Clinical trials: Hyperbaric
Radiation Injury, Radiation-Induced Complications
Hyperbaric Oxygen Therapy for Treatment of Severe Radiation-Induced Complications
This study evaluates the safety and effectiveness of hyperbaric oxygen therapy (HBOT) for the treatment of severe radiation-induced complications in patients previously treated with radiotherapy.
- Conditions
- Radiation Injury, Radiation-Induced Complications, Radiation Necrosis
- Trial name
- NCT07422168
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- Slovenia
- Volunteers
- 39 people
- Sponsor
- Institute of Oncology Ljubljana
Obesity, Type 2 Diabetes
Hyperbaric Oxygen Treatment Ameliorates Insulin Resistance
Obesity is an epidemic in Western society and is the biggest risk factor for insulin resistance and type 2 diabetes. The investigators have preliminary evidence showing that hyperbaric oxygen therapy rapidly increases insulin…
- Trial name
- HOTAIR (NCT01361971)
- Testing
- Hyperbaric Oxygen Treatment
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Hyperbaric Oxygen Therapy, Diabetic Foot Ulcer
Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine
The investigators want to evaluate the short duration HBOT can improve glycohemoglobin (HbA1c) levels, leukocyte count, and serum creatinine levels in patients with DFU (diabetic foot ulcer) Wagner 3-4.
- Conditions
- Hyperbaric Oxygen Therapy, Diabetic Foot Ulcer, Type II Diabetes Mellitus
- Trial name
- NCT03615755
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Volunteers
- 30 people
- Sponsor
- Hendry Irawan
Diabetes, Peripheral Arterial Disease
Postoperative Hyperbaric Oxygen Treatments to Reduce Complications in Diabetic Patients Undergoing Vascular Surgery
This trial aims to evaluate if hyperbaric oxygen treatment (HBO) given postoperatively is effective in reducing healing time and wound complications after lower extremity bypass surgery in patients with diabetes.
- Conditions
- Diabetes, Peripheral Arterial Disease, Arterial Occlusive Disease
- Trial name
- HODiVA (NCT01002209)
- Testing
- Hyperbaric Oxygen treatment (HBO)
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Fibromyalgia, Emotional Trauma
Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma
The investigators have previously studied the efficacy of hyperbaric oxygen therapy (HBOT) as a treatment for Fibromyalgia syndrome (FMS) in a prospective, active control, crossover clinical trial.
- Trial name
- NCT04316702
- Testing
- Hyperbaric oxygen therapy (HBOT) treatment, Cymbalta / Lyrica - Drug treatment
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Assaf-Harofeh Medical Center
Acute Myeloid Leukemia, Myelodysplastic Syndromes
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant
The purpose of this study is to determine if hyperbaric oxygen therapy is safe in the setting of stem cell transplantation. This study will also determine if hyperbaric oxygen therapy improves engraftment, graft versus host…
- Conditions
- Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia
- Trial name
- NCT03964506
- Testing
- Hyperbaric oxygen
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Omar Aljitawi
Oxygen Toxicity
Pulmonary Function After Hyperbaric Oxygen Therapy
Patients receiving hyperbaric oxygen therapy (HBOT) for any indication at the Hyperbaric Medicine Unit (University Health Network, Toronto, ON, Canada) from 2016-2021 were recruited to this prospective cohort study.
- Trial name
- NCT05088772
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- University of Toronto
Amputation; Postoperative, Sequelae
Hyperbaric Oxygen and Outcome After Below Knee Amputations
This study is being conducted to assess the utility of hyperbaric oxygen as an adjunctive treatment to reduce postoperative complications.
- Trial name
- NCT04717557
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Duke University
COVID-19, Desaturation of Blood
Hyperbaric Oxygen Therapy Effect in COVID-19 RCT (HBOTCOVID19)
The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic.So far, no specific treatment has proven efficacy. Recent case series reported the use of Hyperbaric Oxygen Therapy (HBOT) on 5 severe COVID-19 patients…
- Trial name
- HBOTCOVID19 (NCT04358926)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Post-COVID ME/CFS
Hyperbaric High Pressure Oxygen Therapy in Post-COVID Syndrome and ME/CFS
The objective of this observational study is to document symptom progression in 60 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) who undergo Hyperbaric Oxygen Therapy (HBOT) following COVID or other…
- Trial name
- NCT06118138
- Testing
- Hyperbaric oxygen therapy (HBOT)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Malignant Glioma, High Grade Glioma
Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.
This is a pilot study of radiotherapy using Hypofractionated image - guided helical tomotherapy after hyperbaric oxygen HBO therapy for treatment of recurrent malignant High-grade gliomas.
- Conditions
- Malignant Glioma, High Grade Glioma, Recurrent Glioma
- Trial name
- HBO-RT (NCT03411408)
- Testing
- HBO, RT
- Where
- 3 sites in Italy
- Volunteers
- 24 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Brain and Central Nervous System Tumors
Radiation Therapy Plus Hyperbaric Oxygen in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Hyperbaric oxygen may increase the effectiveness of radiation therapy.
- Trial name
- NCT00006460
- Testing
- hyperbaric oxygen, radiation therapy
- Where
- United States
- Sponsor
- Barrett Cancer Center
Hyperbaric Oxygen Therapy, Neuroprotective
Hyperbaric Oxygen Therapy as a Neuroprotective Modality in Pediatric Acquired Brain Injury With Motor Disability
This study aimed to assess the efficacy of hyperbaric oxygen therapy as a neuroprotective intervention in children with acquired brain injury.
- Conditions
- Hyperbaric Oxygen Therapy, Neuroprotective, Pediatric, Acquired Brain Injury
- Trial name
- NCT06954389
- Testing
- Hyperbaric oxygen therapy, Conventional rehabilitation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kafrelsheikh University
Brain Injury, Chronic
Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury
The purpose of this study is to examine whether 40 hyperbaric oxygen sessions has effect on long-term symptoms after brain injury.
- Trial name
- HYBOBI2 (NCT01986205)
- Testing
- Hyperbaric Oxygen, Minimal pressure air
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Lindell Weaver
SARS (Severe Acute Respiratory Syndrome), Cytokine Storm
Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19
COVID-19 may cause severe pneumonitis that require ventilatory support in some patients, the ICU mortality is as high as 62%. Hospitals do not have enough ICU beds to handle the demand and to date there is no effective cure.
- Conditions
- SARS (Severe Acute Respiratory Syndrome), Cytokine Storm, ARDS, Human, COVID-19
- Trial name
- COVID-19-HBO (NCT04327505)
- Testing
- Hyperbaric oxygen
- Where
- 3 sites in Germany, Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska Institutet
Acute Stroke
Effects of Repetitive Hyperbaric Oxygen Therapy in Patients With Acute Ischaemic Stroke
Background and Rationale: Cerebrovascular disease is always ranked at the top causes of death and most of hospitalized acute stroke patients have ischemic stroke [1].
- Trial name
- NCT03431402
- Testing
- Hyperbaric oxygen
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Cognitive Change
Oxygen as a Limiting Factor for Performing Multitasking
The aim of the present study was to evaluate whether hyperbaric oxygen (HBO) environment, with increased oxygen supply to the brain, will enable better performance of complex and/or multiple activities.
- Trial name
- NCT03126669
- Testing
- Hyperbaric oxygen, Hyperbaric chamber, normal air
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Stroke, Hyperbaric Oxygen
Hyperbaric Oxygen in Patients Who Had a Stroke
Prospective clinical assessment of 40 Hyperbaric Oxygen (HBO) treatments in 10 completed stroke patients.
- Trial name
- HOST (NCT04297358)
- Testing
- Hyperbaric oxygen
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Hyperbaric Center Basel
Oxidative Stress, Stem Cell Research
Enriched Oxygen Mixtures in Athletes
Currently, Hyperbaric Oxigen (HBO) is a widely used treatment for several conditions. There are 14 indications for HBO, officially recognized by the Undersea and Hyperbaric Medical Society (UHMS), but research is discovering…
- Trial name
- OXY-SPORT (NCT04366427)
- Testing
- L-HBO, HBO, 30% O2
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Padova
Suicide
Self-hangIng Patient and Hyperbaric Oxygen Therapy _ SIPHON Study
During an attempted hanging, patients present severe neurological distress that can lead to major neuropsychiatric sequelae. These sequelae are notably due to significant cerebral edema related to hanging.
- Trial name
- SIPHON (NCT07461272)
- Testing
- OXYGENE MEDICINAL LIQUIDE AIR PRODUCTS MEDICAL
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille