Clinical trials: Hyaluronic Acid
Oesophageal Reflux, Gastric Reflux
Efficacy and Speed of Action of a Product to Control Gastric Hydration and Gastroesophageal Reflux
A Randomised, Placebo-Controlled Clinical Trial off the Efficacy and Rapidity of Action of a Product Containing Sodium Alginate, Calcium and Magnesium Salts, Hyaluronic Acid and Aloe Vera to Control Oesophageal-Gastric pH and…
- Conditions
- Oesophageal Reflux, Gastric Reflux, Hyperactivity; Stomach
- Trial name
- AQUAA (NCT05060744)
- Testing
- Antacid, Control
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Uriach Consumer Healthcare
Nasolabial Folds
TEOSYAL® PureSense ULTRA DEEP Versus Restylane® Lidocaine for the Correction of Moderate to Severe Nasolabial Folds in Chinese Adults
This is a prospective, multi-center, randomized, controlled, subject- and evaluator-blinded clinical investigation to demonstrate non-inferiority of TEOSYAL® PureSense ULTRA DEEP compared to Restylane® Lidocaine for the…
- Trial name
- NCT06367634
- Testing
- injection in NLF
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Acne Vulgaris, Folliculitis
Evaluation of Safety and Performance of Ialuxid Gel in Treatment of Acne Vulgaris, and Folliculitis
The Research Question of the present study is the following: in a population of men and women affected by acne vulgaris, and folliculitis, will Ialuxid® Gel (hydrogen peroxide, hyaluronic acid and glycine) improve the course of…
- Trial name
- NCT05345093
- Testing
- Ialuxid gel
- Where
- Romania
- Volunteers
- 66 people
- Sponsor
- BMG Pharma
Blepharitis, Blepharoconjunctivitis
Performance and Safety of IRIDIUM GARZE in Blepharitis or Blepharconjunctivitis Adjuvant Treatment
The study will evaluate the clinical improvement in ocular symptoms using IRIDIUM GARZE as adjuvant treatment in patients suffering of blepharitis or blepharoconjunctivitis as primary objective.
- Trial name
- NCT07431385
- Testing
- IRIDIUM GARZE
- Where
- 5 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Lip Augmentation
A Study to Evaluate the Safety and Performance of Dr Korman Laboratories' Hyaluronic Acid Filler 20 mg/mL With Lidocaine for Lip Augmentation
This study will assess the safety and effectiveness of a dermal filler called DKL crosslinked hyaluronic acid 20 mg/mL with lidocaine 0.3% when injected into the lips of healthy men and women who want to have fuller lips.
- Trial name
- NCT07204691
- Testing
- DKL crosslinked sodium hyaluronate 20 mg/mL + Lidocaine 0.3% dermal filler
- Where
- 2 sites in Sweden
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Cataract
Clinical Investigation of the Bacterially-Derived Healon5 Ophthalmic Viscosurgical Device (OVD)
Prospective, multicenter, paired-eye, randomized, masked, clinical trial of the bacterially-derived Healon5 OVD versus the currently available Healon5 OVD control.
- Trial name
- NCT02782676
- Testing
- Investigational Healon5 OVD, Healon5 OVD
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Osteo Arthritis of the Knee
A Study to Evaluate Efficacy and Safety of a Single Intra-Articular Injection of HL-01 in the Treatment of Pain in Symptomatic Knee Osteoarthritis
The goal of this clinical trial is to test HL-01 in patients with knee osteoarthritis pain. The main question[s] it aims to answer are: Measure the change in average daily knee pain intensity scores from baseline to the end of…
- Trial name
- NCT07819461
- Testing
- Sodium hyaluronate solution - 3.36%, Sterile buffered solution
- Volunteers
- 704 people
- Sponsor
- IBSA Institut Biochimique SA
Healthy
Pharmacokinetic and Safety Study of HYLENEX Recombinant-Augmented Subcutaneous Ceftriaxone Administration
The objectives of this study are: to establish the safety of subcutaneous administration of ceftriaxone at different concentrations, with and without HYLENEX recombinant, and to determine the maximum tolerated concentration; and…
- Trial name
- INFUSE-Cftrx (NCT00493220)
- Testing
- SC HYLENEX and Ceftriaxone, IV Ceftriaxone
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Skin Aging, Skin Wrinkling
Evaluation of the Safety and Efficacy of an Injectable Liposomal Gel
The aim of this study is to evaluate the efficacy and safety of intradermal injections of the medical device - hyaluronic acid with the addition of lecithin - in a population of participants with thin, dry, and sagging facial…
- Conditions
- Skin Aging, Skin Wrinkling, Facial Skin Laxity, Facial Wrinkles
- Trial name
- DensiStim (NCT06997380)
- Testing
- Injection of the investigational product via needle, Injection of the investigational product via cannula, Clinical assessment
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Biovico Sp. z o.o.
Allergic Conjunctivitis of Both Eyes
Daydrop® Triple Action for Allergic Eye Symptoms
The study is designed to evaluate the safety and efficacy of Daydrop® Triple Action for the symptomatic treatment of seasonal or perennial allergic conjunctivitis.
- Trial name
- NCT07805759
- Testing
- Eye Drops, Lubricant
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- i+Med S.Coop.
Skin Laxity, Skin Roughness
Aesthetic Performance and Tolerance of an Injective Intradermal Treatment for the Skin Roughness and Laxity of Back of the Hands
People lose collagen all over the body, not just in the face; skin roughness and laxity of the dorsum of the hands can result from chrono and photo-aging.
- Trial name
- NCT05590364
- Testing
- Profhilo® Body
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Osteoarthritis, Hip
6-month Efficacy and Safety of Synolis VA 80/160 in Hip Osteoarthritis
Multicenter, independent study of Synolis VA 80/160 over a period of 6 months
- Trial name
- NCT05829733
- Testing
- SYNOLIS VA 80/160
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- Aptissen SA
Knee Osteoarthritis
Efficacy and Safety Study in Patients Suffering From Knee Osteoarthritis
The primary objective of this study is to compare a combination of hyaluronic acid and chondroitin sulfate (V0220) to Hyalgan® on pain relief in patients with symptomatic knee osteoarthritis (OA) over 24 weeks when administered…
- Trial name
- VESTA (NCT01469507)
- Testing
- Chondroitin sulfate and sodium hyaluronate, Hyaluronan
- Sponsor
- Pierre Fabre Medicament
Dry Eye Syndromes
Non Interventional Study to Evaluate the Efficacy and Tolerability of Ectoin Containing Ophthalmic Solution
This is a comparative, open label, parallel group, non interventional study to further demonstrate the efficacy and tolerability of BAT04. In addition the efficacy and safety shall be compared to Hyaluronic acid (HA)-Product.
- Trial name
- NCT01684852
- Testing
- Medical device, drug-like
- Where
- 5 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Bitop AG
Wound Heal, Wound; Foot
Management of Acute and Chronic Wounds With Hyaluronic Acid
The purpose of this study is to evaluate the performance and safety of Connettivina Bio, when used in the management of wounds. Moreover, the study will evaluate the correlation of the 'dressing system' (formed by the…
- Trial name
- NCT06108999
- Testing
- Connettivina BIO cream and gauze
- Where
- 3 sites in Italy
- Volunteers
- 170 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Dermal Filler
Formaderm (Hyaluronic Acid) for Facial Soft Tissue Augmentation
The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm (hyaluronic acid) dermal filler injection for soft tissue augmentation.
- Trial name
- NCT05822778
- Testing
- Formaderm Dermal Filler Injection, "Q-MED" RESTYLANE
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Maxigen Biotech Inc.
Vocal Fold Palsy, Vocal Cord Paralysis
A Histological Study Evaluating Silk Voice and Crosslinked Hyaluronic Acid
The primary study goal is to evaluate the histological characteristic of Silk Voice to evaluate the potential for Silk Voice to deliver long-term results to patients.
- Conditions
- Vocal Fold Palsy, Vocal Cord Paralysis, Vocal Cord Atrophy
- Trial name
- NCT04315415
- Testing
- Silk Voice
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sofregen Medical, Inc.
Knee Osteoarthritis
Efficacy of OSTENIL PLUS (Hyaluronic Acid) Versus SYNVISC-ONE in Patients With Tibiofemoral Osteoarthritis
The main objective of the study was to demonstrate the non-inferiority of the efficacy of a single intra-articular injection of OSTENIL PLUS compared to that of a single intra-articular injection of the reference product…
- Trial name
- NCT03203408
- Testing
- OSTENIL PLUS, SYNVISC-ONE
- Volunteers
- 290 people
- Sponsor
- TRB Chemedica
Osteoarthritis, Knee
The Comparison of Two Crosslinked Hyaluronate for the Treatment of Osteoarthritis Pain
The aim of this study is to compare the safety and effectiveness between two BDDE-crosslinked hyaluronate, HYAJOINT Plus and Durolane, for the Treatment of Knee Osteoarthritis Pain.
- Trial name
- NCT04000204
- Testing
- HYAJOINT Plus, Durolane
- Where
- Taiwan
- Volunteers
- 142 people
- Sponsor
- SciVision Biotech Inc.
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA