Clinical trials: Hyperbaric
Disorders of Consciousness, Vegetative State
AI-Assisted Precision Hyperbaric Oxygen Therapy Based on Dynamic BIS-EEG Feedback for Patients With Disorders of Consciousness
Disorders of consciousness (DoC) are severe neurological conditions characterized by impaired awareness and reduced interaction with the environment.
- Conditions
- Disorders of Consciousness, Vegetative State, Minimally Conscious State
- Trial name
- AI-HBOT-DoC (NCT07855848)
- Testing
- AI-Assisted Personalized Hyperbaric Oxygen Therapy, Conventional Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Diabetes Mellitus, Claudication, Intermittent
Additional Hyperbaric Oxygen After Lower Extremity Amputation
This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment group receiving hyperbaric oxygen therapy, or…
- Conditions
- Diabetes Mellitus, Claudication, Intermittent, Critical Limb Ischemia, Osteomyelitis
- Trial name
- AHOLEA (NCT03594344)
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Microcirculation, Wound Healing
Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?
This study aims to test the hypothesis that postoperative daily hyperbaric oxygen therapy (HBOT) decreases soft-tissue complication rate during the operative handling of intra-articular calcaneal fractures. Minor motivations: 1.
- Trial name
- HOCIF (NCT01264146)
- Testing
- HBOT
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Geriatric Patient, Spinal Anesthesia
Comparison of Hemodynamic Effects of Hypobaric and Hyperbaric Bupivacaine in Spinal Anesthesia in Geriatric Patients
The frequency of hypotension is increased in geriatric patients due to physiological changes compared to the normal population. In this study, our aim is to compare the hemodynamic changes in geriatric patients undergoing hip…
- Conditions
- Geriatric Patient, Spinal Anesthesia, Hip Surgery
- Trial name
- NCT06972485
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Eskisehir Osmangazi University
Breast Cancer, Radiation Toxicity
The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY - UMBRELLA HONEY Trial
The "Hyperbaric OxygeN therapy on brEast cancer patients with late radiation toxicity" (HONEY) trial aims to evaluate the effectiveness of HBOT on late radiation toxicity in breast cancer patients using the trial within cohorts…
- Trial name
- HONEY (NCT04193722)
- Testing
- Hyperbaric oxygen therapy
- Where
- Netherlands
- Volunteers
- 189 people
- Sponsor
- UMC Utrecht
Impotence, Prostatic Neoplasms
Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer
The purpose of this study is to determine if adding hyperbaric oxygen therapy, a therapy that delivers oxygen under slight pressure, to a drug treatment of PDE5I (such as Viagra, Levitra, Cialis)for men following surgery for…
- Trial name
- HBOT (NCT00906269)
- Testing
- Sildenafil therapy plus post-NSRRP HBO2T
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hartford Hospital
Cancer
Hyperbaric Oxygenation Treatment and Quality of Life
Osteoradionecrosis, dermal soft tissue necrosis, radiation cystitis, proctitis and sexual dysfunctions are well-known late-effects after radiation for cancer in the pelvic area, negatively affecting the survivors' quality of life…
- Trial name
- NCT03570229
- Testing
- Hyperbaric oxygen treatment
- Where
- Norway
- Volunteers
- 137 people
- Sponsor
- University of Bergen
Postoperative Delirium, Hip Fractures
Intrathecal Dexmedetomidine and Postoperative Delirium in Elderly Hip Fracture Surgery
Postoperative delirium (POD) is a common and serious complication in elderly patients undergoing surgical repair for hip fractures, often triggered by acute pain, surgical stress, neuroinflammation, and opioid consumption.
- Trial name
- NCT07810556
- Testing
- Dexmedetomidine, Hyperbaric Bupivacaine with Normal Saline
- Volunteers
- 130 people
- Sponsor
- Assiut University
Acute Ischemic Stroke
Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Ischemic Stroke Recovery (Pro00061930)
This study will critically examine the feasibility, safety and efficacy of HBOT during inpatient rehabilitation (IPR) after acute ischemic stroke measured by non-disruption of 3 hours of daily therapy, frequency of neurological…
- Trial name
- NCT06148285
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- LCMC Health
Carbon Monoxide Poisoning, Carbon Monoxide Intoxication
Carbon Monoxide Hyperbaric Oxygen With Steroid Therapy
Hyperbaric Oxygen Therapy (HBO) is routine treatment of carbon monoxide (CO) poisoning to prevent delayed neurological sequelae. This study looking to see if neurologic outcomes are improved with the addition of dexamethasone.
- Conditions
- Carbon Monoxide Poisoning, Carbon Monoxide Intoxication, Carbon Monoxide Encephalopathy, Carbon Monoxide-induced Parkinsonism
- Trial name
- CODex (NCT06574048)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Oxygen Toxicity, Oxidative Stress
Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity
The goal of this trial is to investigate whether adding a small fraction of hydrogen gas to an oxygen-enriched breathing mixture can reduce pulmonary oxygen toxicity (POT) in healthy and active divers from the Swedish Armed…
- Conditions
- Oxygen Toxicity, Oxidative Stress, Hyperoxia, Hyperbaric Oxygen
- Trial name
- NCT07263399
- Testing
- Inhaled Hydrogen-Enriched Oxygen Gas, Inhaled Nitrogen-Enriched Oxygen Gas
- Where
- 2 sites in Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Hyperbaric Oxygen Therapy, Neuroprotective
Hyperbaric Oxygen Therapy as a Neuroprotective Intervention in Pediatric Acquired Brain Injury With Cognitive Disability
This research aimed to investigate the effectiveness of hyperbaric oxygen therapy as a neuroprotective strategy for improving neurological outcomes in pediatric patients who have sustained acquired brain injury.
- Conditions
- Hyperbaric Oxygen Therapy, Neuroprotective, Pediatric, Acquired Brain Injury
- Trial name
- NCT06954376
- Testing
- Hyperbaric oxygen therapy, Conventional rehabilitation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kafrelsheikh University
Interstitial Cystitis
Comparative Study Between Hyperbaric Therapy and Intravesical Dimethyl Sulfoxide Instillation for Interstitial Cystitis
The purpose of this study is to compare the efficacy of hyperbaric oxygen therapy (HBOT) to intravesical Dimethyl Sulfoxide (DMSO) instillation for the treatment of patients who suffers from Interstitial Cystitis / Painful…
- Trial name
- NCT01069263
- Testing
- Hyperbaric Oxygen Therapy, DMSO
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Traumatic Brain Injury, Post-traumatic Stress Disorder
Hyperbaric Oxygen Therapy in Chronic Traumatic Brain Injury or Post-Traumatic Stress Disorder
This is an observational research study whose purposes are to see: 1. if 40 Hyperbaric Oxygen Therapy sessions at 1.5 atmospheres (HBOT 1.5) or more (60, or 80 HBOT's) help, worsen, or have no effect on subjects with chronic…
- Trial name
- NBIRR-1 (NCT01105962)
- Where
- 10 sites in United States
- Volunteers
- 133 people
- Sponsor
- International Hyperbaric Medical Foundation
Intrathecal Dexmedetomidine
This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).
This study aims to determine whether lower doses (4 µg) of intrathecal dexmedetomidine can provide comparable analgesic benefits while minimizing adverse hemodynamic effects in patients encountered in our setup( Shifa…
- Trial name
- NCT07807020
- Testing
- Intrathecal Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Autism
Pilot Study of the Effect of Hyperbaric Oxygen Treatment on Behavioral and Biomarker Measures in Children With Autism
The purpose of this study is to increase the understanding of the effect of Hyperbaric Oxygen Treatment (HBOT) on the behavior and functioning of children with autism.
- Trial name
- HBOT (NCT00584480)
- Testing
- Hyperbaric Oxygen Treatment (HBOT)
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Diabetic Foot Ulcer
Effectiveness of Diabetic Recovery Shoes and Artificial Intelligence Supported Structured Exercise Program
This study aims to evaluate the effectiveness of the diabetic recovery sandal and artificial intelligence supported structured exercise program in individuals diagnosed with diabetic foot receiving hyperbaric oxygen therapy.
- Trial name
- NCT06515665
- Testing
- therapeutic foot orthosis
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hacettepe University
Tibial Fracture, Soft Tissue Injury
Hyperbaric Oxygen in Lower Leg Trauma
Study hypothesis :Hyperbaric Oxygen may prevent complications and improve outcomes in severe lower limb trauma. We propose to investigate this hypothesis by conducting an International multi centre randomised control trial of…
- Trial name
- NCT00264511
- Testing
- Hyperbaric Oxygen Treatment
- Where
- 10 sites in United States, Australia and 7 more
- Volunteers
- 120 people
- Sponsor
- Bayside Health
Intracranial Meningioma, Neurologic Deficits
Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery
The aim of the current study is to evaluate, in a prospective cross-over, randomized study, the effect of hyperbaric oxygen therapy (HBOT) on patients with chronic neurological deficits and cognitive impairment after anterior…
- Trial name
- NCT02084927
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Assaf-Harofeh Medical Center