Clinical trials: Hydrocephalus.
Hydrocephalus, Normal Pressure
Assessment of ShuntCheck Performance Characteristics in Asymptomatic Patients With Normal Pressure Hydrocephalus
The purpose of the study is to determine if the ShuntCheck test can correctly identify flow or no flow in a ventriculoperitoneal shunt in patients with asymptomatic normal pressure hydrocephalus.
- Trial name
- NCT04011566
- Testing
- ShuntCheck
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of South Florida
Hydrocephalus, Idiopathic Intracranial Hypertension
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
This research is being done to determine the accuracy of two noninvasive methods of measuring the pressure of the cerebrospinal fluid (CSF), also known as intracranial pressure or ICP.
- Conditions
- Hydrocephalus, Idiopathic Intracranial Hypertension, Pseudotumor Cerebri
- Trial name
- NCT01863381
- Testing
- Tympanic membrane displacement (TMD), DPOAE
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- LifeBridge Health
Disorder of Consciousness, Hydrocephalus
Prediction Model of Improvement of Disturbance of Consciousness in Patients With Hydrocephalus After Shunt Operation
Patients with hydrocephalus are usually treated with cerebrospinal fluid (CFS) shunt to deal with excess cerebrospinal fluid in the brain.
- Trial name
- NCT05237102
- Testing
- Cerebrospinal fluid shunt
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhuohang Wang
Meningioma, Tumor, Brain
MiDura-Study (Neuro-Patch in Duraplasty)
The aim of this study is to collect systematically and proactively data regarding the performance of Neuro-Patch, like complications and handling, under daily clinical practice when used as intended by the manufacturer
- Conditions
- Meningioma, Tumor, Brain, Chiari Malformation, Vascular Malformation
- Trial name
- MiDura (NCT04189172)
- Where
- 4 sites in France, Germany
- Volunteers
- 328 people
- Sponsor
- Aesculap AG
Obstructive Hydrocephalus, Subarachnoid Hemorrhage
VisAR Augmented Reality Navigation of Ventriculostomy
This study is intended to evaluate the feasibility of using VisAR augmented reality surgical navigation during placement of an external ventricular drain (EVD).
- Conditions
- Obstructive Hydrocephalus, Subarachnoid Hemorrhage, Brain Trauma
- Trial name
- NCT06132139
- Testing
- VisAR
- Volunteers
- 50 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hydrocephalus, Hydrocephalus in Children
A Secondary Study Evaluating Aqueduct's Smart External Drain (SED)
Aqueduct's Smart External Drain (SED) will be compared to the current gold standard for temporary CSF management in a hospital setting.
- Conditions
- Hydrocephalus, Hydrocephalus in Children, Tumor, Brain, Subarachnoid Hemorrhage
- Trial name
- NCT03471702
- Testing
- Smart External Drain - SED
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Aqueduct Critical Care
Hydrocephalus
Improving Infant Hydrocephalus Outcomes in Uganda
Neonatal postinfectious hydrocephalus (PIH) is a major public health problem in East Africa.The standard treatment has long been placement of a ventriculoperitoneal shunt (VPS) but these devices require life-long maintenance and…
- Trial name
- NCT03650101
- Testing
- ETV/CPC
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 400 people
- Sponsor
- Boston Children's Hospital
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Hydrocephalus
Caregiver Burden and Anxiety in Mothers of Children With Hydrocephalus
This study is being conducted in randomized controlled trial design to determine the effect of the education given to the mothers of children with hydrocephalus on caregiver burden and anxiety levels.
- Trial name
- NCT05544279
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Hydrocephalus
Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device
This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow. Patients with an existing implanted shunt will wear the device to acquire longitudinal data.
- Trial name
- NCT06086561
- Testing
- Thermal Anisotropy Measurement Device
- Where
- 4 sites in United States
- Volunteers
- 130 people
- Sponsor
- Rhaeos, Inc.
Hydrocephalus, Hydrocephaly
Hydrocephalus iPad-App Based Intervention Study
This is a pilot study examining the feasibility and efficacy of using Apple iPad applications ("apps") during therapy interventions that target visual motor, visual attention, and visual-spatial reasoning skills in school age…
- Conditions
- Hydrocephalus, Hydrocephaly, Hydrocephalus in Children
- Trial name
- NCT03595033
- Testing
- iPad app-based intervention
- Volunteers
- 14 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Neurocysticercosis
People Presenting With Neurocysticercosis in North America
Background: Neurocysticercosis (NCC) is caused by tapeworms that infect people. NCC can lead to serious brain problems such as seizures, sevre headaches and difficulties with movements or sensation in the limbs.
- Trial name
- NCT02233855
- Where
- 4 sites in United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hydrocephalus in Infants
Cerebrospinal Fluid Proteom in Dependence of Intranasal Breast Milk
Investigation of the cerebrospinal fluid proteom in preterm infants with posthemorrhagic hydrocephalus in our neonatology center with analysis for modulation of proteom in dependence of breastmilk feeding and way of application…
- Trial name
- NAMU (NCT04229693)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital of Cologne
Hematoma Intracranial, Hydrocephalus
Subgaleal Drains in Decompressive Craniectomies
This research is about the use of subgaleal drains to prevent accumulation of blood under the skin in patients undergoing surgery to remove part of the skull(craniectomy) and its associated complications.
- Conditions
- Hematoma Intracranial, Hydrocephalus, Surgical Site Infection, Wound Breakdown
- Trial name
- VADER (NCT03777774)
- Testing
- Passive Redon subgaleal drains, Vacuum Redon subgaleal drains, No Redon subgaleal drains
- Where
- 2 sites in Malaysia
- Volunteers
- 78 people
- Sponsor
- Universiti Sains Malaysia
Hydrocephalus, Normal Pressure, Hydrocephalus
US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus
The eShunt® System is a minimally invasive method of treating communicating hydrocephalus. The eShunt System includes a proprietary eShunt Delivery System and the eShunt Implant, a permanent implant deployed in a minimally…
- Trial name
- NCT05232838
- Testing
- eShunt Implant
- Where
- 11 sites in United States
- Volunteers
- 50 people
- Sponsor
- CereVasc Inc
Idiopathic Normal Pressure Hydrocephalus (INPH)
Walking Pattern Characteristics in Normal Pressure Hydrocephalus
20 patients who are diagnosed with NPH receive a set of 5 wearable gyroscopes (IMUs, ZurichMove sensors) for a period of 3 days for measurement and characterization of their walking in an ambulatory setting.
- Trial name
- NPH wearables (NCT04702035)
- Testing
- Characterization of walking pattern characteristics in an ambulatory setting using wearable IMUs (ZurichMOVE sensors)
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Post-hemorrhagic Hydrocephalus (PHH)
Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage
Hydrocephalus is a serious condition in which fluid builds up inside the brain, often requiring lifelong surgical placement of a shunt to drain excess cerebrospinal fluid (CSF).
- Trial name
- VENTURE-PHH (NCT07662174)
- Testing
- Sirolimus (Rapamune®)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Idiopathic Normal Pressure Hydrocephalus, Normal Pressure Hydrocephalus
Prediction of Response to Shunt Surgery in Normal Pressure Hydrocephalus Using Radscale and Lumbar Puncture
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder in older adults characterized by walking difficulties, cognitive decline, and urinary dysfunction.
- Trial name
- NCT07832877
- Volunteers
- 40 people
- Sponsor
- Assiut University
Hydrocephalus, Normal Pressure Hydrocephalus
The Usage of Telemetric Prechamber Sensor Reservoir in Management of Normal Pressure Hydrocephalus. Comparisson of Benefit for Patients with Implanted Telemetric Prechamber Sensor Reservoir.
Normal pressure hydrocephalus (NPH) is a preventable and treatable cause of dementia. However, as a nosological entity, it is significantly underdiagnosed, often being mistakenly classified as presenile or senile dementia without…
- Conditions
- Hydrocephalus, Normal Pressure Hydrocephalus, Normal Pressure Hydrocephalus Patients
- Trial name
- NCT06629168
- Testing
- lumbar puncture, External lumbar drainage, Ventriculo-peritoneal shunt placement
- Where
- Czechia
- Volunteers
- 33 people
- Sponsor
- University Hospital Hradec Kralove
Hydrocephalus, Intracranial Hypertension
Brain Ultrasound in the Weaning of External Ventricular Leads
External Ventricular Deviation (EDV) is a medical device that provides transient and controlled external drainage of cerebrospinal fluid (CSF). This device can also monitor intracranial pressure (ICP).
- Trial name
- ECHO-SD (NCT03531723)
- Testing
- Measuring the size of the 3rd ventricle by ultrasound
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse