Clinical trials: Hunger
Hunger, Weight Change
Hunger Perception and Weight-Related Outcomes Following Use of a Leptin-Supporting Dietary Supplement
This study evaluates changes in hunger perception and body composition-related measures following daily use of a commercially available dietary supplement formulated to support leptin-related metabolic signaling.
- Trial name
- NCT07442864
- Testing
- Leptin Balance Formula
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Hunger
Study of Psyllium 6.8 g Versus Placebo on Satiety in Healthy Volunteers
This is a randomized, double-blind, placebo-controlled, 2-treatment, 3-period crossover design study to evaluate the effects of psyllium 6.8 g provided as sugarfree Metamucil fiber supplement powder dissolved in water versus…
- Trial name
- NCT01809925
- Testing
- psyllium fiber 6.8g
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Self Reported Ratings of Hunger
The Effects of Processed Whole Orange on Subjective Ratings of Satiety
The study is a human dietary test meal study that is a randomized, controlled, double blind, cross over design with 3 intervention arms that will investigate the subjective ratings of satiety in response to different levels of…
- Trial name
- POAS (NCT02116023)
- Testing
- Orange flavored beverage
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Diabetes Mellitus, Type 2, Obesity
Investigation Of Weight Loss And Body Composition Changes After Dosing With Either Placebo Or One Of Two Active Drugs
The drugs GSK189075 and GW869682 result in increased caloric losses. This study is investigating how if taken over 8 weeks that affects weight loss, food intake and the composition of the body.
- Trial name
- NCT00494767
- Testing
- GW869682, GSK189075
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Appetite
Pasta Formulations and Their Effect on Appetite
Investigators are interested in learning how appetite responds to pasta containing different amounts of protein and fiber. In this research study, subjects will be asked to eat as much as they want of pasta containing different…
- Trial name
- SAT (NCT01145963)
- Testing
- Control pasta, Experimental pasta B, Experimental pasta C
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Glycemic, Insulinemic
Glycemic and Insulinemic Impact of a Test Granola Versus a Control Granola
The objectives of this study are to examine the blood glucose and serum insulin response elicited by servings of Test Granola and Control Granola containing equal amounts of available carbohydrate over a 3 h time period.
- Conditions
- Glycemic, Insulinemic, Subjective Hunger Responses
- Trial name
- NCT03495778
- Testing
- Test Granola, Control Granola
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy, Appetite
Pasta Formulations, Portion Sizes and Their Effect on Appetite
Investigators are interested in learning how appetite responds to pasta containing different amounts of protein and fiber when provided in two different portion sizes.
- Trial name
- SET (NCT01199770)
- Testing
- Control, small, Experimental B, small, Experimental pasta C, small
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Bardet-Biedl Syndrome, POMC Deficiency
Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway
A trial to compare the weekly and daily formulations of setmelanotide in participants with genetic defects in the melanocortin-4 receptor pathway.
- Trial name
- NCT05194124
- Testing
- Setmelanotide 2 mg, Setmelanotide 2.5 mg, Setmelanotide 3 mg
- Where
- 7 sites in United States, Canada and 4 more
- Volunteers
- 19 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
High BMI, Hunger
A Clinical Trial to Determine the Safety and Efficacy of an Origin Satiety Complex on Self-reported Hunger and Satiety in Healthy Adults
The goal of this clinical trial is to the safety and efficacy of the investigational product (IP), Origin Satiety Complex, on hunger and satiety in healthy adults.
- Conditions
- High BMI, Hunger, Satiety, Healthy Adults
- Trial name
- NCT07390266
- Testing
- Origin Satiety Complex
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vora Life LLC
Obesity, Genetic Obesity
EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway
The protocol describes a randomized, double-blind, placebo-controlled trial with independent sub-studies of setmelanotide in patients with obesity and at least one of the specific gene variants in the Melanocortin-4 Receptor…
- Trial name
- NCT05093634
- Testing
- Setmelanotide
- Where
- 56 sites in United States, Canada and 8 more
- Volunteers
- 296 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity
Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks
GW869682 causes glucose to be excreted in the urine. The purpose of this study is to see whether enough calories from glucose are excreted in the urine to cause weight loss.
