Clinical trials: Hyperbaric
Chemical Peeling
Hyperbaric Therapy and Deep Chemical Peeling
To evaluate whether treatment with Hyperbaric oxygen can accelerate skin recovery after deep peeling, and decrease frequency and severity of local side effects and complications.
- Trial name
- NCT00425789
- Testing
- Treatment with Hyperbaric oxygen
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Stroke, Ischemic Stroke
Hyperbaric Oxygen Post Established Stroke
The purpose of this study is to examine the role of Hyperbaric Oxygen Therapy (HBOT) in improving neurological function in patients who are 6 to 36 months post ischemic stroke.
- Conditions
- Stroke, Ischemic Stroke, Established Stroke
- Trial name
- HOPES (NCT02582502)
- Testing
- Hyperbaric Oxygen
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of British Columbia
Chronic Pain, Complex Regional Pain Syndrome
Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome
The aim of the study is to investigate the efficacy of hyperbaric oxygen therapy as an adjunct in the management of severe complex regional pain syndrome.
- Trial name
- NCT07446712
- Testing
- Early hyperbaric oxygen therapy (HBOT), Delayed hyperbaric oxygen therapy (HBOT)
- Where
- 2 sites in Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava
Coma, Carbon Monoxide Poisoning
Carbon Monoxide-induced Coma: Prognostic Factors
The primary objective of the study is to determine prognostic factors for hospital-mortality following carbon monoxide (CO)-induced coma.
- Trial name
- Coma-CO (NCT03926494)
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carbon Monoxide Poisoning, Neurologic Sequelae
Adjunct Targeted Temperature Management in Acute Severe Carbon Monoxide Poisoning
This randomized trial will investigate important neurocognitive clinical outcomes of patients with acute severe carbon monoxide poisoning (ASCOP) randomized to receive either therapeutic hypothermia or normothermia combined with…
- Conditions
- Carbon Monoxide Poisoning, Neurologic Sequelae, Hypothermia
- Trial name
- NCT04975867
- Testing
- Targeted therapeutic hypothermia, Targeted therapeutic normothermia
- Where
- 2 sites in South Korea
- Volunteers
- 37 people
- Sponsor
- Wonju Severance Christian Hospital
Breast Reconstruction, Lipofilling
Hyperbaric Oxygen Therapy to Improve Autologous Fat Graft Intake in Irradiated Breast
The goal of this clinical trial is to learn if hyperbaric oxygen therapy (HBOT) enhances fat graft survival in lipofilling procedures in irradiated breast cancer patients.
- Conditions
- Breast Reconstruction, Lipofilling, Hyperbaric Oxygen Therapy
- Trial name
- NCT07140198
- Testing
- Hyperbaric Oxygen Therapy, Control
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University Hospital, Geneva
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Osteoradionecrosis
Hyperbaric Oxygen Treatment of Mandibular Osteoradionecrosis. A Randomized Clinical Study
There is currently not sufficient evidence that hyperbaric oxygen (HBO) benefits the surgical removal of necrotic bone in osteoradionecrosis patients.
- Trial name
- NCT00760682
- Testing
- Hyperbaric oxygen
- Where
- 4 sites in Denmark, Sweden and 1 more
- Volunteers
- 114 people
- Sponsor
- Lone Forner
Traumatic Brain Injury, Post-Concussion Syndrome
Cognitive Effects of Hyperbaric Oxygen Therapy (HBOT) After a Traumatic Brain Injury
This is a retrospective, single-center observational study evaluating the cognitive effects of hyperbaric oxygen therapy (HBOT) in adults who sustained a traumatic brain injury (TBI).
- Trial name
- NCT07883668
- Testing
- Hyperbaric Oxygen Therapy - HBOT
- Volunteers
- 1,000 people
- Sponsor
- Assaf-Harofeh Medical Center
Long COVID, Post Acute Sequelae of COVID-19
Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Therapy for the Treatment of Post COVID Condition
The RECLAIM study platform will be used to explore whether the use of Hyperbaric Oxygen therapy (HBOT) improves the symptoms of post covid cognitive dysfunction. Hyperbaric oxygen therapy is a well-established medical treatment.
- Conditions
- Long COVID, Post Acute Sequelae of COVID-19, Post-COVID-19 Condition
- Trial name
- RECLAIM-HBOT (NCT06452095)
- Testing
- Hyperbaric Oxygen therapy
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Autism, Oxidative Stress
Effect of Hyperbaric Therapy on Markers of Oxidative Stress in Children With Autism
This study will look at the changes taking place in the blood levels of key markers of oxidative stress. Oxidative stress is the biological equivalent of rust on a car. It changes vital cell chemistry.
- Trial name
- NCT00263367
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The International Child Development Resource Center
Fibromyalgia, Emotional Trauma
Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma
The investigators have previously studied the efficacy of hyperbaric oxygen therapy (HBOT) as a treatment for Fibromyalgia syndrome (FMS) in a prospective, active control, crossover clinical trial.
- Trial name
- NCT04316702
- Testing
- Hyperbaric oxygen therapy (HBOT) treatment, Cymbalta / Lyrica - Drug treatment
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Assaf-Harofeh Medical Center
Breast Cancer, Lung Metastasis
Concept-verification Clinical Trial on the Inhibition of Breast Cancer Lung Metastasis Progression by Hyperbaric Oxygen
This is a proof-of-concept clinical trial focused on exploring whether hyperbaric oxygen therapy (HBOT) can inhibit the progression of lung metastasis in breast cancer patients.
- Conditions
- Breast Cancer, Lung Metastasis, Hyperbaric Oxygen Therapy
- Trial name
- HBOIBCLM (NCT07514728)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jinan Central Hospital
Diabetic Foot Ulcers
Hyperbaric Oxygen, Oxidative Stress, NO Bioavailability and Tissue Oxygenation
Hyperbaric oxygen therapy (HBOT) increases tissue oxygenation and serves as an adjunct therapy for diabetic wounds. However, some patients have insufficient increase or even paradoxical decrease in tissue O2 due to…
- Trial name
- NCT00463671
- Testing
- N-acetylcysteine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Spinal Anesthesia Evaluation, Cesarean Delivery
Dose-to-block Level Relation in Single Shot Spinal Anesthesia for Cesarean Section.
The study is designed to support or deny relation between the dose of hyperbaric bupivacaine given intrathecally and extent of spinal block level.
- Trial name
- SpinDoBlock (NCT06729567)
- Testing
- Spinal block level analysis, data collection
- Where
- Poland
- Volunteers
- 362 people
- Sponsor
- Centre of Postgraduate Medical Education
Traumatic Brain Injury
Hyperbaric Treatment of Traumatic Brain Injury (TBI)
This study is designed to test the hypothesis that patients with Traumatic Brain Injury (TBI)treated with Hyperbaric (HBO) will show improvement in function and an increased blood flow as evidenced by single-photon emission…
- Trial name
- TBI (NCT01847755)
- Testing
- Oxygen at 1.5 ATA (atmospheres absolute).
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Barry Miskin, MD
Periodontal Disease
Periodontal Treatment Associated With Hyperbaric Oxygen Therapy
Evaluation of the clinical effect of hyperbaric oxygen therapy (HBOT) adjunctively to scaling and root planing (SRP) in the treatment of severe case of chronic periodontitis.
- Trial name
- NCT00955643
- Testing
- oxygen, other
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Escola Bahiana de Medicina e Saude Publica
Arthroplasty, Knee
Effect of Body-mass Index (BMI) on Median Effective Dose of Intrathecal Hyperbaric Bupivacaine
The effect of Body-mass index (BMI) on requirements of local anesthetics used in spinal anesthesia has not been well established.
- Trial name
- NCT01291186
- Testing
- BPV6NO, BPV7NO, BPV8NO
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul Medical Center
Acute Acoustic Trauma
Efficacy of Various Treatments for Acute Acoustic Trauma.
Acute acoustic trauma is a growing concern in the IDF. there is currently no accepted treatment. The present retrospective study is intended to evaluate the efficacy of different treatment modalities in the IDF between 01/01/2010…
- Trial name
- NCT04482998
- Testing
- No intervention - retrospective study
- Where
- Israel
- Volunteers
- 250 people
- Sponsor
- Medical Corps, Israel Defense Force
Oxygen Toxicity, Oxidative Stress
Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity
The goal of this trial is to investigate whether adding a small fraction of hydrogen gas to an oxygen-enriched breathing mixture can reduce pulmonary oxygen toxicity (POT) in healthy and active divers from the Swedish Armed…
- Conditions
- Oxygen Toxicity, Oxidative Stress, Hyperoxia, Hyperbaric Oxygen
- Trial name
- NCT07263399
- Testing
- Inhaled Hydrogen-Enriched Oxygen Gas, Inhaled Nitrogen-Enriched Oxygen Gas
- Where
- 2 sites in Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology