Medium dose for 15-HPV vaccine, High dose for 15-HPV vaccine, 9-HPV vaccine
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Aerodigestive Precancerous Lesions and Malignancies
Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies
This is a Phase I, open-label study to evaluate the safety, tolerability, and immunogenicity of INO-3106 alone or in combination with INO-9012 DNA vaccines delivered by Electroporation to subjects with HPV6 associated…
- Trial name
- NCT02241369
- Testing
- INO-3106, INO-9012
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Inovio Pharmaceuticals
Cervical Intraepithelial Neoplasia
A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age
The main purpose of this study was to evaluate the safety and reactogenicity of GlaxoSmithKline Biologicals SA (GSK)'s investigational adjuvanted human papillomavirus (HPV) vaccine formulations.
- Trial name
- NCT05496231
- Testing
- HPV9 High formulation, HPV9 Medium formulation, HPV9 Low formulation
- Where
- 68 sites in United States, Bulgaria and 6 more
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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