- Trial name
- NCT00297180
- Testing
- GW869682
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Glycemic Response, Insulinemic Response
Glycemic and Insulinemic Impact of a Test Granola 2 Versus a Control Granola
The objectives of this study are to examine the blood glucose and serum insulin response elicited by servings of Test Granola and Control Granola containing equal amounts of available carbohydrate over a 3 h time period.
- Conditions
- Glycemic Response, Insulinemic Response, Subject Hunger Response
- Trial name
- NCT03493022
- Testing
- Test Granola, Control Granola
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Eating Behavior
Effects of Low Calorie Sweeteners on Dietary Intakes, Hunger, Appetite and Satiety
Although there is evidence that low calorie sweeteners (LCS) do not stimulate hunger or appetite, divergent opinions appear regularly both in the scientific literature and in the popular press.
- Trial name
- NCT02297880
- Testing
- Beverage containing low calorie sweeteners, Still water
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The Coca-Cola Company
Nutrition, Healthy
Dose Response Effect of Chia Seeds on Subjective Appetite and Glycemic Response
To compare subjective appetite, satiety and glycemic responses for 3 h after consumption of investigational products containing 0, 3, 5 and 7 grams of chia seeds, controlling for energy intake.
- Trial name
- NCT05345470
- Testing
- 140 calories per 30 gram test meal
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Hunger, Satiety
Effect of Nutrition Bars on Satiety in Women
This study investigates nutrition bar consumption and possible impact on self-reported ratings of hunger and fullness compared to a control.
- Trial name
- NCT02091570
- Testing
- Nutrition Bar
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Blood Glucose; Subjective Hunger, Insulin
Glycemic and Insulinemic Impact of Oats With Additional Dried Fruits, Nuts and Seeds Soaked Overnight
The purpose of this study is to compare the glucose, insulin and subjective hunger responses elicited by oats with additional dried fruits, nuts and seeds soaked overnight in skim milk and consumed cold versus Cream of Rice…
- Trial name
- NCT03091946
- Testing
- Overnight oats with additional dried fruits, nuts and seeds, Cooked cream of rice with additional dried fruits, nuts and seeds
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Satiety of High Fiber High Protein Bread
Effect of EverVita Pro, a Protein Rich Ingredient, on Satiety Measures, Subsequent Energy Intake, and Gastrointestinal Symptoms: A Randomized, Controlled, Cross-over Study in Healthy Subjects
This study will explore the satiating effect of EverVita Pro when consumed at breakfast on subsequent food intake. On 2 separate days, subjects will consume in random order a test breakfast (bread, butter, jam), either containing…
- Trial name
- NCT04869215
- Testing
- EverVita Pro, Control bread
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evergrain, LLC
Hyperphagia, Prader-Willi Syndrome
The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial
The goal of this clinical trial is to learn if ARD-101 works to treat hyperphagia-related behavior in patients with Prader-Willi syndrome (PWS) when used in a long term setting. It will also teach us about the safety of ARD-101.
- Conditions
- Hyperphagia, Prader-Willi Syndrome, Hyperphagia in Prader-Willi Syndrome
- Trial name
- NCT07197034
- Testing
- ARD-101
- Where
- 30 sites in United States, Australia and 3 more
- Volunteers
- 19 people
- Sponsor
- Aardvark Therapeutics, Inc.
Micronutrient Deficiencies
The Effect of Micronutrient Supplementation on Nutrition Status and Well-being
Inadequate micronutrient status poses a significant challenge in Sub-Saharan African countries, including Ghana, and affects various demographics.
- Trial name
- NEXUS (NCT07031973)
- Testing
- Active Effervescent Powder, Nutrition training and healthy lifestyle coaching
- Where
- Ghana
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- InnoNext Sarl
Hunger
A Study of Chewing Gum, Snacking and Appetite
Investigators are interested in learning how appetite responds after chewing gum. In this research study subjects will be asked to eat a lunch meal provided at our Center.
- Trial name
- GUM (NCT01316991)
- Testing
- Chewing Gum, No Gum
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology